Dermatology (eBook)

Robin Graham-Brown, Karen Harman, Graham Johnston (Autoren)

eBook Download: PDF

2016 | 11. Auflage
John Wiley & Sons (Verlag)
978-1-118-88774-5 (ISBN)

Infos

'A very well written introductory dermatology text with excellent clinical photographs and diagrams. We would highly recommend this for those wishing to grasp the basic concepts in dermatology.' British Journal of Dermatology
Dermatology Lecture Notes presents an accessible overview of skin structure and function, along with the practical aspects of disease management. Now in its 11th edition, it has been thoroughly updated to focus on recent advances in the knowledge of skin diseases and their treatment. It combines readability with high quality illustrations, and is the ideal guide for new comers to the specialty as well as those more advanced in their studies.
Key features include:
• An overview of the basics of skin structure and function, as well as practical aspects of disease management
• Excellent clinical photographs, diagrams and histological images
• Newly expanded and updated sections on benign skin tumours, viruses, emergency dermatology (skin failure in particular) and vascular disorders
• Includes a companion website at www.lecturenoteseries.com/dermatology featuring self-assessment and case studies

With beautiful colour artwork throughout, Dermatology Lecture Notes includes a glossary of dermatological terms, and provides an excellent balance between theory and clinical relevance.

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This new edition is also available as an e-book. For more details, please see www.wiley.com/buy/9781118887776 or scan this QR code:

Dermatology Lecture Notes is also available as a digital textbook. For more details, please see http://bit.ly/LNDerm11e

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"e;A very well written introductory dermatology text with excellent clinical photographs and diagrams. We would highly recommend this for those wishing to grasp the basic concepts in dermatology."e; British Journal of Dermatology Dermatology Lecture Notes presents an accessible overview of skin structure and function, along with the practical aspects of disease management. Now in its 11th edition, it has been thoroughly updated to focus on recent advances in the knowledge of skin diseases and their treatment. It combines readability with high quality illustrations, and is the ideal guide for new comers to the specialty as well as those more advanced in their studies. Key features include: An overview of the basics of skin structure and function, as well as practical aspects of disease management Excellent clinical photographs, diagrams and histological images Newly expanded and updated sections on benign skin tumours, viruses, emergency dermatology (skin failure in particular) and vascular disorders Includes a companion website at www.lecturenoteseries.com/dermatology featuring self-assessment and case studies With beautiful colour artwork throughout, Dermatology Lecture Notes includes a glossary of dermatological terms, and provides an excellent balance between theory and clinical relevance.

Inhalt

Title Page 5
Copyright Page 6
Contents 7
Preface 8
Acknowledgements 9
About the companion website 10
Chapter 1 Structure and function of the skin, hair and nails 11
Skin structure 11
The epidermis 11
The dermis 17
Dermatoglyphics 17
Functions of the skin 18
Chapter 2 Approach to the diagnosis of dermatological disease 20
Introduction 20
The value of a diagnosis 20
Dermatological diagnosis 21
The steps to making a dermatological diagnosis 21
Investigation 23
Conclusion 29
Chapter 3 Emergency dermatology 30
Introduction 30
Toxic epidermal necrolysis and Stevens–Johnson syndrome 30
Erythroderma 30
Clinical features 30
Meningococcal septicaemia 31
Necrotizing fasciitis 32
Kaposi’s varicelliform eruption (disseminated herpes simplex/eczema herpeticum) 32
Angioedema (and anaphylaxis) 32
Staphylococcal scalded skin syndrome 33
Final word 33
Chapter 4 Bacterial and viral infections 34
Bacterial infections 34
Streptococcal infection 34
Staphylococcal infection 35
Mycobacterial infection 36
Atypical mycobacteria 38
Viral infections 39
Warts 39
Herpes simplex 42
Herpes zoster (shingles) 43
Chapter 5 Fungal infections 45
Dermatophyte infections 45
Tinea pedis (athlete’s foot) 45
Tinea cruris 46
Tinea corporis 46
Tinea manuum 47
Tinea unguium 47
Tinea capitis 47
Kerion 48
Cattle ringworm 48
Tinea incognito 49
‘Dermatophytide’ reactions 49
Diagnosis 49
Treatment 49
Mycetoma (Madura foot) 51
Candida infection 51
Buccal mucosal candidiasis 51
Angular cheilitis (perlèche) 51
Chronic paronychia 51
Balanoposthitis/vulvovaginitis 52
Intertrigo 52
Pityriasis versicolor 52
Chapter 6 Ectoparasite infections 54
Scabies 54
Aetiology 54
Clinical features 54
Diagnosis 55
Treatment 56
Crusted (Norwegian) scabies 57
Pediculosis 58
Head lice (Pediculus capitis) 58
Clothing lice (Pediculus humanus) 60
Crab lice (Phthirus pubis) 60
Papular urticaria 62
Fleas 62
Bed bugs (Cimex lectularius) 63
Animal mites 63
Ticks 63
Chapter 7 Acne, acneiform eruptions and rosacea 64
Introduction 64
Acne vulgaris and its variants 64
Age of onset and course 64
Psychological impact 65
Clinical features 65
Individual lesions of acne 65
Acne fulminans (acne with systemic symptoms) 67
Pathogenesis 67
Treatment 68
Management 69
Assessment 69
Secondary acne 70
Hidradenitis suppurativa 70
Acneiform disorders 71
Chapter 8 Eczema 73
Clinical features 73
Classification 73
Exogenous eczema 74
Primary irritant contact dermatitis 74
Allergic contact dermatitis 75
Endogenous eczema 78
Atopic dermatitis 78
Seborrhoeic dermatitis 80
Discoid eczema 81
Varicose eczema (stasis dermatitis gravitational eczema)
Endogenous eczema of the palms and soles 81
Asteatotic eczema 81
Juvenile plantar dermatosis 81
Chapter 9 Psoriasis 83
Introduction 83
Pathology 83
Clinical patterns 84
Classic plaque psoriasis 84
Scalp psoriasis 84
Nail psoriasis 85
Guttate psoriasis 86
Flexural psoriasis 86
Unstable or ‘brittle’ psoriasis 86
Erythrodermic psoriasis 87
Acute pustular psoriasis (of von Zumbusch) 87
Chronic palmoplantar pustulosis (pustular psoriasis of palms and soles) 87
Treatment 88
Topical therapies 88
Systemic therapies 90
Treatment of clinical patterns of psoriasis 90
Chronic plaque psoriasis 91
Scalp psoriasis 91
Nail psoriasis 91
Guttate psoriasis 91
Flexural psoriasis 91
Unstable or ‘brittle’ psoriasis 91
Erythrodermic and acute pustular psoriasis 91
Chronic palmoplantar pustulosis 91
Arthropathic psoriasis 91
Reiter’s syndrome 92
Chapter 10 Benign and malignant skin tumours 93
Classification of skin tumours 93
General treatment principles for skin tumours 93
Surgical removal or biopsy 93
Curettage and/or cautery 94
Cryotherapy 94
Radiotherapy 95
Lasers and photodynamic therapy 95
Specific tumours 95
Benign epidermal tumours 95
Epidermal cysts 97
Benign melanocytic tumours 97
Benign dermal tumours 97
Pseudo-tumours 99
Dysplastic and malignant tumours 100
Dysplastic/malignant epidermal tumours 100
Dysplastic/malignant melanocytic tumours 104
Prevention of epidermal and melanocytic malignancies 107
Malignant dermal tumours 107
Extension from deeper tissues and metastases 108
Chapter 11 Naevi 109
Introduction 109
Naevi arising from cutaneous epthelium and ‘organoid’ naevi 109
Epidermal naevus 109
Sebaceous naevus 109
Melanocytic naevi 110
Congenital 110
Acquired 111
Vascular naevi 113
Vascular malformations 113
Infantile haemangiomas 114
Other naevi 115
Chapter 12 Inherited disorders 116
The ichthyoses 116
Ichthyosis vulgaris (autosomal dominant ichthyosis) 116
X-linked recessive ichthyosis 116
Ichthyosiform erythroderma and lamellar ichthyosis 116
Epidermolytic hyperkeratosis 117
Genetic disorders of which ichthyosis is a component 117
Acquired ichthyosis 117
Treatment 117
Collodion baby 117
Palmoplantar keratoderma 118
Darier’s disease (keratosis follicularis) 118
Epidermolysis bullosa 119
Ehlers–Danlos syndrome 119
Tuberous sclerosis complex 119
Neurofibromatosis 119
Peutz–Jeghers syndrome 121
Hereditary haemorrhagic telangiectasia (Osler–Weber–Rendu disease) 121
Basal cell naevus syndrome (Gorlin’s syndrome) 121
Gardner’s syndrome 121
Ectodermal dysplasias 121
Pseudoxanthoma elasticum 121
Xeroderma pigmentosum 122
Acrodermatitis enteropathica 122
Angiokeratoma corporis diffusum (Anderson–Fabry disease) 122
Incontinentia pigmenti 123
Chromosomal abnormalities 123
Chapter 13 Pigmentary disorders 124
Introduction: normal pigmentary mechanisms 124
Hypo- and depigmentation 125
Congenital 125
Acquired 125
Hyperpigmentation 127
Congenital 127
Acquired 127
Chapter 14 Disorders of the hair and nails 129
Introduction 129
Hair abnormalities 129
Changes in the physical properties of scalp hair 129
Scalp hair loss 130
Excessive hair and hair in abnormal sites 133
Nail abnormalities 133
Common disorders of the paronychium 136
Chapter 15 Bullous disorders 137
Causes 137
Physical causes of bullae 138
Oedema 138
Arthropods 138
Drugs 138
Skin disorders 138
Linear IgA disease 144
Rarer blistering diseases 145
Porphyria cutanea tarda 145
Toxic epidermal necrolysis 145
Bullous erythema multiforme (Stevens–Johnson syndrome) 146
Chapter 16 Miscellaneous erythematous and papulosquamous disorders, and light-induced skin diseases 147
Urticaria and angioedema 147
Clinical features 147
Clinical forms of urticaria and angioedema 148
Treatment of urticaria 149
Erythema multiforme 149
History 149
Aetiology 150
Examination 150
Treatment 150
Stevens–Johnson syndrome 150
Erythroderma (exfoliative dermatitis) 151
Erythema nodosum 151
Lichen planus 152
Sites of predilection 152
Clinical features 152
Aetiology 152
Treatment 153
Lichen sclerosus 153
Sites of predilection 153
Clinical features 153
Complications 153
Childhood disease 154
Disease in males 154
Treatment 154
Pityriasis rosea 154
Clinical features 154
Treatment 154
Atypical pityriasis rosea 154
Pityriasis lichenoides 155
Pityriasis rubra pilaris 155
Miliaria or ‘prickly heat’ 155
Pregnancy rashes 155
Light-induced skin disease 156
Sunburn 156
Polymorphic light eruption 157
Actinic prurigo 157
Juvenile spring eruption 157
Photosensitive eczema and chronic actinic dermatitis 157
Porphyrias 157
Pellagra 158
Xeroderma pigmentosum 158
Phytophotodermatitis 158
Light-induced drug reactions 158
Disorders exacerbated by light 158
Chapter 17 Vascular disorders 159
Leg ulcers 159
Venous leg ulcers 159
Ischaemic ulcers 162
Vasculitic ulcers 162
Neoplastic ulcers 162
Haematological disorders and leg ulcers 162
Vasculitis 162
Small vessels 163
Larger vessels 164
Other disorders involving blood vessels 165
Behçet’s disease 165
Pyoderma gangrenosum 165
Perniosis (chilblains) 165
Chapter 18 Connective tissue diseases 166
Lupus erythematosus 166
Discoid lupus erythematosus 166
Systemic lupus erythematosus 167
Subacute cutaneous lupus erythematosus 168
Antiphospholipid syndrome 168
Neonatal lupus erythematosus 168
Drug-induced systemic lupus erythematosus 168
Dermatomyositis 168
Skin 168
Muscles 169
Investigations 169
Treatment 170
Scleroderma 170
Morphoea 170
Systemic sclerosis and CREST syndrome 171
Chemically induced scleroderma 173
Pseudoscleroderma 173
Nephrogenic systemic fibrosis 173
Chapter 19 Pruritus 174
Mechanisms of pruritus 174
Causes of pruritus 175
Localized pruritus 175
Generalized pruritus 176
‘Senile’ pruritus 178
Chapter 20 Systemic disease and the skin 179
Endocrine disease 179
Diabetes 179
Granuloma annulare 180
Thyroid disease 181
Hypothyroidism 181
Hyperthyroidism 181
Adrenal disease 182
Cushing’s syndrome 182
Addison’s disease 182
Rheumatic diseases 182
Gout 182
Still’s disease 182
Rheumatoid arthritis 182
Rheumatic fever 182
Reiter’s disease (reactive arthritis) 182
Vitamin deficiency 182
Scurvy 182
Pellagra 182
Inflammatory bowel disease 182
Hyperlipidaemia 183
Amyloidosis 184
Sarcoidosis 184
Liver disease and the skin 185
Cutaneous manifestations of systemic malignancy 185
Cutaneous metastases 185
Miscellaneous cutaneous signs of underlying malignancy 185
Leukaemia and the skin 186
Purpura 186
AIDS and the skin 186
Chapter 21 Skin and the psyche 188
Dermatitis artefacta 188
Dermatological pathomimicry 190
Body dysmorphic disorder (dermatological non-disease dysmorphophobia)
Delusions of parasitosis 190
Obsessive–compulsive habits 191
Trichotillomania 191
Pathological skin-picking 192
Compulsive handwashing 192
Chapter 22 Cutaneous drug reactions 193
Introduction 193
Drug reaction patterns 193
Exanthematic eruptions 194
Urticaria and anaphylaxis 194
Eczema 194
Erythroderma 195
Vasculitis 195
Fixed drug eruptions 195
Lichen planus-like eruptions 195
Erythema multiforme 195
Stevens–Johnson syndrome and toxic epidermal necrolysis 196
Drug reaction with eosinophilia and systemic symptoms 196
Acute generalized exanthematic pustulosis 196
Acneiform eruptions 196
Hair abnormalities 196
Pigmentary changes 197
Bullous reactions 197
Photosensitivity 197
Lupus erythematosus-like syndrome 198
Exacerbation of pre-existing disease 198
Conclusion 198
Chapter 23 Treatment of skin disease 199
Topical therapy 199
Bases 199
Communication and patient compliance (adherence) 200
Quantities prescribed 200
Topical steroids 201
Choice of preparation 201
Side effects 201
Topical immunomodulators 203
Vitamin D analogues 203
Retinoids 204
Topical therapies directed at dysplasia and skin cancers 204
Phototherapy and photochemotherapy (PUVA) 204
UVB 204
PUVA 204
Systemic therapy 205
Retinoids 205
Methotrexate 206
Azathioprine 206
Ciclosporin 206
Biologic interventions 206
Glossary of dermatological terms 207
Index 212
EULA 223

Produkt-Details

• Erscheint lt. Verlag: 18.5.2016
• Reihe/Serie: Lecture Notes
• Reihe/Serie: Lecture Notes
• Reihe/Serie: Lecture Notes
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Dermatologie
• Themenwelt: Medizin / Pharmazie ► Studium
• Schlagworte: bacterial • Dermatological • Dermatologie • Dermatology • Disease • eczema • Fungal • Hair • Infection • medical education • Medical Science • Medizin • Medizinstudium • Psoriasis • Skin • Tumours • Viral
• ISBN-10: 1-118-88774-3 / 1118887743
• ISBN-13: 978-1-118-88774-5 / 9781118887745