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Phytonutrients and Neurological Disorders

Therapeutic and Toxicological Aspects

Haroon Khan, Michael Aschner, Hamed Mirzaei (Herausgeber)

Buch | Softcover

416 Seiten

2023
Academic Press Inc (Verlag)
978-0-12-824467-8 (ISBN)

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Phytonutrients and Neurological Disorders: Therapeutic and Toxicological Aspects provides and assesses the latest research and developments surrounding the use of phytonutrients for the treatment of neurological disorders. The volume analyzes advances in phytonutrient isolation, characterization and therapeutic applications, giving particular emphasis to mechanisms and safety profiles. The book takes toxicological considerations into account, including adverse drug reactions, toxicokinetics and toxicodynamics. Sections cover bioactive compound classes and biosynthesis pathways, general considerations, including quality control, standardization, and technology, and toxicology. This title is a comprehensive work on the latest research in phytonutrients and neurological disorders that will be useful to researchers and medical practitioners.

Prof. Dr. Haroon Khan has obtained the degree of B. Pharm (1999), M. Phil (2005), and PhD (2011) from the Department of Pharmacy, University of Peshawar. He started his career as a lecturer from the Gandhara College of Pharmacy, Gandhara University, Peshawar and currently, Professor of Pharmacy at the Department of Pharmacy, Abdul Wali Khan University Mardan, Pakistan. He has more than seventeen years of experience in pharmacy teaching, research and professional expertise in various fields of pharmaceutical sciences. Dr. Khan has 162 publications, including research, review, and editorial in various national and international reputable journals with considerable impact factor while several others are submitted or in the process of submission. His research focus is phytomedicines including phytopharmacological and phytochemical investigations of extracts/isolated compounds in collaboration with numerous national and international research groups. The scientific contribution of Dr. Khan has been acknowledged by the Pakistan Council for Science and Pakistan Council for Science and Technology (PCST) and awarded Research Productivity four times 2011-2014. He has also published three books with LAMBERT Academic publishers, Germany and four chapters. He is also the editorial board member of various international journals. Additionally, he is supervising many post-graduate scholars in various research projects. Dr. Michael Aschner is currently the Harold and Muriel Block Chair in Molecular Pharmacology at Albert Einstein College of Medicine where he is also a Professor in the Departments of Molecular Pharmacology, Neuroscience, and Pediatrics. He is a leading expert in neurotoxicology and neurodevelopmental and neurodegenerative diseases. In addition to serving as a past president of the Society of Toxicology (2022-23), he served on numerous toxicology panels (U.S. EPA and CDC), been an expert reviewer for multiple federal agencies in the US and abroad, and is a member of the Neurotoxicology and Alcohol study section (NIH). He is a past recipient of the prestigious Society of Toxicology Merit Award (2010) and the Distinguished Neurotoxicologist Award (2020). He is a co-editor of the Elsevier series, Advancements in Neurotoxicology in addition to edited other Elsevier titles. He has published numerous articles and has served as an associate editor for multiple high impact factor journals. Hamed Mirzaei is a Professor at the Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Iran.

Part A, Section 1: Bioactive compound classes and biosynthesis pathway
1. Current therapies for neurological disorders and their limitations
2. Biosynthesis of phytonutrients
3. Neuroprotective effects of flavonoids
4. Neuroprotective effects of glycosides
5. Neuroprotective effects of terpenoids
6. Neuroprotective effects of alkaloids
7. Neuroprotective effects of saponins
8. Neuroprotective effects of steroids
9. Neuroprotective effects of essential oils
10. Neuroprotective effects of phytonutrients at gene levels

Part A Section 2: General considerations
11. Latest development in quality control parameters/specification in phytonutrients studies
12. Phytonutrients standardization for effective therapeutic outcomes
13. Phytonutrients and technological development in formulations

Part B Sections: Toxicological considerations in phytonutrients
a. Adverse drug reactions
b. Toxicokinetics
c. Toxicodynamics

Erscheinungsdatum	10.07.2023
Zusatzinfo	40 illustrations (20 in full color); Illustrations
Verlagsort	San Diego
Sprache	englisch
Maße	191 x 235 mm
Gewicht	450 g
Themenwelt	Medizin / Pharmazie ► Gesundheitsfachberufe ► Diätassistenz / Ernährungsberatung
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
ISBN-10	0-12-824467-4 / 0128244674
ISBN-13	978-0-12-824467-8 / 9780128244678
Zustand	Neuware