DNA Methylation

Patterns, Functions & Roles in Disease

Buch | Hardcover

205 Seiten

2016
Nova Science Publishers Inc (Verlag)
978-1-5361-0244-4 (ISBN)

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This book provides new research on the patterns, functions and roles in disease of DNA methylation. Chapter One studies the disruption of DNA methylation patterns caused by exposure to environmental factors during the developmental period. Chapter Two presents transcriptional regulation by cytosine modifications through a broad concept of molecular sciences in physics, chemistry and biology, and suggests a complex network for cytosine modifications-mediated transcription depending on multiple factors. Chapter Three reviews the loss of Insulin-like growth factor 2 (IGF2) imprinting in human tumors, focusing especially on the mechanisms underlying this abnormality in epigenetic control; and summarizes recent progress on targeting this tumor specific imprinting abnormality as a novel anti-cancer approach.

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Erscheinungsdatum	03.12.2016
Verlagsort	New York
Sprache	englisch
Maße	155 x 230 mm
Gewicht	422 g
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Anamnese / Körperliche Untersuchung
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
ISBN-10	1-5361-0244-X / 153610244X
ISBN-13	978-1-5361-0244-4 / 9781536102444
Zustand	Neuware