Transporters as Drug Targets
Seiten
Wiley-VCH (Verlag)
978-3-527-31725-7 (ISBN)
- Titel wird leider nicht erscheinen
- Artikel merken
The modern view on the molecular biology and pharmacology of a prime target class for blockbuster drugs against depression and anxiety. A comprehensive resource for medicinal chemists, neurophysiologists and pharmacologists alike.
A modern approach to the molecular biology and pharmacology of this prime target class for blockbuster drugs against depression and anxiety. Following an introduction, this handbook goes on to discuss such families as biogenic amine transporters, excitatory, inhibitory and heterodimeric amino acid transporters, before looking at the 3D structure of transporter targets. The final section on ligand-based approaches includes pharmacophore models as well as SAR and QSAR studies.A comprehensive resource for medicinal chemists, neurophysiologists and pharmacologists alike.
A modern approach to the molecular biology and pharmacology of this prime target class for blockbuster drugs against depression and anxiety. Following an introduction, this handbook goes on to discuss such families as biogenic amine transporters, excitatory, inhibitory and heterodimeric amino acid transporters, before looking at the 3D structure of transporter targets. The final section on ligand-based approaches includes pharmacophore models as well as SAR and QSAR studies.A comprehensive resource for medicinal chemists, neurophysiologists and pharmacologists alike.
Hugo Kubinyi gehört seit 1985 der BASF AG an, wo Kombinatorische Chemie, Molecular Modelling und Wirkstoffdesign zu seinen Tätigkeitsfeldern zählten. Sein Spezialgebiet sind Struktur-Wirkungs-Beziehungen und QSAR-Methoden.
Introduction
TRANSPORTER FAMILIES
Biogenic Amine Transporters
Excitatory Amino Acid Transporters
Inhibitory Amino Acid Transporters
Heterodimeric Amino Acid Transporters
3D STRUCTURE OF TRANSPORTER TARGETS
Crystal StructuresHomology Modeling
LIGAND-BASED APPROACHES
Pharmacophore Models
SAR and QSAR Studies
| Reihe/Serie | Methods and Principles in Medicinal Chemistry |
|---|---|
| Zusatzinfo | w. 15 col. ill. |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Pharmazie |
| Naturwissenschaften ► Chemie | |
| Schlagworte | Arzneimittel • Biochemie • Medizinische Chemie • Pharmazeutische Chemie |
| ISBN-10 | 3-527-31725-2 / 3527317252 |
| ISBN-13 | 978-3-527-31725-7 / 9783527317257 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
| Haben Sie eine Frage zum Produkt? |
Mehr entdecken
aus dem Bereich
aus dem Bereich
mikroskopisches Praktikum
Buch | Softcover (2025)
Deutscher Apotheker Verlag
CHF 39,20
Pharmaceuticals, Diagnostics, Medical Devices
Buch | Hardcover (2023)
Wiley-VCH (Verlag)
CHF 138,60
