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Nanobioceramics for Bone Tissue Engineering and Regenerative Biomedicine - Reza Gholami, Seyed Morteza Naghib

Nanobioceramics for Bone Tissue Engineering and Regenerative Biomedicine (eBook)

Tunable Biological Characteristics
eBook Download: PDF
2025
X, 282 Seiten
Springer Nature Singapore (Verlag)
978-981-96-0041-0 (ISBN)
Systemvoraussetzungen
149,79 inkl. MwSt
(CHF 146,30)
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This book presents the tunable biological characteristics of nanobioceramics and focuses on some challenges in bone tissue engineering and regenerative medicine. Synthetic composite-based materials and scaffolds should be biodegradable, biocompatible and supply sufficient structural aid for cell migration, along with oxygen, waste, and nutrient carriage to accelerate bone regeneration process and remodeling in defects. These properties may be reached by functioning tunable physical features, including absorption rate, degradation rate, modulus, porosity, and swelling by adjustments with the addition of ceramic phases and copolymers as synthetic composite scaffolds. Synthetic bioceramics seek to imitate the natural hydroxyapatite (HA) crystal creation located in bone. These ceramics, particularly calcium phosphates, have exhibited great osteoinductivity, osteoconductivity, and biocompatibility. Lately, silicon-based glass-ceramics have been investigated as a substitution of calcium phosphates. Several members of this collection exhibit high bioactivity, have attractive mechanical strength, and are known to increase cell proliferation, adhesion, and mineralization of extracellular matrix. Moreover, antibacterial properties of some nanostructured bioceramics established significant interests in avoiding implants rejection in surgery and biomedicine.


This book presents the tunable biological characteristics of nanobioceramics and focuses on some challenges in bone tissue engineering and regenerative medicine. Synthetic composite-based materials and scaffolds should be biodegradable, biocompatible and supply sufficient structural aid for cell migration, along with oxygen, waste, and nutrient carriage to accelerate bone regeneration process and remodeling in defects. These properties may be reached by functioning tunable physical features, including absorption rate, degradation rate, modulus, porosity, and swelling by adjustments with the addition of ceramic phases and copolymers as synthetic composite scaffolds. Synthetic bioceramics seek to imitate the natural hydroxyapatite (HA) crystal creation located in bone. These ceramics, particularly calcium phosphates, have exhibited great osteoinductivity, osteoconductivity, and biocompatibility. Lately, silicon-based glass-ceramics have been investigated as a substitution of calcium phosphates. Several members of this collection exhibit high bioactivity, have attractive mechanical strength, and are known to increase cell proliferation, adhesion, and mineralization of extracellular matrix. Moreover, antibacterial properties of some nanostructured bioceramics established significant interests in avoiding implants rejection in surgery and biomedicine.
Erscheint lt. Verlag 30.1.2025
Reihe/Serie Biological and Medical Physics, Biomedical Engineering
Zusatzinfo X, 282 p. 36 illus., 30 illus. in color.
Sprache englisch
Themenwelt Medizin / Pharmazie Pflege
Medizin / Pharmazie Physiotherapie / Ergotherapie Orthopädie
Naturwissenschaften Biologie
Naturwissenschaften Physik / Astronomie Angewandte Physik
Technik Maschinenbau
Technik Medizintechnik
Technik Umwelttechnik / Biotechnologie
Schlagworte Bioactivity and Osteogenic Features • bioglass • biomaterials • Bone Extracellular Matrix (ECM) • Bone Morphogenetic Proteins • Calcium-Magnesium Based Bioceramics • Calcium-Silicate Based Bioceramics • Ceramic-based Composites • Collagenous Proteins • Cytoskeleton Proteins • Nanocomposites • Synthetic Composites
ISBN-10 981-96-0041-3 / 9819600413
ISBN-13 978-981-96-0041-0 / 9789819600410
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