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Vitiligo (eBook)

Medical and Surgical Management
eBook Download: EPUB
2018
John Wiley & Sons (Verlag)
9781118937358 (ISBN)

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Practical guidance based on expert experience and evidence for developing management strategies for vitiligo 

This complete guide to vitiligo provides a full appraisal of strategy for the treatment of this autoimmune disease that affects 1-2% of the world's population. It addresses all aspects of vitiligo, covering the science, medical and surgical therapies, and the psychological evaluations and approaches based on the proper understanding of the causes and classification of a particular case.

Management of vitiligo is challenging and requires a multipronged approach. Vitiligo: Medical and Surgical Management is a comprehensive, timely, state-of-the-art resource that will help those involved with affected patients better understand and treat this disease, which takes its toll on the mental wellness of those afflicted by it. It takes an evidenced-based approach to the disease's treatment; provides an overview of the surgical management; covers tissue and cellular grafting; and more. 

  • Thoroughly guides those involved in the clinical aspects of vitiligo
  • Aids diagnosis and classification of severity
  • Balances evidence and experience
  • Compiled by world-leading expert editors

Comprehensive in nature, Vitiligo: Medical and Surgical Management contains a strong practical element, and is a welcome go-to source for practicing dermatologists and those training to become a dermatologist.



About the Editors

Somesh Gupta, MD, DNB, MNAMS, Professor, Department of Dermatology & Venereology, All India Institute of Medical Sciences, New Delhi, India

Mats J. Olsson, MD, PhD, CEO, ParkCell AB and President, International Vitiligo Center, Uppsala, Sweden

Davinder Parsad, MD, Professor, Department of Dermatology, Venereology & Leprology, Postgraduate Institute of Medical Education & Research, Chandigarh, India

Henry W. Lim, MD, Chair Emeritus, Department of Dermatology and Senior Vice President for Academic Affairs, Henry Ford Health System. Past President, American Academy of Dermatology, Detroit, USA

Nanja van Geel, MD, PhD, Professor, Department of Dermatology, Ghent University Hospital, Ghent, Belgium

Amit G. Pandya, MD, Professor, Department of Dermatology, University of Texas, Southwestern Medical Center, Dallas, USA


Practical guidance based on expert experience and evidence for developing management strategies for vitiligo This complete guide to vitiligo provides a full appraisal of strategy for the treatment of this autoimmune disease that affects 1-2% of the world s population. It addresses all aspects of vitiligo, covering the science, medical and surgical therapies, and the psychological evaluations and approaches based on the proper understanding of the causes and classification of a particular case. Management of vitiligo is challenging and requires a multipronged approach. Vitiligo: Medical and Surgical Management is a comprehensive, timely, state-of-the-art resource that will help those involved with affected patients better understand and treat this disease, which takes its toll on the mental wellness of those afflicted by it. It takes an evidenced-based approach to the disease s treatment; provides an overview of the surgical management; covers tissue and cellular grafting; and more. Thoroughly guides those involved in the clinical aspects of vitiligo Aids diagnosis and classification of severity Balances evidence and experience Compiled by world-leading expert editors Comprehensive in nature, Vitiligo: Medical and Surgical Management contains a strong practical element, and is a welcome go-to source for practicing dermatologists and those training to become a dermatologist.

About the Editors Somesh Gupta, MD, DNB, MNAMS, Professor, Department of Dermatology & Venereology, All India Institute of Medical Sciences, New Delhi, India Mats J. Olsson, MD, PhD, CEO, ParkCell AB and President, International Vitiligo Center, Uppsala, Sweden Davinder Parsad, MD, Professor, Department of Dermatology, Venereology & Leprology, Postgraduate Institute of Medical Education & Research, Chandigarh, India Henry W. Lim, MD, Chair Emeritus, Department of Dermatology and Senior Vice President for Academic Affairs, Henry Ford Health System. Past President, American Academy of Dermatology, Detroit, USA Nanja van Geel, MD, PhD, Professor, Department of Dermatology, Ghent University Hospital, Ghent, Belgium Amit G. Pandya, MD, Professor, Department of Dermatology, University of Texas, Southwestern Medical Center, Dallas, USA

Table of Contents

List of Contributors

1 Introduction

2 Melanocyte and melanogenesis: Applied anatomy and physiology

3 Epidemiology of Vitiligo

4 Pathogenesis of vitiligo

5 Understanding the mechanisms of repigmentation in vitiligo

6 Classification and Clinical Features of vitiligo

7 Outcome Measures for Vitiligo

8 Evaluation and treatment of the psychosocial burden of vitiligo

9 Patient support, education and compliance

10 Goals of Vitiligo Treatment, and Evidence Based Practice Guidelines for Medical and Surgical Management

11 The concept of stability of vitiligo and stabilization therapies

12 Narrowband Ultraviolet B Phototherapy in Vitiligo

13 UVA-based Phototherapy: PUVA, PUVA-sol, UVA1 phototherapy

14 Immunomodulators and immunosuppressives in Vitiligo

15 Topical Glucocorticoids, Topical Calcineurin Inhibitors and Topical Vitamin D3 Analogues

16 Targeted Phototherapy in Vitiligo

17 OTHER THERAPIES IN VITILIGO

18 Biologic therapies for vitiligo

19 Evidence toward integrated management of Vitiligo combining Ayurveda and Homeopathy with Modern Dermatology

20 History and chronology of development of surgical therapies for vitiligo

21 Patient selection, pre and postoperative information in surgical therapies for vitiligo

22 Classification of surgical therapies for vitiligo

23 Minigrafting for vitiligo

24 Suction blister epidermal grafting

25 Thin and ultra-thin skin grafts for vitiligo

26 Treatment of leukoderma by transplantation of ultra-thin epidermal sheets

27 Surgical management of leukotrichia

28 Mesh grafting in vitiligo

29 Smash Grafting

30 Therapeutic Needling and Needling Micrografting

31 Complications and limitations of melanocyte transplantation

32 Treatment of leukoderma by transplantation of basal cell layer suspension

33 Non cultured extracted follicle outer root sheath cell suspension transplantation

34 Long term results of non cultured epidermal cellular grafting in vitiligo

35 Simplified Non-Cultured Cellular Grafting

36 Novel methods of preparing epidermal cell suspension for transplantation in vitiligo

37 Setting up a tissue culture laboratory

38 Treatment of leukoderma by transplantation of cultured autologous melanocytes

39 Transplantation of in-vitro cultured epithelial grafts for vitiligo and piebaldism

40 Application of lasers for abrasion in transplantation procedures for vitiligo

41 Cell delivery on recipient skin

42 Safety concerns in transplantation of in vitro cultured cellular grafts

43 Surgical management of lip vitiligo, eyelids and genitals

44 Surgical management of acral vitiligo

45 Surgical management of leukotrichia

46 Surgical treatments of leukodermas other than vitiligo vulgaris

47 Ethnic issues in management and Sun protection

48 Management Issues for Vitiligo in Children and Pregnant Women

49 Combination treatments for Vitiligo

50 Micropigmentation

51 CAMOUFLAGE IN VITILIGO

52 Depigmentation treatment for vitiligo: bleaching cream, laser and cryotherapy

53 Future directions in medical and surgical management of vitiligo

54 Informed consent

List of Contributors


Madhur G. Aggithaya, MD
Institute of Applied Dermatology
Kerala
India

Mohammed Al‐Jamal, MD
Department of Dermatology
Henry Ford Hospital
Detroit
Michigan
USA

Pradeep Balasubramanian, MD
Department of Dermatology
PSG IMSR
Coimbatore
India

Riti Bhatia, MD
Department of Dermatology and Venereology
All India Institute of Medical Sciences,
New Delhi
India

Anuradha Bishnoi, MD
Department of Dermatology
Postgraduate Institute of Medical Education & Research
Chandigarh
India

Laila Benzekri, PhD
Mohammed V University
Ibn Sina Hospital
Department of Dermatology
Rabat
Morocco

Sergio Bondanza, BSc
Laboratory of Tissue Engineering and Cutaneous Physiopathology
Istituto Dermopatico dell’Immacolata, IDI‐IRCCS
Rome
Italy

Barbara Boone, PhD
Department of Dermatology
Ghent University Hospital
Belgium

Kuthaje S. Bose, LECH
Institute of Applied Dermatology
Kerala
India

Gwang Seong Choi, MD, PhD
Department of Dermatology
Inha University College of Medicine
Incheon
Republic of Korea

Sai Yee Chuah, MBChB, MRCP, MRCPS, Diploma in Dermatology
Department of Dermatology
National Skin Centre
Singapore

Rafał Czajkowski, MD, PhD, Prof. NCU
Department of Dermatology
Sexually Transmitted Diseases and Immunodermatology
Ludwik Rydygier Medical College in Bydgoszcz
Nicolaus Copernicus University in Torun
Poland

Elena Dellambra, PhD
Laboratory of Tissue Engineering and Cutaneous Physiopathology
Istituto Dermopatico dell’Immacolata IDI‐IRCCS
Rome
Italy

Sofie De Schepper, MD, PhD
Department of Dermatology
Ghent University Hospital
Belgium

Tomasz Drewa, MD, PhD, FEBU
Department of Urology
Ludwik Rydygier Medical College in Bydgoszcz
Nicolaus Copernicus University in Torun
Poland

Khaled Ezzedine, MD, PhD
EA EpiDermE (Epidémiologie en Dermatologie et Evaluation des Thérapeutiques)
UPE‐Université Paris‐Est
Service de Dermatologie
Hôpital Henri Mondor
France

Jackie Gardner
Vitiligo Support International
Lynchburg
Virginia
USA

Yvon Gauthier, MD
Pigmentary Disorders Outpatient Clinic
Department of Dermatology
Hôpital Saint André
France

James L. Griffith, MD
Department of Dermatology
Henry Ford Hospital
Detroit
Michigan
USA

Pearl E. Grimes, MD, FAAD
Vitiligo and Pigmentation Institute of Southern California
Los Angeles;
Department of Dermatology
University of California, Los Angeles
CA
USA

Liliana Guerra, MD
Laboratory of Tissue Engineering and Cutaneous Physiopathology
Istituto Dermopatico dell’Immacolata, IDI‐IRCCS
Rome
Italy

Sanjeev Gupta, MD
Department of Dermatology and Venereology
Maharishi Markandeshwar Institute of Medical Sciences and Research
Ambala
India

Somesh Gupta, MD, DNB, MNAMS
Department of Dermatology and Venereology
All India Institute of Medical Sciences
New Delhi
India

Vishal Gupta, MD
Department of Dermatology and Venereology
All India Institute of Medical Sciences
New Delhi
India

Iltefat H. Hamzavi, MD, FAAD (Fellow of the American Academy of Dermatology)
Department of Dermatology
Henry Ford Hospital
Michigan
USA

Richard H. Huggins, MD, FAAD (Fellow of the American Academy of Dermatology)
Department of Dermatology
Henry Ford Health System
Detroit
Michigan
USA

Thomas Hunziker, MD
Department of Dermatology
University of Bern
Bern
Switzerland

Seung‐Kyung Hann, MD, PhD
Korea Institute of Vitiligo Research & Drs Woo and Hann’s Skin Center
Seoul
Korea

John E. Harris, MD, PhD
Department of Dermatology
Vitiligo Clinic and Research Center
Worcester MA
USA

Amrinder J. Kanwar, MD
Department of Dermatology
Postgraduate Institute of Medical Education & Research
Chandigarh
India

Sumit Kar, MD
Department of Dermatology, Venereology and Leprosy
MGIMS, Sewagram
Maharashtra
India

Boon Kee Goh, MD, PhD
Pigment Clinic
National Skin Center;
Skin Physicians Private Limited
Mount Elizabeth Medical Centre
Singapore

Ajay Krishnan, MD
Department of Dermatology, Venereology and Leprosy
MGIMS
Wardha
Maharashtra
India

Amrendra Kumar, MD
Dermaclinix
The Complete Skin and Hair Solution Center
New Delhi
India

Ravinder Kumar, PhD
Department of Zoology
Panjab University
Chandigarh
India

Koushik Lahiri, FRCP
Greenwood Nook
Coral Isle
Kolkata
India

Hilde Lapeere, MD, PhD
Department of Dermatology
Ghent University Hospital
Belgium

Henry W. Lim, MD
Department of Dermatology;
Academic Affairs
Henry Ford Health System
American Academy of Dermatology
Detroit, USA

Małgorzata Maj, PhD
Department of Tissue Engineering
Ludwik Rydygier Medical College in Bydgoszcz
Nicolaus Copernicus University in Torun
Poland

Imran Majid, MD (Dermatology and STD)
CUTIS Institute of Dermatology
Srinagar, Kashmi

Saravu R. Narahari, MD
Institute of Applied Dermatology
Kerala
India

Adil A. Noaimi, MD, DDV, FICMS
Department of Dermatology
College of Medicine
University of Baghdad;
Iraqi and Arab Board for Dermatology and Venereology
Baghdad Teaching Hospital
Medical City
Baghdad
Iraq

Ljubomir B. Novaković FRCP
Department of Photodermatology
St John’s Institute of Dermatology
Guy's & St. Thomas’ NHS Trust
London, UK

Sang Ho Oh, MD, PhD
Department of Dermatology
Severance Hospital & Cutaneous Biology Research Institute
Yonsei University College of Medicine
Seoul
Korea

Mats J. Olsson, MD, PhD
International Vitiligo Center
Uppsala, Sweden

Amit G. Pandya, MD
Department of Dermatology
University of Texas Southwestern Medical Center
Dallas
Texas
USA

Davinder Parsad, MD
Department of Dermatology
Venereology & Leprology
Postgraduate Institute of Medical Education & Research
Chandigarh
India

Patrizia Paterna, BSc
Laboratory of Tissue Engineering and Cutaneous Physiopathology
Istituto Dermopatico dell’Immacolata, IDI‐IRCCS
Rome
Italy

Kodimoole S. Prasanna, DVD
Institute of Applied Dermatology
Kerala
India

Reena Rai, MD
PSG Institute of Medical Science & Research
Coimbatore
India

M. Ramam, MD
Department of Dermatology & Venereology
All India Institute of Medical Sciences
New Delhi
India

Desanka Raskovic, MD
VI Division of Dermatology
Istituto Dermopatico dell’Immacolata, IDI‐IRCCS
Rome
Italy

Kanika Sahni, MD
Department of Dermatology and Venereology
All India Institute of Medical Sciences,
New Delhi
India

Khalifa E. Sharquie, MD, PhD
Department of Dermatology
College of Medicine
University of Baghdad;
Iraqi and Arab Board for Dermatology and Venereology
Baghdad Teaching Hospital
Medical City
Baghdad
Iraq

C.K. Shashidharan Nair, PhD
Department of Physics
PSG College of Technology
Coimbatore
India

Narumol Silpa‐archa, MD
Department of Dermatology
Henry Ford Health System
Detroit
Michigan
USA;
Department of Dermatology
Faculty of Medicine Siriraj Hospital
Mahidol University
Bangkok
Thailand

Nanette Silverberg, MD
Mt Sinai St Luke’s‐Roosevelt Hospital Center
New York
USA

Sudhir Singh, MD
Department of Dermatology, Venereology and Leprosy
DMIMSDU
Maharashtra
India

Reinhart Speeckaert, MD, PhD
Department of Dermatology
Ghent University Hospital
Belgium

Chakravarthi R. Srinivas, MD
Department of Dermatology
PSG IMSR
Coimbatore
India

Gurvinder P. Thami, MD
Department of Dermatology
Government Medical College
Chandigarh
India

Monique R.T.M. Thissen, MD, PhD
Department of Dermatology
Maastricht University Medical Centre
Netherlands

Freya Van Driessche, BS
University of Miami
Miller School of Medicine
Miami
FL
USA

Nanja van Geel, MD, PhD
Department of Dermatology
Ghent University Hospital
Ghent,...

Erscheint lt. Verlag 28.2.2018
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Dermatologie
Schlagworte Autoimmune diseases • Cosmetic / Esthetic Dermatology • depigmented skin • dermatologic surgery • Dermatologie • Dermatologische Chirurgie • Dermatology • dermatology conditions • epidermal disease • guide to vitiligo • Kosmetische u. Ästhetische Dermatologie • Medical Science • Medizin • Melanocytes • pigment forming cells • plastic surgery for skin disease • rare skin disorders • Skin • skin conditions • skin diseases • skin pigment • surgical depigmentation • the psychological effects of vitiligo • Venereology • Vitiligo • vitiligo and suicide • Vitiligo: Medical and Surgical Management
ISBN-13 9781118937358 / 9781118937358
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