Handbook of Dynein
Pan Stanford Publishing Pte Ltd (Verlag)
978-981-4303-33-0 (ISBN)
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This book draws together recent data on both cytoplasmic and flagellar dyneins and the proteins they interact with, to give readers a clear picture of what is currently known about the structure and mechanics of these remarkable macro-molecular machines. Each chapter is written by active researchers, with a focus on currently used biophysical, biochemical, and cell biological methods. This is a useful handbook for frontline researchers as well as a textbook for advanced students.
Besides comprehensive cover of structural information gained by electron microscopy, electron cryo-tomography, X-ray crystallography, and nuclear magnetic resonance, this book provides detailed descriptions of mechanistic experiments by single-molecule nanometry. The reports include in vitro studies of the motility of reconstituted complexes and in vivo studies of organisms expressing mutant dyneins. The recent technical improvements described, which have played an important part in recent advances, include the expression and preparation of recombinant dynein heavy chains or individual subdomains.
Keiko Hirose is Senior Research Scientist at the National Institute of Advanced Industrial Science and Technology in Japan. Linda A. Amos is Group Leader at the MRC Laboratory of Molecular Biology in Cambridge, UK.
Dyneins: Ancient Protein Complexes Gradually Reveal Their Secrets,. Two Decades of Cytoplasmic Dynein: From Fast to Forceful. Functional Analysis of the Dynein Motor Domain. Structural Studies on the Dynein Heavy Chain. Structural Analysis of Microtubule-Bound Dynein. The Dynein Stalk: Atomic Structure and Roles in the Mechanism of the Dynein Motor. Enzymatic and Motile Properties of Native Dynein Molecules. Motile Properties of Cytoplasmic Dynein. Motile Properties of Inner Arm Dynein. Dynein Motility in Cilia and Flagella. 3D Structures of Axonemes, T. IshikawaFunctional Diversity of Axonemal Dyneins. Assembly and Regulation of Dynein Light Chains. Regulatory Subunits of Axonemal Dynein. The Role of Dynein in Yeast Nuclear Segregation.
| Zusatzinfo | 34 Illustrations, color; 48 Illustrations, black and white |
|---|---|
| Verlagsort | Singapore |
| Sprache | englisch |
| Maße | 152 x 229 mm |
| Gewicht | 680 g |
| Themenwelt | Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie |
| Naturwissenschaften ► Biologie ► Zellbiologie | |
| Technik ► Umwelttechnik / Biotechnologie | |
| ISBN-10 | 981-4303-33-X / 981430333X |
| ISBN-13 | 978-981-4303-33-0 / 9789814303330 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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