Research Protocols for Ophthalmic Disease Mechanisms and Therapeutics: Glaucoma - Ocular Hypertension (eBook)
516 Seiten
Bentham Science Publishers (Verlag)
9789815324334 (ISBN)
Research Protocols for Ophthalmic Disease Mechanisms and Therapeutics: Glaucoma - Ocular Hypertension offers a detailed, step-by-step protocols for isolating, characterizing, and analyzing cells and tissues of the eye's anterior segment-where OHT originates-using techniques from molecular biology, pharmacology, and histology.
Across eight thematic sections, the book covers ocular anatomy, drug screening, receptor localization, cell-based assays, in vitro and in vivo models, drug formulation, and cutting-edge technologies such as gene editing, single-cell RNA sequencing, and stem cell therapies. Each protocol is designed to support reproducibility and translational relevance.
Key Features:
-Details validated protocols for drug discovery and disease modeling
-Demonstrates methods for studying receptor function and pharmacokinetics
-Provides animal models and ex vivo systems to evaluate therapeutic strategies
-Incorporates emerging tools such as CRISPR, metabolomics, and exosomes
-Bridges experimental design with clinical relevance for glaucoma research
List of Contributors
| Anthonia Okolie | Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, Texas, USA |
| Amy Chen | Department of Ophthalmology, Novartis Institute of Biomedical Research, 22 Windsor St. Cambridge, MA-02452, USA |
| Andrea M. Unser | Colleges of Nanoscale Science and Engineering, SUNY Polytechnic Institute, 257 Fuller Road, Albany 12203, New York, USA |
| Aparna Rao | Hyderabad Eye Research Foundation, , , , LV Prasad Eye Institute, Patia, Bhubaneswar, MTC Campus, Bhubaneswar, Odisha, India |
| Alyssa Hostert | Department of Pharmacy Sciences, School of Pharmacy and Health Professions, Creighton University, Omaha, Nebraska, USA |
| Anna Van Koeverden | Department of Optometry & Vision, 202 Berkeley St, Parkville, The University of Melbourne, Victoria 3010, Australia |
| Abdelrahman Anter | Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA |
| Adnan Dibas | Nanoscope Technologies, 1312 Brown Trail, Bedford, TX 76022, USA |
| Alex Leung | UCL Institute of Ophthalmology, University College London, London, United Kingdom |
| Anna Mueller | Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA |
| Brianna Caroline Afiat | Department of Optometry & Vision, 202 Berkeley St, Parkville, The University of Melbourne, Victoria 3010, Australia |
| Bang Viet Bui | Department of Optometry & Vision, 202 Berkeley St, Parkville, The University of Melbourne, Victoria 3010, Australia |
| Betsy Benitez | Miami Integrative Metabolomics Research Center, Miami, FL 33136, USA |
| Catherine A. Opere | Department of Pharmacy Sciences, School of Pharmacy and Health Professions, Creighton University, Omaha, Nebraska, USA |
| Christopher W. Wilson | Department of Ophthalmology, Novartis Institute of Biomedical Research, 22 Windsor St. Cambridge, MA-02452, USA |
| Christine Tram Oanh Nguyen | Department of Optometry & Vision, 202 Berkeley St, Parkville, The University of Melbourne, Victoria 3010, Australia |
| Carol B. Toris | Havener Eye Institute, Department of Ophthalmology and Visual Sciences, The Ohio State University Wexner Medical Center, 915 Olentangy River Rd, Suite 3010B, Columbus, OH 43212, USA |
| Charles E. Amankwa | Department of Pharmacology and Neuroscience and The North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, TX 76107, USA |
| Dorette Z. Ellis | Department of Pharmaceutical Sciences, University of North Texas System College of Pharmacy, North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, Texas, USA |
| Da Zhao | Department of Optometry & Vision, 202 Berkeley St, Parkville, The University of Melbourne, Victoria 3010, Australia |
| Dharmalingam Kuppamuthu | Department of Biotechnology, Aravind Medical Research Foundation - Affiliated to Alagappa University, Karaikudi, Tamil Nadu, India Department of Proteomics, Aravind Medical Research Foundation, Madurai, Tamil Nadu, India |
| Fatima Muili | Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, Texas, USA |
| Fatima Shirazee | Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada |
| Ganesh Prasanna | Department of Ophthalmology, Novartis Institute of Biomedical Research, 22 Windsor St. Cambridge, MA-02452, USA |
| Gowri Priya Chidambaranathan | Department of Immunology and Stem Cell Biology, Aravind Medical Research Foundation, Madurai, Tamil Nadu, India Department of Biotechnology, Aravind Medical Research Foundation - Affiliated to Alagappa University, Karaikudi, Tamil Nadu, India |
| Gulab Zode | Department of Pharmacology and Neuroscience and The North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, TX 76107, USA |
| Hanna Rao | Department of Arts and Science, McMaster University, Hamilton, Ontario, Canada |
| Iswarya Radhakrishnan | Department of Immunology and Stem Cell Biology, Aravind Medical Research Foundation, Madurai, Tamil Nadu, India Department of Biotechnology, Aravind Medical Research Foundation - Affiliated to Alagappa University, Karaikudi, Tamil Nadu, India |
| Isabella Moceri | Miami Integrative Metabolomics Research Center, Miami, FL, 33136, USA |
| J. Cameron Millar | North Texas Eye Research Institute (NTERI), Department of Pharmacology & Neuroscience, University of North Texas Health Science Center (UNTHSC), 3500 Camp Bowie Boulevard, Room IREB-511, Fort Worth, TX 76107, USA |
| Judith West-Mays | Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada |
| James E. Chastain | Novartis Institutes for BioMedical Research (Retired), The Woodlands, 26 Dawning Flower Dr., The Woodlands, TX 77375, USA |
| Jack Hopkins | UCL Institute of Ophthalmology, University College London, London, United Kingdom |
| Karen Y. Torrejon | Colleges of Nanoscale Science and Engineering, SUNY Polytechnic Institute, 257 Fuller Road, Albany 12203, New York, USA |
| Kalu K. Ngele | Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, Texas, USA |
| Krishnadas Subbaiah | Glaucoma Services, Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, Madurai, Tamil Nadu, India |
| Len Pinchuk | Research & Development, InnFocus Inc. (A Santen Co.), 12415 S.W. 136 Ave., Unit 3, Miami, FL 33186, USA |
| Mary J. Kelley | Department of Ophthalmology, Casey Eye Institute Oregon Health & Science University Portland, Oregon, USA |
| Mohammad Shahidullah | Department of Physiology and Department of Ophthalmology & Vision Science, College of Medicine, University of Arizona, 1501 N Campbell Avenue, Tucson, AZ 85724, USA |
| Munmun Chakraborthy | Hyderabad Eye Research Foundation, , , , LV Prasad Eye Institute, Patia, Bhubaneswar, MTC Campus, Bhubaneswar, Odisha, India |
| Muthukkaruppan Veerappan | Department of Immunology and Stem Cell Biology, Aravind Medical Research Foundation, Madurai, Tamil Nadu, India |
| Erscheint lt. Verlag | 8.8.2025 |
|---|---|
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Augenheilkunde |
| ISBN-13 | 9789815324334 / 9789815324334 |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
| Haben Sie eine Frage zum Produkt? |
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