Molecular Diagnostics
Humana Press (Hersteller)
978-1-59259-928-8 (ISBN)
An Historical Perspective on the Clinical Diagnostic Laboratory.- Basic Molecular Biology.- An Overview of Nucleic Acid Chemistry, Structure, and Function.- Extraction of Nucleic Acids.- Nucleic Acid Blotting Techniques.- The Polymerase Chain Reaction.- Bioinformatics.- Molecular Diagnostic Technologies.- PCR-Based Methods for Mutation Detection.- Alternative Methods for Amplified Nucleic Acid Testing.- Electrophoretic Methods for Mutation Detection and DNA Sequencing.- Single-Nucleotide Polymorphisms.- Microarray Approaches to Gene Expression Analysis.- Methods for Analysis of DNA Methylation.- Other Clinical Diagnostic Technologies.- Flow Cytometry.- Medical Cytogenetics.- Fluorescence In Situ Hybridization.- Immunohistochemistry.- Laser Capture Microdissection.- Quality Assurance in the Molecular Diagnostics Laboratory.- Framework for Quality Assurance in Molecular Diagnostics.- Verification of Molecular Assays.- Standards and Standardization of Molecular Diagnostics.- Laboratory-Developed Tests in Molecular Diagnostics.- Applications of Molecular Diagnostics for Genetic Diseases.- An Overview of Molecular Genetics.- Genetic Basis of Neurologic and Neuromuscular Diseases.- Molecular Mechanisms of Endocrine Disorders.- Molecular Pathogenesis of Cardiovascular Disease.- Molecular Diagnostics in Coagulation.- Cystic Fibrosis.- Prenatal Genotyping for Identification of Fetuses at Risk for Immune Cytopenic Disorders.- Personalized Medicine.- Applications of Molecular Diagnostics for Human Cancers.- Molecular Pathogenesis of Human Cancer.- Application of Molecular Diagnostics to Hereditary Nonpolyposis Colorectal Cancer.- Molecular Genetic Applications to the Diagnosis of Lymphoma.- Molecular Genetic Abnormalities in Acute and Chronic Leukemias.- Applications of MolecularDiagnostics for Infectious Diseases.- Molecular Testing for Chlamydia trachomatis and Neisseria gonorrhoeae.- Human Papillomavirus.- Molecular Diagnostics for HIV-1.- Hepatitis C.- Cytomegalovirus.- Applications of Molecular Diagnostics for Identity-Based Testing.- HLA Typing Using Molecular Methods.- Molecular Analysis for Forensic Casework and Parentage Testing.- Molecular Assessment of Bone Marrow Transplant Engraftment.- Use of DNA-Based Identity Testing for Specimen Identification.- Issues for the Clinical Molecular Pathology Laboratory.- Genetic Counseling Considerations in Molecular Diagnosis.- Ethical, Social, and Legal Issues Related to Molecular Genetic Testing.
| Erscheint lt. Verlag | 28.10.2007 |
|---|---|
| Zusatzinfo | XVIII, 567 p. |
| Verlagsort | Totowa |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete |
| Studium ► 2. Studienabschnitt (Klinik) ► Pathologie | |
| Schlagworte | Bioinformatics • Diagnostics • DNA • DNA sequencing • gene expression • genes • Genetics • Hybridization • Infectious Diseases • Laboratory • PCR • Polymer • Virus |
| ISBN-10 | 1-59259-928-1 / 1592599281 |
| ISBN-13 | 978-1-59259-928-8 / 9781592599288 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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