Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging
Academic Press Inc (Verlag)
978-0-323-90235-9 (ISBN)
Dr. Sandeep Kumar Singh is Assistant Professor in the All India Institute of Medical Sciences (AIIMS), Nagpur, India. He obtained his PhD in Biotechnology from Banaras Hindu University and conducted postdoctoral research in the Department of Neurobiology at the University of Chicago. Dr. Singh brings 17 years of experience in neuroscience, molecular biology, neurodegenerative diseases, aging, nutraceuticals, and nanomedicines. He is a member of several scientific societies, including the American Academy of Neurology, International Society of Neurochemistry, Society of Neurochemistry, Indian Academy of Neurosciences, and Alzheimer’s and related Disorders Society of India. Dr. Singh has published five books, including Elsevier’s A New Era in Alzheimer’s Research and Genome Editing for Neurodegenerative Diseases. Chih-Li Lin is a Professor and Research Fellow of Chung Shan Medical University and Hospital, Taiwan. He obtained his Ph. D. degree in the Institute of Biochemistry and Molecular Biology from National Taiwan University Medical College in 2007. Lin completed his postdoctoral research on the dementia & Alzheimer’s disease in National Taiwan University Hospital, and then moved to Institute of Medicine, Chung Shan Medical University (Taiwan) in 2008 and has been promoted to Full Professor in 2019. His major interests are to understand the pathophysiological connections between brain aging and Alzheimer’s dementia, particularly studying molecular mechanisms of amyloid beta (Aβ)-induced neurotoxicity, and applications of induced pluripotent stem (iPS) cell technology. He is currently working to demonstrate that brain insulin resistance may play roles in neuronal aging features and contribute to pathogenesis of Alzheimer's disease, Dementia with Lewy Bodies (DLB), and type 2 diabetes-associated dementia. Shailendra Kumar Mishra is co-founder of Indian Scientific Education and Technology (ISET) Foundation, a non-profit/non-governmental organization that persuades toward the science promotion. He is Molecular Human Genetics postgraduate, skilled in DNA Sequencing, Polymerase Chain Reaction (PCR), DNA & Plasmid isolation, Gel electrophoresis, Molecular hybridization, DNA elution from agarose gel, bacterial transformation, quantitation of DNA, DNA sequencing technique and versed in various diagnostic techniques. He did Master of Science in Molecular and Human Genetics from Jiwaji University, India, and research project from Banaras Hindu University, India. He has published his articles in some international and national journals such as Journal of Alzheimer’s Disease and Parkinsonism and Nature India. His major interest is to understand the aging process through molecular basis that could be beneficial to cure age-related diseases.
1. The aging: introduction, theories, principles and future prospective
Shabnam Shabir, Mahendra Pratap Singh
2. Brief description of aging in different levels as cellular, tissues, and organs
Anuradha Venkatakrishnan Chimata, Prajakta Deshpande, Amit Singh
3. Brief about hallmarks of aging
Josephine Esposto and Vyshnavy Balendra
4. Overview of various anti-aging strategies
Dhiraj Kumar and Faiyaz Ahmad
5. Elimination of damaged cells-dependent anti-aging strategy
Rayees Ahmad Naik, Vinodinee Dubey, Roshni Rajpoot, Debabrata Dash, Nidhi Gupta and Raj Kumar Koiri
6. Telomerase reactivation for anti-aging
TS Gopenath, Shreya Shreshtha and Kanthesh M. Basalingapa
7. Epigenetic drugs based on anti-aging approach
Tarun Minocha, Namrata Dwivedi, Chetan Panda, Anamika Misra, Barsha Baisakhi Nayak, Sanjeev Kumar Yadav, Hareram Birla and Sandeep K. Singh
8. Activation of chaperons and proteolytic system: emerging methods for anti-aging drug development
Neha Gogia, Victor Olmos, Fatema Haidery, Kimberly Luttik, Leon Tejwani, Janghoo Lim
9. Dietary restriction and mTOR and IIS inhibition: the potential to anti-aging drug approach
Sing-Hua Tsou
10. Anti-Aging Drugs, Candidates, and Food Supplements- The journey so far
Yodhaanjali JR, Rithwick Surya, Sumukha KC, Harini G, Gouri Deshpande, Chandan S,Raghu Ram Achar
11. Role of AMPK and Sirtuins as anti-aging proteins
Manjula Ramu, Sonali Vishal and Neha Gogia
12. Mitophagy and Mitohormetics: promising anti- aging strategy
Chih Li Lin
13. Clearance of senescent cells: potent anti-aging approach
Jacques Ferreira and Alex Deamer
14. Stem cell-based therapy as antiaging prospective
Sumaira Yusuf, Mahendra P. Singh
15. Anti-inflammatory therapy as a game changer towards anti-aging
Dr. Naveen Shivavedi, Anshul Shakya, Bedanta Bhattacharjee and Bhargab Deka
16. Invertebrate model organisms for aging research
Arvind Kumar Shukla, Andrew Scott and Edward Giniger
| Erscheinungsdatum | 08.06.2022 |
|---|---|
| Zusatzinfo | 60 illustrations (10 in full color); Illustrations |
| Verlagsort | Oxford |
| Sprache | englisch |
| Maße | 191 x 235 mm |
| Gewicht | 810 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Geriatrie |
| Medizinische Fachgebiete ► Innere Medizin ► Diabetologie | |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie | |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie | |
| ISBN-10 | 0-323-90235-9 / 0323902359 |
| ISBN-13 | 978-0-323-90235-9 / 9780323902359 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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