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Enzyme Catalysis in Organic Synthesis

A Comprehensive Handbook
Online Resource
1596 Seiten
2008 | 2nd, Completely Revised and Enlarged Edition
Blackwell Verlag GmbH (Hersteller)
978-3-527-61826-2 (ISBN)
CHF 909,95 inkl. MwSt
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Offers answers to various questions on enzyme catalysis - from searching for suitable catalytic systems via choosing the optimal reaction conditions to implementing modern synthesis strategies. This title provides synthetic chemists with access to first-hand information necessary for successfully using enzymes.
Organic synthesis with enzymes - the only way

This comprehensive set gives reliable answers to all questions on enzyme catalysis - from searching for suitable catalytic systems via choosing the optimal reaction conditions to implementing modern synthesis strategies. The long-awaited new edition has been greatly expanded to include new topics and to reflect the latest research, yet retains the clear and practice-oriented presentation found in the first edition. More than a mere data collection, the three volumes provide synthetic chemists with easy access to all the first-hand information necessary for successfully using enzymes:
- the latest synthesis methods
- example applications arranged according to reaction type
- a table of all the important, commercially available enzymes
- comprehensive registers for targeted searching according to enzyme, compound, or reaction
- current references to the literature
In short, an indispensable reference that should be on the shelf of every modern synthesis laboratory.

Karlheiz Drauz is Vice President of International Scientific Relations of Evonik. He evaluates interesting topics in research and development and networks globally with academic and industrial institutions. He did his Ph.D. at the Technical University Stuttgart, Germany, and started his career at Degussa 1980 in various positions in research and development. His research interests include amino acids, peptides, biological active compounds, asymmetric synthesis, metal and biocatalysis as well as process chemistry. He holds about 160 patents, about 100 scientific publications. Since 1992 he is honorary professor for organic chemistry at the University Wurzburg, Germany. Herbert Waldmann obtained his PhD in organic chemistry from the University of Mainz, Germany, in 1985 working with Professor H. Kunz, after which he completed a postdoctoral appointment with Professor G. Whitesides at Harvard University - USA -. He was appointed as Professor of Organic Chemistry at the University of Bonn - 1991 -, full Professor of Organic Chemistry at the University of Karlsruhe - 1993 -, and Director at the Max-Planck-Institute of Molecular Physiology Dortmund and Professor of Organic Chemistry at the University of Dortmund, Germany, in 1999. He has received numerous awards, e.g. the Otto-Bayer-Award - 2001 -, the Max Bergmann Medal - 2003 -, and recently the Emil-Fischer-Prize - 2012 -. His research interests lie in bioactive compound development, target identification, and the chemical biology of Ras proteins.

Introduction
Production and Isolation of Enzymes
Rational Design of Functional Proteins
Enzyme Engineering by Directed Evolution
Enzyme Bioinformatics
Immobilization of Enzymes
Reaction Engineering for Enzyme-Catalyzed Biotransformations
Enzymic Conversions in Organic and Other Low-Water-Media
Enzymatic Kinetic Resolution
Enzymes from Extreme Thermophilic and Hyperthermophilic Archaea and Bacteria
Hydrolysis and Formation of C-O Bonds
Hydrolysis and Formation of C-N Bonds
Formation and Cleavage of P-O Bonds
Formation of C-C Bonds
Reduction Reactions
Oxidation Reactions
Isomerizations
Introduction and Removal of Protecting Groups
Replacing Chemical Steps by Biotransformations: Industrial Application and Processes Using Biocatalysis
Tabular Survey of Commercially Available Enzymes

Erscheint lt. Verlag 15.4.2008
Verlagsort Berlin
Sprache englisch
Themenwelt Naturwissenschaften Chemie
ISBN-10 3-527-61826-0 / 3527618260
ISBN-13 978-3-527-61826-2 / 9783527618262
Zustand Neuware
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