D1: D2 Dopamine Receptor Interactions
Academic Press Inc (Verlag)
978-0-12-729045-4 (ISBN)
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This volume presents up-to-date comprehensive reviews of neuroscience research and theory on the fundamental interactions between the D1 and D2 dopamine receptor subtypes at numerous levels of investigation-from molecular biology and neuroanatomy, through electrophysiology, to the psychopharmacology of multiple forms of behavior, putative clinical significance, and therapeutic potential. This volume seeks to stand as a reference source on the evolution of the concept of D1: D2 interactions, on their substrates and psychopharmacological roles and, in such a continually evolving field, to look to the future. The Neuroscience Perspectives series aims to provide an all-round view of a current topic of great interest in neuroscience from the biochemical, pharmacological, and physiological standpoints together with the potential therapeutic applications.
Professor Peter Jenner is a specialist in preclinical aspects of neurodegenerative diseases, notably Parkinson’s disease. He has spent the major part of his career at King’s College London where he was Head of Pharmacology for 14 years before returning to his research roots and subsequently becoming Emeritus Professor of Pharmacology. Peter has expertise in drug metabolism and pharmacokinetics but neuropharmacology based on functional models of neurodegenerative diseases has formed the major focus of his work. Peter holds a BPharm, PhD and DSc degree from the University of London. He has published well over 1000 articles with more than 700 peer reviewed papers. He is a Fellow of the Royal Pharmaceutical Society, the British Pharmacological Society, the Royal Society of Medicine and of King’s College London. Peter was recently honoured with a Doctor Honoris Causa degree from Carol Davila University of Medicine and Pharmacy, Bucharest and made an Honorary Fellow of The British Pharmacological Society for his contribution to research in to movement disorders. Peter has worked closely with the pharmaceutical industry for many years and acts as an adviser and consultant to both major pharma and biotech companies. He has a wide knowledge of the drug discovery and drug development process and has been involved from molecule synthesis through to drug registration for use in man. Peter was the Founder, Director and Chief Scientific Officer of Proximagen, a biotech focussed on the treatment and cure of neurodegenerative diseases that was listed on AIMs and subsequently purchased by a US based healthcare company. He is a regular speaker at international meetings and also takes time to speak at Parkinson’s disease patient-carer groups across the UK.
D.R. Sibley, F.J. Monsma, and Y. Shen, Molecular Neurobiology of D1: D2 Dopamine Receptors.
J.N. Joyce, S. Goldsmith, and A.M. Murray, Neuroanatomical Localisation of D1: D2 Receptors: Similar Organisation in the Basal Ganglia of the Rat, Cat and Human, and Disparate Organisation in the Cortex and Limbic System.
J.L. Waddington and S.A. Daly, Regulation of Unconditioned Motor Behaviour by D1: D2 Interactions.
F.J. White and X.-T. Hu, Electrophysiological Correlates of D1: D2 Interactions.
R. Benninger, Role of D1: D2 Receptors in Learning.
E.B. Nielsen Regulation of Drug Discrimination Behaviour by Dopamine D1: D2 Receptors.
E. Ongini, Role of D1: D2 Receptors in the Modulation of States of Arousal and Sleep.
S.J. Cooper and H. Al-Naser, D1: D2 Dopamine Receptor Interactions in Relation to Feeding Responses and Food Intake.
M.S. Starr, Regulation of Seizure Threshold by D1: D2 Receptors.
J.L. Waddington, Future Directions: Clinical Significance and Therapeutic Potential of D1: D2 Interactions in Parkinsons Disease, Schizophrenia and Other Disorders.
Subject Index.
| Erscheint lt. Verlag | 10.6.1993 |
|---|---|
| Reihe/Serie | Neuroscience Perspectives |
| Mitarbeit |
Herausgeber (Serie): Peter Jenner |
| Verlagsort | San Diego |
| Sprache | englisch |
| Gewicht | 550 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Anatomie / Neuroanatomie | |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| Naturwissenschaften ► Biologie ► Humanbiologie | |
| Naturwissenschaften ► Biologie ► Zoologie | |
| ISBN-10 | 0-12-729045-1 / 0127290451 |
| ISBN-13 | 978-0-12-729045-4 / 9780127290454 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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