Inflammation in the Brain and the Body

A Mind-Body Hypothesis

John D. Matthews (Autor)

Buch | Softcover

264 Seiten

2026
American Psychiatric Association Publishing (Verlag)
978-1-61537-426-7 (ISBN)

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Despite the wealth of evidence showing that psychological conditions can affect physical health—for example, the impact of stress on blood pressure—it is not uncommon, even now, for disorders of the mind and body to be viewed and treated independently of one another. But what if the same inflammatory processes that are responsible for heart failure, diabetes, renal failure, allergies, and many other medical conditions were the root cause of most major psychiatric disorders?

This is the premise of this paradigm-shifting new book, which proposes approaching mental illnesses as disorders of the whole body, not just the brain. It reviews the extensive emerging evidence that inflammation contributes to the pathophysiology of not only medical disorders but also mood, anxiety, psychotic, cognitive, and trauma-related conditions.

Using major depressive disorder as the case example, this volume integrates information from different fields as it examines:

• How multiple sources of inflammation—including the gut microbiome, early and chronic stress, lifestyle, and social determinants of health—affect the body and the brain
• Strategies for incorporating a whole-body disorder model into psychiatric, medical, and lifestyle patient assessments
• Interventions such as cognitive-behavioral therapy, lifestyle changes, stress management, and quality nutrition

By pursuing new research avenues to illustrate the bidirectional nature between medical and mental disorders, Inflammation in the Brain and the Body: A Mind-Body Hypothesis expands the universe of treatment options for both types of disorders, providing multiple augmentation treatment strategies.

John D. Matthews, M.D., M.Sc. is a Senior Psychiatrist at the Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, and Assistant Professor of Psychiatry at Harvard Medical School in Boston, Massachusetts.

Chapter 1: Introduction
Part 1: The Science Behind the Model
Chapter 2: Inflammation in the Brain and the Body
Chapter 3: Sources of Inflammation
Chapter 4: Inflammation and Epigenetics
Chapter 5: A Model of Inflammation and Mind-Body Disorders
Part 2: Assessment
Chapter 6: Assessment of Inflammation
Part 3: Interventions
Chapter 7: Medication Interventions
Chapter 8: Psychotherapy Interventions
Chapter 9: Stress Management Interventions
Chapter 10: Diet Interventions
Chapter 11: Exercise Interventions
Chapter 12: Sleep Interventions
Chapter 13: Addictions Interventions
Chapter 14: Conclusion

Erscheinungsdatum	30.12.2025
Zusatzinfo	16 Line drawings, black and white; 2 Tables, unspecified
Verlagsort	VA
Sprache	englisch
Maße	152 x 229 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Psychiatrie / Psychotherapie
ISBN-10	1-61537-426-4 / 1615374264
ISBN-13	978-1-61537-426-7 / 9781615374267
Zustand	Neuware