Animal Models of Neurological Conditions

A Reference Guide for Neuroscience Researchers and Trainees

Buch | Hardcover

502 Seiten

2025
Academic Press Inc (Verlag)
978-0-443-29090-9 (ISBN)

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Animal Models of Neurological Conditions informs about novel animal models and their unique strengths and limitations in the research of neurological conditions. It demonstrates the importance of animal models’ abilities to replicate only aspects of a given neurological condition and highlights the value of these animal models in increasing human brain function in afflicted patients. This book, comprised of thirteen chapters discusses various animal models and research methods for mental health, neurodevelopmental disorders, addiction, age-related neurodegenerative conditions, and viruses affecting brain function. Although developed with neuroscience researchers and trainees involved in pre-clinical and clinical research in mind, neurologists and other treatment professionals caring for patients with neurological conditions will also find value in this detailed resource.

This is an invaluable resource for neuroscience researchers, trainees, and healthcare professionals.

Jacob Raber, PhD received his BS in Chemistry and MS in Pharmacochemistry from the Free University of Amsterdam, his PhD in Molecular Genetics and Virology from the Weizmann Institute of Science, and further training under Floyd Bloom at the Scripps Research Institute, La Jolla, and Lennart Mucke at the Gladstone Institutes and UCSF. In 2001 he was recruited to Oregon Health & Science University (OHSU) in Portland, Oregon and currently serves as a professor in the Departments of Behavioral Neuroscience, Neurology, Psychiatry, and Radiation Medicine, an affiliate scientist in the division of Neuroscience at the ONPRC, and a Courtesy Professor in the College of Pharmacy at Oregon State University. He was an Ellison Medical Foundation New Scholar in Aging from 2002-2006. Dr Raber’s research is devoted to characterizing effects of environmental and genetic factors on brain function, identifying of affected pathways, and developing treatments to antagonize detrimental effects.

Section 1: Animal models of alcohol and drugs of abuse
1. Mouse behavioral models of alcohol and drug hedonic effects
2. Nonhuman primate models of fetal alcohol spectrum disorders

Section 2: Posttraumatic stress disorder animal models
3. Rodent models of posttraumatic stress disorder

Section 3: Animal models of traumatic brain injury
4. Mouse models of traumatic brain injury

Section 4: Animal models of ischemic and vascular conditions
5. Sheep model of hypoxia to the developing brain
6. Animal models of ischemic and hemorrhagic stroke
7. Animal models of depression: a novel preclinical framework for post-myocardial infarction depression

Section 5: Animal models of mild cognitive impairment
8. Nonhuman primate model of mild cognitive impairment

Section 6: Parkinson’s disease animal models
9. MPTP progressive model of Parkinson’s disease: changes in basal ganglia circuitry and restorative treatment strategies

Section 7: Alzheimer’s disease mouse models
10. Mouse models of Alzheimer’s disease pathology
11. Mouse models of apolipoprotein E

Section 8: Western Pacific ALS/PDC mouse models
12. Animals models of Western Pacific amyotrophic lateral sclerosis and Parkinsonism-dementia complex

Section 9: Second-hand cigarette smoke rodent models
13. Animal models of second-hand cigarette smoke (SHS) exposure in neurodevelopmental disorders and neurodegenerative disease

Section 10: Multiple sclerosis animal models
14. Nonhuman primate models of multiple sclerosis: advantages over rodent models for preclinical studies

Section 11: Hepatitis mouse models
15. Animal models of hepatitis

Erscheinungsdatum	22.11.2025
Verlagsort	San Diego
Sprache	englisch
Maße	152 x 229 mm
Gewicht	450 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
	Naturwissenschaften ► Biologie ► Humanbiologie
	Naturwissenschaften ► Biologie ► Zoologie
ISBN-10	0-443-29090-3 / 0443290903
ISBN-13	978-0-443-29090-9 / 9780443290909
Zustand	Neuware