LC-HR-MS/MS Library of Drugs, Poisons, and Their Metabolites
2018
|
1. Auflage
Wiley-VCH (Hersteller)
978-3-527-34338-6 (ISBN)
Wiley-VCH (Hersteller)
978-3-527-34338-6 (ISBN)
Zu diesem Artikel existiert eine Nachauflage
A major goal in clinical and forensic as well as in doping laboratories is a broad screening procedure for detection of toxic compounds or drugs of abuse. In addition to GC-MS and LC-MSn screening techniques, LC-high-resolution tandem mass spectrometry (LC-HR-MS/MS) provides various advantages for screening approaches such as higher versatility, sensitivity and specificity. The Maurer/Meyer/Helfer/Weber LC-HR-MS/MS Library of Drugs, Poisons, and Their Metabolites is the basis for metabolite-based screening procedures described for various drug classes.
Detection of metabolites increases selectivity, allows confirmation of the body passage, and finally, minimizes the risk of false negative LC-MS results possibly caused by ion suppression of the target analyte. The LC-HR-MS/MS library features over 2,000 parent drugs or poisons, and over 3,000 of their metabolites or artifacts in over 95 compound classification groups.
Data Fields:
Featured Compound Classifications:
Compatibility:
Thermo™ TraceFinder™, NIST MS Search
Detection of metabolites increases selectivity, allows confirmation of the body passage, and finally, minimizes the risk of false negative LC-MS results possibly caused by ion suppression of the target analyte. The LC-HR-MS/MS library features over 2,000 parent drugs or poisons, and over 3,000 of their metabolites or artifacts in over 95 compound classification groups.
Data Fields:
- Compound name
- Empirical formula
- Exact molecular mass in u
- Exact precursor mass
- Five most intensive fragments
- Polarity
- Retention time in min
- CAS number
- Category
Featured Compound Classifications:
- Analgesics
- Anticonvulsants
- Antidiabetics
- Antihypertensives
- Cannabinoids
- Diuretics
- Drugs of Abuse, NPS
- Hypnotics
- Insecticides
- Psychotropics
- Virustatics
- ... and more
Compatibility:
Thermo™ TraceFinder™, NIST MS Search
| Erscheint lt. Verlag | 30.5.2018 |
|---|---|
| Verlagsort | Berlin |
| Sprache | englisch |
| Maße | 139 x 190 mm |
| Gewicht | 82 g |
| Themenwelt | Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie |
| Naturwissenschaften ► Chemie | |
| Schlagworte | Chemie • Chemistry • Massenspektrometrie • Mass Spectrometry • Toxicology • Toxikologie |
| ISBN-10 | 3-527-34338-5 / 3527343385 |
| ISBN-13 | 978-3-527-34338-6 / 9783527343386 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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