Azetidine Synthesis

Navjeet Kaur (Autor)

Buch | Softcover

414 Seiten

2025
Elsevier - Health Sciences Division (Verlag)
978-0-443-40350-7 (ISBN)

Infos

Azetidine Synthesis offers a comprehensive exploration of various methods for the synthesis of azetidines, a class of heterocyclic compounds with diverse applications. The significance of azetidine synthesis has grown largely due to the importance of these molecules as constituents of antibiotics. Chapters cover different synthetic pathways, starting with the general synthesis of azetidines and progressing to specific methods using various starting materials. From the copper-catalyzed synthesis of azetidines from nitrones to the synthesis from isoxazoles, oxazines, and diazo compounds, each chapter delves into the unique strategies and mechanisms involved.

Rhodium-catalyzed approaches, cycloaddition reactions of imines to carbonyl compounds, and the use of isocyanides and isocyanates for azetidine synthesis are discussed in detail. The book also explores photochemical methods for azetidine synthesis, including the photochemical synthesis of fused azetidines. By providing a comprehensive overview of diverse synthetic routes to azetidines, this book serves as a valuable resource for researchers and practitioners in the field of organic chemistry, offering insights into the versatility and potential applications of these important heterocyclic compounds.

Autor

Dr. Navjeet Kaur received her BSc from Panjab University Chandigarh (Panjab, India) in 2008. In 2010, she completed her MSc in Chemistry from Banasthali Vidyapith. She was awarded with PhD in 2014 by the same university. With 11 years of teaching experience, she has published over 160 scientific research papers, review articles, book chapters, and monographs in the field of organic synthesis in national and international reputed journals. She has published five authored books: with Elsevier. She secured her place amongst top 2% scientists of the world in 2017 (single year ranking), 2018 (full career wise ranking), 2019 [full career wise ranking with 424 world rank (04 in India) and single year ranking with 03 world rank (01 in India)] and 2020 (full career wise ranking with 372 world rank and single year ranking with 126 world rank). In 2021, Dr. Kaur was chosen as a candidate for membership by Royal Society of Research, London, England, UK with full waiver of application fees. She is serving as an Editor-in-Chief of the “Advanced Chemicobiology Research” journal.

Inhalt

1. Synthesis of azetidines
2. Synthesis of azetidines from azides and cyanides
3. Synthesis of azetidines from aziridines and epoxides
4. Copper-catalyzed synthesis of azetidines from nitrones
5. Synthesis of azetidines from isoxazoles and oxazoles
6. Synthesis of azetidines from oxazines and isoxazoloxazines
7. Synthesis of azetidines from diazo compounds
8. Rhodium-catalyzed synthesis of azetidines from diazo compounds
9. Synthesis of azetidines by cycloaddition of imines to carbonyl compounds using triethylamine
10. Synthesis of azetidines by cycloaddition of imines to carbonyl compounds using lithium reagents
11. Synthesis of azetidines from isocyanides
12. Synthesis of azetidines from isocyanates
13. Photochemical synthesis of azetidines
14. Photochemical synthesis of fused azetidines

Produkt-Details

• Erscheinungsdatum: 01.07.2025
• Verlagsort: Philadelphia
• Sprache: englisch
• Maße: 191 x 235 mm
• Gewicht: 450 g
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• Themenwelt: Naturwissenschaften ► Chemie ► Organische Chemie
• ISBN-10: 0-443-40350-3 / 0443403503
• ISBN-13: 978-0-443-40350-7 / 9780443403507
• Zustand: Neuware