Folate and Human Development

Edward J. Massaro, John M. Rogers (Herausgeber)

Buch | Softcover

359 Seiten

2010 | Softcover reprint of hardcover 1st ed. 2002
Humana Press Inc. (Verlag)
978-1-61737-262-9 (ISBN)

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An authoritative panel of basic and clinical researchers critically reviews the latest findings on the role of folate in human development, health, and disease. Specific areas addressed include folate metabolism in zinc or copper deficiencies, choline and folate in development, animal models of folate-related birth defects, developmental toxicants potentially acting via folate perturbation, and folate's role in vascular disease in women. There are also cutting-edge discussions of genes and neural tube development, folate receptor polymorphism and the risk for neural defects, abnormal DNA synthesis and methylation with folate/methyl insufficiency, and folic acid and homocysteine as risk factors for neural tube defects.

1 • Animal Models of Folate-Related Neural Tube Defects.- 2 • Genetic Variation in Folate Metabolism: Impacton Development.- 3 • Folate Deficiency and the Molecular Determinants of Chromosome Instability: Possible Link to Meiotic Nondisjunction and Down Syndrome.- 4 • Folic Acid, Vitamin B12, and Genomic Stability of Human Cells.- 5 • Molecular Genetics of Folate Metabolism.- 6 • Folate Receptor-?: An Update.- 7 • Folate, Homocysteine, and Neural Tube Defects.- 8 • Folic Acid and Homocysteine as Risk Factors for Neural Tube Defects.- 9 • Developmental Toxicants Potentially Acting via Folate Perturbation.- 10 • Brain Development and Choline, the Other Methyl Donor.- 11 • Nutrient Interactions Between Folate and Zinc or Copper: Their Possible Implications to Pregnancy Outcome.- 12 • Regulation of Folate Metabolism by Iron.- 13 • A Differential Role for Folate in Developmental Disorders, Vascular Disease, and Other Clinical Conditions: The Importance of Folate Status and Genotype.- 14 • Vascular Disease in Women: Folate and Homocysteine.- 15 • Folate, Homocysteine, and Cardiovascular Disease.

Erscheint lt. Verlag	5.11.2010
Zusatzinfo	XII, 359 p.
Verlagsort	Totowa, NJ
Sprache	englisch
Maße	152 x 229 mm
Themenwelt	Medizin / Pharmazie ► Gesundheitsfachberufe ► Diätassistenz / Ernährungsberatung
	Studium ► Querschnittsbereiche ► Prävention / Gesundheitsförderung
	Naturwissenschaften ► Biologie ► Biochemie
	Technik ► Lebensmitteltechnologie
	Weitere Fachgebiete ► Land- / Forstwirtschaft / Fischerei
ISBN-10	1-61737-262-5 / 1617372625
ISBN-13	978-1-61737-262-9 / 9781617372629
Zustand	Neuware