Molecular Testing in Cancer

George M. Yousef, Serge Jothy (Herausgeber)

Buch | Softcover

442 Seiten

2016 | Softcover reprint of the original 1st ed. 2014
Springer-Verlag New York Inc.
978-1-4939-4555-9 (ISBN)

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Molecular Testing in Cancer provides a state of the art review of clinically relevant molecular pathology in cancer. The book provides a brief, easy to read review of commonly employed diagnostic molecular techniques including recently developed "next generation" analytic tools, and offers a system-based run-through of the utility of molecular testing in individual cancer types, as well as reviewing current markers in cancer diagnosis, prognosis, and management. The volume also provides a prospective for the future which includes recently characterized and emerging biomarkers.

Written by experts in the field, Molecular Testing in Cancer serves as a useful and comprehensive resource for pathologists, hematologists, laboratory technicians and molecular scientists.

George M. Yousef, MD, PhD University of Toronto, Department of Laboratory Medicine and Pathobiology, Toronto, ON, Canada Serge Jothy, MD, PhD University of Toronto, Department of Laboratory Medicine and Pathobiology, Toronto, ON, Canada

Transitioning Diagnostic Molecular Pathology to the Genomic Era: Cancer Somatic Mutation Panel Testing.- Conventional and Molecular Cytogenetics in Cancer.- Comparative Genomic Hybridization and Array based CGH in Cancer.- Polymerase Chain Reaction.- Single Nucleotide Polymorphisms (SNPs).- Clinical Application of DNA Sequencing: Sanger and Next-Generation Platforms.- Microarray-based Investigations in Cancer.- Proteomics in Cancer Diagnostics.- Circulating Tumor Cells: A Non-Invasive Liquid Biopsy in Cancer.- Molecular Testing in Hematological Malignancies.- Molecular Testing in Breast Cancer.- Molecular Pathology of Gastrointestinal Tumors.- Molecular Testing in Pulmonary Tumors.- Molecular testing in Gynecological Malignancies.- Molecular Testing in Central Nervous System tumors.- Molecular Testing in Adult Kidney Tumors .- Molecular Testing in Prostate Cancer.- Molecular Testing in Urothelial Tumors.- Molecular Testing in Thyroid Cancer.- Molecular Testing of Head and Neck Tumors.- Molecular Testing in Bone and Soft Tissue Tumors.- Molecular testing in Cutaneous Melanoma.- Molecular Testing in Pediatric Tumors.- Pharmacogenomics in Molecular Oncology.- Quality Assurance in Molecular Testing of Cancer.

Erscheinungsdatum	13.09.2016
Zusatzinfo	84 Illustrations, color; 3 Illustrations, black and white; XI, 442 p. 87 illus., 84 illus. in color.
Verlagsort	New York
Sprache	englisch
Maße	178 x 254 mm
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Hämatologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Laboratoriumsmedizin
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
Schlagworte	epigenetics • methylation analysis • PCR • Proteomics • tumor markers
ISBN-10	1-4939-4555-6 / 1493945556
ISBN-13	978-1-4939-4555-9 / 9781493945559
Zustand	Neuware