Bioimaging in Tissue Engineering and Regeneration
Springer International Publishing (Verlag)
9783031915437 (ISBN)
This reference work gives a comprehensive overview about how to fully exploit the potential of bioimaging to characterize tissue regeneration holistically and to gain complementary, multi-scale information about relevant structure, function, dynamics and molecular composition. To keep pace with the highly dynamic nature of the field and fast-developing imaging technology, it is essential to allow its Live Reference version to be updated and dynamic. It guides the reader through real-case biomedical applications organized by chapter and gives a tissue-specific overview on how to best assess parameters of interest. Additionally, all imaging techniques, including emerging modalities, are explained in great detail and enables the reader to understand the physical principles behind each imaging modality. The book provides a unique overview of available biological and (pre)clinical imaging techniques in the field and enables the reader to understand their benefits and limitations for real-case applications. The reader will be equipped with a comprehensive tool to properly chose the most promising technique for her/his biomedical research question - and respond to novel trends due to the dynamic nature of the Live Reference version available online. The book is of high interest to all researchers, physicians, physicists and life scientists working in the field to deepen their theoretical and practical knowledge about bioimaging and about the wide range of tissue-specific biomedical applications. The book is a valuable reference in the field for bioimaging.
Andreas Walter studied physics and biophysics at the University of Heidelberg and in Sankt Petersburg on a Baden-Wuerttemberg Scholarship. He spent his research career developing and applying various imaging techniques for life sciences, including advanced fluorescence, super-resolution, cryo-light, transmission electron, scanning electron and soft X-ray microscopy. After his tenure as a guest scientist at the European Molecular Biology Laboratory, he did his PhD at the Max Planck Institute of Biophysics on method development in cryo-electron microscopy. He finished his studies with distinction. He continued his research in imaging and worked as a postdoc and DFG fellow at the University of California San Francisco and at the Lawrence Berkeley National Laboratory to correlate soft x-ray tomography and cryo-light microscopy. He is also a fellow of the German Scholars Organization. Dr. Walter was appointed Director of Austrian BioImaging/CMI in October 2016 (www.bioimaging-austria.at). He is also Chair of the EU-funded COST Action COMULIS (CA17121).
Paul Slezak, MD, graduated in 2009 at the Medical University of Vienna, Austria. He leads a research group on soft tissue regeneration and local hemostasis at the Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, developing next generation therapies and hemostats. He is member of the steering board of the Correlated Multimodal Imaging Node Austria (CMI) and member of the TERMIS EU industry committee. Next to his research interests Dr. Slezak is the CEO of a Spin Off company which aims to bring experimental therapies and approaches to the clinical field.
Ralph Müller is a Professor of Biomechanics at ETH Zurich. He received his doctoral degree in Electrical Engineering from ETH Zurich in 1994. The research he is currently pursuing employs state-of-the-art biomechanical testing and simulation techniques as well as novel bioimaging and visualization strategies for musculoskeletal tissues. His approaches are now often used for precise phenotypic characterization in mammalian genetics, mechanobiology as well as tissue engineering and regenerative medicine. He is a prolific author of over 500 peer-reviewed publications in international scientific journals and conference proceedings. His work has been cited over 40,000 times with an h-index of 100.
Greet Kerckhofs obtained her PhD in Engineering in 2009 (KU Leuven). Since 2017, she is Professor at the UCLouvain and Visiting Professor at the KU Leuven. Her research group (ContrasTTeam) focusses on the optimization and application of contrast-enhanced microfocus computed tomography (CECT) imaging of biological tissues, hereby setting the stage for a new era of virtual 3D histology. Furthermore, the group is pioneering in 4D-CECT, combining CECT imaging with in-situ loading. Prof. Kerckhofs is (co-)author of 57 peer-reviewed publications, more than 140 conference contributions and 2 book chapters. She has an h-index of 27 and more than 3500 citations.
Baubak Bajoghli obtained his PhD in Biology and Genetics from the University of Vienna in 2007. He subsequently conducted postdoctoral research in cell and developmental biology, evolution, and immunology at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg, followed by an EMBL-Marie Curie Interdisciplinary Postdoctoral Fellowship (EIPOD) at the European Molecular Biology Laboratory (EMBL) in Heidelberg. As a tenured Principal Investigator, he led a research group at the University Hospital in Tübingen, focusing on translational research. He and his team implemented multidisciplinary approaches, including advanced imaging, mathematics, and computational modeling, to investigate T-cell development - both normal and malignant - in the thymus. Since 2022, he has been Director of Austrian BioImaging/CMI.
Fluorescence Microscopy of the Cell and Cell Interactions to Study Dynamic Cellular Processes.- Live Cell Imaging and in vivo Cell Tracking in Tissues.- Nonlinear Microscopy to Study Arthroscopy.- Synchronization to Visualization: Dissecting Myogenesis and Regeneration Using Correlative Light and Electron Microscopy (CLEM).- Raman Imaging for Biomedical Applications.- X-Ray-Based 3D Histo(patho)logy of Biological Tissues Using Contrast-Enhanced MicroCT.- Live Cell Imaging by High Resolution Quasi-Spectral Microscopy.- Confocal Microscopy Applications with Integrative Techniques in Cell Mechanics and Tissue Engineering.- Correlated Multimodal Imaging in Bone of Regeneration - A Showcase of Bisphosphonate-Treated Murine Jawbones.- Chemical Imaging in Bone and Cartilage Regeneration.- Quantitative Microstructural Imaging and Mechanics of Cartilage Using Experimental and Computational Approaches.- Osteoarthritis Imaging Using MRI.- Correlative Multimodal Imaging for Multiscale Analysis of Complex Biological Systems: Validation Methods and Performance Analysis.- HREM for Mesoscopic 3D Histology.- X-Ray Physics and Micromechanics-Guided Intravoxel Analysis of microCT-Imaged Hard Tissue Engineering Scaffolds and Bone.- Combined Imaging and Soft and Complex 3D Bioprinting Using Light Sheet Fluorescence Microscopy.
| Erscheinungsdatum | 26.08.2025 |
|---|---|
| Reihe/Serie | Reference Series in Biomedical Engineering | Tissue Engineering and Regeneration |
| Zusatzinfo | XXI, 500 p. |
| Verlagsort | Cham |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Themenwelt | Medizin / Pharmazie ► Physiotherapie / Ergotherapie ► Orthopädie |
| Technik | |
| Schlagworte | Biobanking • Biomaterial degradation • chemical imaging • electron microscopy • Fluorescence Microscopy • force spectroscopy • Functional Imaging • Image data integration • Imaging angiogenesis • Imaging in tissue regeneration • In vivo cell tracking • Mass spec imaging • MRI nanoparticles • Multimodal correlative imaging • Nerve tissue imaging • PET/CT • PET/MRI • Soft tissue imaging • Tissue-material interaction |
| ISBN-13 | 9783031915437 / 9783031915437 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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