Secondary Metabolites from Fungi

Strategies of Activation of Silent Biosynthetic Pathways, Structure Elucidation and Biactivity

Herve Sergi Akone (Autor)

Buch | Softcover

152 Seiten

2017
Südwestdeutscher Verlag für Hochschulschriften
978-3-8381-5355-1 (ISBN)

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Since the discovery of penicillin, fungi stand as an inexhaustible source of novel chemotypes and pharmacophores. A particular interest is given to fungi that are referred to endophytic fungi which are fungi inhabiting internal tissues of plant without causing any visible symptoms of disease. In the past two decades, endophytic fungi have been recognized, as an important source of natural bioactive products with potential application in many areas such as medicine. Since the ''gold" bioactive compound paclitaxel (Taxol®) was discovered from the endophytic fungus Taxomyces andreanae, an increasing interest has been given to the study of fungal endophytes as potential producers of novel and biologically active compounds. However, it appears that the potential of fungal capability to produce bioactive natural compound has been underexplored as only a subset of fungal bioactive compounds is usually obtained under standard laboratory conditions. This book mainly focuses on strategies to increase fungal potential to produce new bioactive compounds through the activation of silent biosynthetic pathways with a particular interest in cytotoxic and antibiotic activities.

Akone, Herve SergiDr. Akone Herve Sergi was born in Edea-Cameroon. He studied in Cameroon where he successfully completed a B.A. in Chemistry, and M.A. in Organic Chemistry. He achieved his PhD. with honors in Germany after a DAAD scholarship. Mr Akone is at present Senior Lecturer at the University of Douala Cameroon and his main research focus on endophytic fungi.

Erscheinungsdatum	09.02.2017
Sprache	englisch
Maße	150 x 220 mm
Gewicht	244 g
Themenwelt	Medizin / Pharmazie ► Pharmazie
Schlagworte	co-culture • Endophytic Fungi • Pharmazie • secondary metabolites
ISBN-10	3-8381-5355-3 / 3838153553
ISBN-13	978-3-8381-5355-1 / 9783838153551
Zustand	Neuware