Molecular Biology of Cancer
Oxford University Press (Verlag)
978-0-19-889969-3 (ISBN)
- Noch nicht erschienen (ca. März 2026)
- Versandkostenfrei
- Auch auf Rechnung
- Artikel merken
Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students.
Key features
- Describes the theoretical basis of cancer biology and shows how this theory is applied to develop new cancer therapies, giving students a clear appreciation of how theoretical knowledge can be translated into therapeutic strategies
- Draws on the latest research in cancer biology
- Features a variety of learning features to help students engage with the concepts presented: 'Pause and think'; 'How do we know that?'; 'In the clinic'; self-tests; and activities
New to this edition
- New themes that weave throughout the book, such as the two-way interactions between the microenvironment and the tumour, systemic effects of cancer, and the role of plasticity and heterogeneity in cancer evolution
- Expanded coverage of cancer genomics, including single cell genomics and spatial transcriptomics, highlighted in the concluding chapter
- A new feature called 'In the clinic' that highlights current or potential applications of cancer biology to clinical practice
- Updates on newly approved cancer therapeutics
- Includes additional primary data from the literature and key references to provide a resource of up-to-date experimental evidence
- Expanded artwork programme and new 'figure sequences' (in the enhanced e-book) to help readers understand molecular pathways over time
Digital formats and resources
The 6th edition is available for students and institutions to purchase in a variety of formats: the e-book and Science Trove offer a mobile experience and convenient access along with multiple choice questions, audio clips, functionality tools, navigation features and links that offer extra learning support.
For more information about e-books, please visit https://www.oxfordtextbooks.co.uk/ebooks
Professor Lauren Pecorino obtained her PhD in Cell and Developmental Biology at the State University of New York at Stony Brook, USA. She then moved to London to carry out a post-doctoral tenure at the Ludwig Institute for Cancer Research where she studied the phenomenon of limb regeneration. Here she used a technique called biolistics, using a 'gene gun' to shoot gold bullets coated with DNA to introduce genes into the regenerating limbs of live newts. Since 1996, Lauren has been a member of academic staff at the University of Greenwich, where she developed her interest in teaching Cancer Biology. She is a Fellow of the Royal Society of Medicine, Fellow of the Royal Society of Biology, and Senior Fellow of the Higher Education Academy.
1: Introduction
2: The transformable cancer genome: mutations versus repair
3: Regulation of gene expression
4: Growth factor signaling and oncogenes
5: The cell cycle
6: Tumour suppressor genes
7: Apoptosis
8: Cancer stem cells, lineage plasticity and disrupted differentiation: focus on colon cancer and leukemias
9: Metastasis
10: Angiogenesis
11: Reprogrammed metabolism and diet
12: Tumour immunology and immunotherapy
13: Inflammation, infection, and the microbiome
14: Cancer genomics and other methods for research and clinical development
| Erscheint lt. Verlag | 1.3.2026 |
|---|---|
| Verlagsort | Oxford |
| Sprache | englisch |
| Maße | 189 x 246 mm |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| ISBN-10 | 0-19-889969-6 / 0198899696 |
| ISBN-13 | 978-0-19-889969-3 / 9780198899693 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
| Haben Sie eine Frage zum Produkt? |
aus dem Bereich
