The Cardiovascular System at a Glance (eBook)

Philip I. Aaronson, Jeremy P. T. Ward, Michelle J. Connolly (Autoren)

eBook Download: EPUB

2020 | 5. Auflage
John Wiley & Sons (Verlag)
9781119245766 (ISBN)

Infos

Everything you need to know about the cardiovascular system... at a Glance!

The Cardiovascular System at a Glance is the essential reference guide to understanding all things circulatory. Concise, accessible, and highly illustrated, this latest edition presents an integrated overview of the subject, from the basics through to application. Featuring brand new content on stroke, examination and imaging, heart block and ECGs, and myopathies and channelopathies, The Cardiovascular System at a Glance goes one step further and offers new and updated clinical case studies and multiple-choice questions on a supplementary website.

• Integrates basic science and clinical topics
• Offers bite-size chapters that make topics easy to digest
• Includes coverage of anatomy and histology, blood and haemostasis, cellular physiology, form and function, regulation and integration of cardiovascular function, history, examination and investigations, pathology and therapeutics
• Filled with highly visual, colour illustrations that enhance the text and help reinforce learning

The fifth edition of The Cardiovascular System at a Glance is an ideal resource for medical students, junior doctors, students of other health professions, and specialist cardiology nurses.

Philip I. Aaronson, BA, PhD is Reader in Pharmacology and Therapeutics at King's College, London.

Jeremy P. T. Ward, BSc, PhD, FPhysiol is Emeritus Professor of Physiology at King's College, London.

Michelle J. Connolly, BSc, MBBS, PhD, MRCP is a ST6 Interventional Cardiology Fellow, St George's Hospital, London.

Inhalt

Preface vii

Recommended reading viii

Sources of illustrations ix

Acknowledgements x

List of abbreviations xi

About the companion website xiii

Introduction 1

1 Overview of the cardiovascular system 2

Anatomy and histology 5

2 Gross anatomy and histology of the heart 6

3 Vascular anatomy 8

4 Vascular histology and smooth muscle cell ultrastructure 10

Blood and body fluids 13

5 Constituents of blood 14

6 Erythropoiesis, haemoglobin and anaemia 16

7 Haemostasis 18

8 Thrombosis and anticoagulants 20

9 Blood groups and transfusions 22

Cellular physiology 25

10 Membrane potential, ion channels and pumps 26

11 Electrophysiology of cardiac muscle and origin of the heartbeat 28

12 Cardiac muscle excitation-contraction coupling 30

13 Electrical conduction system in the heart 32

14 The electrocardiogram 34

15 Vascular smooth muscle excitation-contraction coupling 36

Form and function 39

16 Cardiac cycle 40

17 Control of cardiac output 42

18 Haemodynamics 44

19 Blood pressure and flow in the arteries and arterioles 46

20 The microcirculation and lymphatic system and diapedesis 48

21 Fluid filtration in the microcirculation 50

22 The venous system 52

23 Local control of blood flow 54

24 Regulation of the vasculature by the endothelium 56

25 The pulmonary, skeletal muscle and fetal circulations 58

26 The coronary, cutaneous and cerebral circulations 60

Integration and regulation 63

27 Cardiovascular reflexes 64

28 Autonomic control of the cardiovascular system 66

29 The control of blood volume 68

30 Cardiovascular effects of exercise 70

31 Shock and haemorrhage 72

History, examination and investigations 75

32 History and examination of the cardiovascular system 76

33 Cardiac imaging 78

Pathology and therapeutics 81

34 Risk factors for cardiovascular disease 82

35 beta-blockers, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers and Ca¯2+ channel blockers 84

36 Hyperlipidaemias 86

37 Atherosclerosis 88

38 Mechanisms of primary hypertension 90

39 Treatment of hypertension 92

40 Stable, microvascular, and vasospastic angina 94

41 Pharmacological management of stable, microvascular and vasospastic angina 96

42 Non-ST segment elevation acute coronary syndromes (NSTE-ACS) 98

43 Coronary revascularisation 100

44 Pathophysiology of acute myocardial infarction 102

45 ST segment elevation myocardial infarction (STEMI) 104

46 Heart failure 106

47 Treatment of chronic heart failure 108

48 Mechanisms of tachyarrhythmia 112

49 Atrial fibrillation 114

50 Other supraventricular arrhythmias 118

51 Ventricular tachyarrhythmias and their non-pharmacological management 120

52 Pharmacological treatment of tachyarrhythmias 122

53 Conduction system abnormalities and pacing 124

54 Diseases of the aortic valve 126

55 Diseases of the mitral valve 128

56 Congenital heart disease 130

57 Cardiomyopathies and channelopathies 132

58 Pulmonary hypertension 134

59 Stroke 136

Index 139

Textauszug

List of abbreviations

5‐HT

5‐hydroxytryptamine (serotonin)

AAA

abdominal aortic aneurysm

ABP

arterial blood pressure

AC

adenylate cyclase

ACE

angiotensin‐converting enzyme

ACEI

angiotensin‐converting enzyme inhibitor/s

ACS

acute coronary syndromes

ADH

antidiuretic hormone

ADMA

asymmetrical dimethyl arginine

ADP

adenosine diphosphate

AF

atrial fibrillation

AMP

adenosine monophosphate

ANP

atrial natriuretic peptide

ANS

autonomic nervous system

AP

action potential

APAH

pulmonary hypertension associated with other conditions

APC

active protein C

APD

action potential duration

aPTT

activated partial thromboplastin time

AR

aortic regurgitation

ARB

angiotensin 2 receptor blocker

ARDS

acute respiratory distress syndrome

AS

aortic stenosis

ASD

atrial septal defect

ATP

adenosine triphosphate

AV

atrioventricular

AVA

arteriovenous anastomosis

AVN

atrioventricular node

AVNRT

atrioventricular nodal re‐entrant tachycardia

AVRT

atrioventricular re‐entrant tachycardia

AVSD

Atrioventricular septal defects

BBB

blood–brain barrier

BP

blood pressure

CABG

coronary artery bypass grafting

CAD

coronary artery disease

CaM

calmodulin

cAMP

cyclic adenosine monophosphate

CCB

calcium‐channel blocker

CE

cholesteryl ester

CETP

cholesteryl ester transfer protein

CFU‐E

colony‐forming unit erythroid cell

cGMP

cyclic guanosine monophosphate

CHB

omplete heart block

CHD

congenital heart disease

CHD

coronary heart disease

CHF

chronic heart failure

CICR

calcium‐induced calcium release

CK‐MB

creatine kinase MB

CMR

cardiac magnetic resonance imaging

CNS

central nervous system

CO

cardiac output

COPD

chronic obstructive pulmonary disease

COX

cyclooxygenase

CPVT

catecholaminergic polymorphic ventricular tachycardia

CRP

C‐reactive protein

CSF

cerebrospinal fluid

CT

computed tomography

CTPA

computed tomography pulmonary angiogram

CVD

cardiovascular disease

CVP

central venous pressure

CXR

chest X‐ray

DAD

delayed afterdepolarization

DAG

diacylglycerol

DAPT

dual antiplatelet therapy

DBP

diastolic blood pressure

DC

direct current

DCM

dilated cardiomyopathy

DCCV

direct current cardioversion

DHP

dihydropyridine

DIC

disseminated intravascular coagulation

DM2

type 2 diabetes mellitus

DSE

dobutamine stress echocardiography

DVT

deep venous/vein thrombosis

EAD

early afterdepolarization

ECF

extracellular fluid

ECG

electrocardiogram/electrocardiograph (EKG)

ECM

extracellular matrix

EDHF

endothelium‐derived hyperpolarizing factor

EDP

end‐diastolic pressure

EDRF

endothelium‐derived relaxing factor

EDTA

ethylenediaminetetraacetic acid

EDV

end‐diastolic volume

EET

epoxyeicosatrienoic acid

EnaC

epithelial sodium channel

eNOS

endothelial NOS

ERP

effective refractory period

ESR

erythrocyte sedimentation rate

FDP

fibrin degradation product

GP

glycoprotein

GPI

glycoprotein inhibitor

GTN

glyceryl trinitrate

Hb

haemoglobin

HCM

hypertrophic cardiomyopathy

HDL

high‐density lipoprotein

HEET

hydroxyeicosatetraenoic acid

HMG‐CoA

hydroxy‐methylglutanyl coenzyme A

hPAH

heritable pulmonary arterial hypertension

HPV

hypoxic pulmonary vasoconstriction

HR

heart rate

IABP

intra‐aortic balloon pump

ICD

implantable cardioverter defibrillator

IDL

intermediate‐density lipoprotein

Ig

immunoglobulin

IML

intermediolateral

iNOS

inducible NOS

INR

international normalized ratio

IP3

inisotol 1,4,5‐triphosphate

iPAH

idiopathic pulmonary arterial hypertension

ISH

isolated systolic hypertension

IVUS

intravascular ultrasound

JVP

jugular venous pressure

LA

left atrium

LBBB

left bundle branch block

LDL

low‐density lipoprotein

LITA

left internal thoracic artery

LMWH

low molecular weight heparin

L‐NAME

L‐nitro arginine methyl ester

LPL

lipoprotein lipase

LQT

long QT

LV

left ventricle/left ventricular

LVAD

left ventricular assist device

LVH

left ventricular...

Produkt-Details

• Erscheint lt. Verlag: 25.3.2020
• Reihe/Serie: At a Glance
• Reihe/Serie: At a Glance
• Reihe/Serie: At a Glance
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete
• Schlagworte: Allgemeine u. Innere Medizin • Blood • blood groups • Blood vessels • Cardiac cycle • Cardiovascular Disease • cardiovascular disease</p> • Cardiovascular System • ecg • General & Internal Medicine • Gross anatomy • heart • Histology • human body • Kardiovaskuläre Erkrankung • Kardiovaskuläre Erkrankungen • life support • <p>cardiology • Medical • medical guide • Medical Science • Medizin • Physiologie • Physiology • stroke • Vascular anatomy
• ISBN-13: 9781119245766 / 9781119245766