Advances in Studies on Enzyme Inhibitors as Drugs

Volume 2: Miscellaneous Drugs

Buch | Hardcover

330 Seiten

2017
Nova Science Publishers Inc (Verlag)
978-1-5361-0505-6 (ISBN)

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This book which is edited by eminent scientist Satya P. Gupta, covers the most recent development on design and discovery of the most useful drugs acting against several life threatening diseases such as cancer, viral infections and many others in two volumes. All of these drugs are based on inhibitions of various enzymes. Most human diseases are found to be associated with the overexpression of the enzymes. The book presents the structural aspects of various enzymes, their active sites, and the structural requirements of chemicals for strong interactions with enzymes. Volume One contains twelve chapters related to enzyme inhibitors acting as anticancer and antiviral drugs (each written by highly acclaimed authors), and Volume Two contains ten chapters on enzyme inhibitors acting against miscellaneous diseases written by equally competent authors. The book may be an asset for drug industries, research organisations, and individual researchers.

Preface; Protease Inhibitors as Potential Antimalarial Agents; Enzymatic Targets for Drug Discovery Against Alzheimer's Disease; Design & Development of Some Selective Enzyme Inhibitors for Parkinsons & Alzheimers Diseases Based on Molecular Modeling & Dynamics Studies; Pyruvate Dehydrogenase Kinases (PDHKs) & Their Inhibition: A Possible Line of Treatment for Diabetes, Heart Ischemia & Cancer; Advances in Studies on COX/LOX Enzymes Inhibitors as Drugs; Design & Development of Matrix Metalloproteinase Inhibitors Containing Zinc-Binding Groups, without Zinc-Binding Groups, & Mechanism-Based; Computational Study of D-Amino Acid Oxidase & Its Inhibitors; Cytochrome P450 Inhibitors Used as Drugs; Quantum Chemical Insights into Metabolic Inhibition of Cytochrome P450 Enzymes: Piperine, Curcumin, & Metal Complexes of Curcumin: Promises & Bioavailability; Design & Development of Angiotensin-Converting Enzyme Inhibitors; Index.

Erscheinungsdatum	05.01.2017
Verlagsort	New York
Sprache	englisch
Maße	180 x 260 mm
Gewicht	762 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Pflege
	Medizin / Pharmazie ► Pharmazie ► PTA / PKA
ISBN-10	1-5361-0505-8 / 1536105058
ISBN-13	978-1-5361-0505-6 / 9781536105056
Zustand	Neuware