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Lecture Notes (eBook)

Human Physiology

Ole H. Petersen (Herausgeber)

eBook Download: EPUB
2019 | 5. Auflage
John Wiley & Sons (Verlag)
9781119648352 (ISBN)

Lese- und Medienproben

Lecture Notes -
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Lecture Notes: Human Physiology provides concise coverage of general physiology for medical students as well as students of biological sciences, sport science, pharmacology and nursing.

This fifth edition of the ever popular Lecture Notes: Human Physiology has been thoroughly revised and updated by a new international team of authors. The simple structure and systems-based approach remain, with a new clean layout for ease of reading and colour now incorporated to aid understanding.

Lecture Notes: Human Physiology:


  • Provides more focus on pathophysiology for clinical relevance
  • Is the perfect introduction for medical and allied health care students
  • Now includes physiology of pain and increased coverage of heart and the vascular system
  • Includes a completely revised chapter on the nervous system.


Ole H. Peteresen Vice-President of The Royal Society; MRC Research Professor; George Holt Professor of Physiology, University of Liverpool, UK
Lecture Notes: Human Physiology provides concise coverage of general physiology for medical students as well as students of biological sciences, sport science, pharmacology and nursing. This fifth edition of the ever popular Lecture Notes: Human Physiology has been thoroughly revised and updated by a new international team of authors. The simple structure and systems-based approach remain, with a new clean layout for ease of reading and colour now incorporated to aid understanding. Lecture Notes: Human Physiology: Provides more focus on pathophysiology for clinical relevance Is the perfect introduction for medical and allied health care students Now includes physiology of pain and increased coverage of heart and the vascular system Includes a completely revised chapter on the nervous system.

Ole H. Peteresen Vice-President of The Royal Society; MRC Research Professor; George Holt Professor of Physiology, University of Liverpool, UK

Contributors vi

Preface ix

List of Abbreviations x

1 Cell Physiology 1

2 Cellular Communication 22

3 Introduction to the Nervous System 37

4 Signalling in the Nervous System 63

5 Muscle 95

6 Sensory Systems 122

7 Special Senses 138

8 Motor System 185

9 Higher Nervous Functions 213

10 Pain 227

11 Endocrine System 239

12 Reproduction 271

13 Blood 290

14 Introduction to the Cardiovascular System 326

15 Cardiovascular System--The Heart 335

16 Vascular System 372

17 Cardiovascular Regulation Regional Circulation and Circulatory Adjustments 402

18 Respiration 425

19 Digestive System 494

20 Kidney 540

21 Fluid and Electrolyte Balance 570

22 Energy Metabolism 591

23 Temperature Regulation 603

24 Exercise 616

Appendix 1: Units of measurement 623

Appendix 2: Basic Concepts of Acid-Base Chemistry 625

Index 628

"A practical, easy-to-read text that incorporates diagrams
alongside text to aid understanding. Concise and to the point, it
serves as an ideal student text." Medical Student,
Peninsula

"A thoroughly informative and useful anthology of human
physiology, perfectly suited to medical and scientific students
alike, who are looking for a core text with which to edify their
understanding. It will bring physiology alive to you by exploring
the systems in a clear and compelling manner." Medical
Student, Imperial

"The text covers important concepts in physiology, both at
the organ system and cellular levels. It stresses essential and
relevant content with clarity and includes numerous tables and
illustrations." Medical Student, Bristol
University

"Petersen's Human Physiology is 650 pages of excellently
presented, readable science. It is suitable for medical and
undergraduate life science students. Extraneous details are kept to
a minimum, and the text would cover any medical school curriculum."
Medical Student, Dundee University

"Physiology is not easy at the best of times; this book
covers in detail all you need to know in an easy to understand
manner- giving you the basic ground knowledge to form your clinical
knowledge on top." Medical Student, HYMS

"Includes none of the clutter you have to wade through in other
books. The content is condensed down to the essential information
and is presented in a very readable layout. Excellent for
consolidating your learning. Compact yet comprehensive." Medical
Student, Brighton Sussex Medical School

List of Abbreviations


AC
adenylyl cyclase
ACE
angiotensin converting enzyme
ACh
acetylcholine
ACTH
adrenocorticotrophic hormone
ADH
antidiuretic hormone
ADP
adenosine diphosphate
Adr
adrenaline
AEA
arachydonoyl ethanolamide
2-AG
2-arachydonoylglycerol
AIDS
acquired immunodeficiency syndrome
γ-ALA
δ-aminolaevulinic acid
AMP
adenosine monophosphate
AMPA
α-amino-3-hydroxy-5-methyl-isoxazolepropionic acid
ANP
atrial natriuretic peptide
AP
action potential
APC
Adenomatous polyposis coli
APUD
amine precursor uptake and decarboxylation
ARP
absolute refractory period
ASBT
apical sodium-dependent bile transporter
ASIC
acid-sensing ion channel
AT-I
anti-thrombin I
ATP
adenosine triphosphate
ATPS
ambient temperature, pressure, saturated with water
a–v
arterio-venous
AV
atrioventricular
AVP
arginine vasopressin
BAT
brown adipose tissue
BC
basket cell
BDNF
brain-derived neurotrophic factor
BFGF
basic fibroblast growth factor
BMI
body mass index
BMR
basal metabolic rate
BNP
brain natriuretic peptide
Bötz C
Bötzinger complex
2,3-BPG
2,3-bisphosphoglycerate
BTPS
body temperature, pressure, saturated with water
c.a.
carbonic anhydrase
[Ca2+]i
cytosolic free calcium concentration
CaM
calmodulin
cAMP
cyclic adenosine monophosphate
CBF
cerebral blood flow
CCK
cholecystokinin
CD
Crohn’s disease
cf
climbing fibre
CFTR
cystic fibrosis transmembrane conductance regulator
CFU
colony-forming unit
CG
chorionic gonadotrophin
cGMP
cyclic guanosine monophosphate
CGRP
calcitonin gene-related peptide
CHF
congestive heart failure
CICR
calcium-induced calcium release
CNS
central nervous system
CO
carbon monoxide
COMT
catechol O-methyltransferase
COX
cyclooxygenase
CP
creatine phosphate
cPAG
caudal periaqueductal grey
CPD
citrate–phosphate–dextrose
CPG
central pattern generator
CPK
creatine phosphokinase
CREB
cAMP response-element-binding protein
CRH
corticotrophin-releasing hormone
CS
chorionic somatomammotrophin
CSA
central sleep apnoea
CSF
cerebrospinal fluid
CSF
colony-stimulating factor
CVLM
caudal ventrolateral medulla
Cx
connexin
DAG
diacylglycerol
DH
dorsal horn
1,25-DHCC
1,25-dihydroxycholecalciferol (calcitriol)
DHP
dihydropyridine
DIT
di-iodotyrosine
DMH
dorsomedial hypothalamus
DMT1
divalent metal transporter type 1
DOC
11-deoxycorticosterone
L-DOPA
L-dihydroxyphenylalanine
DRG
dorsal respiratory group
DRG
dorsal root ganglion
DTH
delayed-type hypersensitivity
EC
enterochromaffin
ECC
excitation-contraction coupling
ECF
extracellular fluid
ECG
electrocardiogram
ECL
enterochromaffin-like
ECT
electroconvulsive shock therapy
EDHF
endothelium-derived hyperpolarizing factor
EDRF
endothelium-derived relaxing factor
EDTA
ethylenediamine tetra-acetic acid
EEG
electroencephalogram
EGF
epidermal growth factor
EJP
excitatory junction potential
ELISA
enzyme-linked immunosorbent assay
EMG
electromyogram
ENaC
epithelial sodium channel
EOG
electro-oculogram
EPSP
excitatory postsynaptic potential
ER
endoplasmic reticulum
ERV
expiratory reserve volume
ET-1
endothelin 1
exp
expiration
FAAH
fatty acid amide hydrolase
FABP
fatty acid-binding protein
FADH2
flavin adenine dinucleotide (reduced)
FATP
fatty-acid transporter protein
FEF
forced expiratory flow (rate)
FEV1
forced expiratory volume in 1s
fMRI
functional magnetic resonance imaging
FRC
functional residual capacity
FSH
follicle-stimulating hormone
FVC
forced vital capacity
G protein
GTP-regulatory protein
G17, G34
amino acid chain lengths of gastrin
GABA
γ-aminobutyric acid
GAP
GTPase-activating factor
GDP
guanosine diphosphate
GEF
GDP–GTP exchange factor
GEMM
granulocyte, erythroid, monocyte and megakaryocyte
GFAP
glial fibrillary acidic protein
GFR
glomerular filtration rate
GH
growth hormone
GHRH
growth hormone-releasing hormone
GI
gastrointestinal
GIP
gastric inhibitory peptide
GIP
glucose-dependent insulinotropic polypeptide
GL
galanin
GLP
glucagon-like peptide
GLP-1
glucagon-like peptide-1
GLUT2
glucose transporter type 2
GLUT5
glucose transporter type 5
GnRH
gonadotrophin-releasing hormone
GoC
Golgi cell
GORD
gastro-oesophageal reflux disease
GPCR
G-protein coupled receptor
GrC
granule cell
GRP
gastrin-releasing peptide
GTP
guanosine triphosphate
H. pylori
Helicobacter pylori
H2O2
hydrogen peroxide
Hb
haemoglobin
HCG
human chorionic gonadotrophin
HCl
hydrochloric acid
HIV
human immunodeficiency virus
HLA
human leukocyte antigen
HMM
heavy meromyosin
HMWK
high molecular weight kininogen
11b-HSD-2
11β-hydroxy steroid dehydrogenase
5-HT
5-hydroxytryptamine, serotonin
ib,Na
background sodium current
IBD
inflammatory bowel disease
IBS
inflammatory bowel syndrome
IC
inspiratory capacity
iCa,L
L-type (long-lasting) calcium current
iCa,T
T-type (transient) calcium current
ICC
interstitial cell of Cajal
ICF
intracellular fluid
ICSI
intracytoplasmic sperm injection
IDDM
insulin-dependent diabetes mellitus
if
‘funny’ hyperpolarization-activated inward current
Ig
immunoglobulin
IgA
immunoglobulin A
IgD
immunoglobulin D
IgE
immunoglobulin E
IGF
insulin-like growth factor
IgG
mmunoglobulin G
IgM
immunoglobulin M
IJP
inhibitory junction potential
iK
delayed rectifying potassium current
iK1
inward rectifying potassium current
IML
intermediolateral cell column
iNa
fast sodium current
iNCX
sodium-calcium exchanger current
INR
international normalized ratio
Ins-1
insulin substrate-1
insp
inspiration
IP3
inositol 1,4,5-trisphosphate
IPAN
intrinsic primary afferent neurone
IPSP
inhibitory postsynaptic...

Erscheint lt. Verlag 28.6.2019
Sprache englisch
Themenwelt Medizin / Pharmazie Pflege
Studium 1. Studienabschnitt (Vorklinik) Physiologie
Schlagworte accessible • Approach • Cardiovascular • clear • Edition • Fifth • Human • Incorporated • international • Krankenpflege • Layout • Lecture • Material • New • new clean • nononsense approach • nursing • Practical • presentation • restructured • System • Team • Understanding
ISBN-13 9781119648352 / 9781119648352
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