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Fundamentals of Asymmetric Synthesis

G. L. David Krupadanam (Autor)

Buch | Softcover

468 Seiten

2024
CRC Press (Verlag)
978-1-032-96446-1 (ISBN)

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Asymmetric synthesis is an integral part of synthetic organic chemistry. Some of the reactions in this book were known prior to 1980, while several new ones, particularly catalytic asymmetric reactions, have been discovered in the recent years. The impact of this new class of reactions has been impressively extensive—both on organic and medicinal chemistry. These reactions have been accepted whole-heartedly by synthetic organic chemists in developing shorter routes for complex natural targets as well as in the manufacture of a wide range of drug intermediates.

Introduction
Terms, Definitions and Concepts in Asymmetric Synthesis
Achiral and Chiral Molecules and Their Properties
Prochirality
Enantioselective and Diastereoselective Synthesis
Methods for Monitoring Enantioselective and Diastereoselective Synthesis
Methods for Inducing Asymmetry
Chiral Substrate Controlled Asymmetric Reactions: Diastereoselection in acyclic systems
Chiral auxiliary controlled asymmetric reactions—Asymmetric a-alkylations
Chiral Stoichiometric Reagent Controlled Asymmetric Synthesis: Chiral Boron Reagents
Chiral Catalyst Mediated Asymmetric Reactions: Enzymes
Chiral Organometallic Catalysed Asymmetric Reactions: Sharpless Asymmetric Epoxidations, Dihydroxylations and Aminohydroxylations
Chiral Organometallic Catalysed Asymmetric Reactions
Organocatalysts in Asymmetric Synthesis—Chiral Additive Mediated Reactions
Asymmetric Aldol Reaction
Asymmetric Diels–Alder reactions
Stereoselective Synthesis and Stereospecific Synthesis
Index

Erscheinungsdatum	31.01.2025
Verlagsort	London
Sprache	englisch
Maße	175 x 238 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Chemie ► Organische Chemie
ISBN-10	1-032-96446-4 / 1032964464
ISBN-13	978-1-032-96446-1 / 9781032964461
Zustand	Neuware