Insulin Receptor Substrate Signaling in the Central Nervous System
Seiten
2011
Nova Science Publishers Inc (Verlag)
978-1-61668-255-2 (ISBN)
Nova Science Publishers Inc (Verlag)
978-1-61668-255-2 (ISBN)
The advances in molecular biology revealed insights into the function of insulin receptor signalling and insulin receptor substrate (IRS) protein mediated signals in the central nervous system (CNS) in vivo. This book examines why IRS signalling is critical during brain development, and for reproduction, energy homeostasis, and ageing.
Recent advance in molecular biology revealed new insights into the function of insulin receptor signalling and insulin receptor substrate (IRS) protein mediated signals in the central nervous system (CNS) in vivo. The IRS proteins mediate mainly intracellular effects of the insulin-like growth factor-1 receptor (IGF-1R) and the insulin receptor (IR). The functions of IRS proteins in peripheral tissues like muscle, liver, pancreas and fat have been characterised in detail. This book examines why IRS signalling is not only critical during brain development, but also for reproduction, energy homeostasis, ageing and possibly for neurodegenerative diseases in humans.
Recent advance in molecular biology revealed new insights into the function of insulin receptor signalling and insulin receptor substrate (IRS) protein mediated signals in the central nervous system (CNS) in vivo. The IRS proteins mediate mainly intracellular effects of the insulin-like growth factor-1 receptor (IGF-1R) and the insulin receptor (IR). The functions of IRS proteins in peripheral tissues like muscle, liver, pancreas and fat have been characterised in detail. This book examines why IRS signalling is not only critical during brain development, but also for reproduction, energy homeostasis, ageing and possibly for neurodegenerative diseases in humans.
Introduction; IRS & IRS-like protein signal transduction; IRS & IRS-like protein receptors; Peripheral functions of IRS & IRS-like proteins; IRS signaling system in the CNS; IRS signaling in pre-and postnatal brain development; IRS signaling in CNS disease; IRS signaling in metabolism & energy homeostasis; IRS signaling & fertility; IRS signaling in aging; Conclusion; Index.
| Zusatzinfo | Illustrations |
|---|---|
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 230 x 155 mm |
| Gewicht | 136 g |
| Themenwelt | Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| ISBN-10 | 1-61668-255-8 / 1616682558 |
| ISBN-13 | 978-1-61668-255-2 / 9781616682552 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
| Haben Sie eine Frage zum Produkt? |
Mehr entdecken
aus dem Bereich
aus dem Bereich
