Total Synthesis of (±)-Maoecrystal V

Jianxian Gong (Autor)

Buch | Softcover

XII, 137 Seiten

2016 | Softcover reprint of the original 1st ed. 2014
Springer Berlin (Verlag)
978-3-662-51289-0 (ISBN)

Artikel merken

In this thesis, the author describes the total synthesis of natural product Maoecrystal V in detail. In the first part of the thesis, the author introduces the research background and reviews the research progress in total synthesis of Maoecrystal V. In the second part, the author develops a novel and concise approach for the stereo selective construction of the tetracyclic model system of Maoecrystal V. The model system is accomplished in 8 steps with 20% yield. In the third part, the author describes the first successful total synthesis of Maoecrystal V and investigates four strategies for constructing the key tetrahydrofuran oxa-bridge skeleton. The total synthesis starts from a known compound and is accomplished in 17 steps with 1.2% yield. The successful total synthesis of Maoecrystal V will contribute to the development of efficient synthetic strategies for natural products and other compounds with complex structures.

Research Background for Natural Product Maoecrystal V and Its Family.- The Model Study of Natural Product Maoecrystal V.- The total synthesis study of Maoecrystal V.- Summary.

Erscheinungsdatum	15.09.2016
Reihe/Serie	Springer Theses
Zusatzinfo	XII, 137 p. 177 illus., 1 illus. in color.
Verlagsort	Berlin
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Pharmazie
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Chemie ► Organische Chemie
	Naturwissenschaften ► Chemie ► Physikalische Chemie
Schlagworte	biochemistry • catalysis • Chemistry and Materials Science • Intramolecular Diels-Alder Reaction • Maoecrystal V • medicinal chemistry • natural product • Organic Chemistry • Pinhey Arylation • Stereoselective • Tetrahydrofuran Oxa-Bridge Skeleton • total synthesis • Wessely Oxidative Dearomatization
ISBN-10	3-662-51289-0 / 3662512890
ISBN-13	978-3-662-51289-0 / 9783662512890
Zustand	Neuware