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Alcohol Abuse and Liver Disease (eBook)

James Neuberger (Herausgeber)

(Autor)

eBook Download: EPUB
2016
John Wiley & Sons (Verlag)
9781118887295 (ISBN)

Lese- und Medienproben

Alcohol Abuse and Liver Disease - Andrea DiMartini
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For people with alcohol excess and liver disease, successful management must be two-fold with management of both their psychological/physical addiction to alcohol and their liver disease. Alcohol Abuse and liver disease, with its joint focus on hepatology and psychiatry, provides both hepatologists and psychiatrists of all levels with a practical, concise and didactic guide to the investigation and clinical management of those with alcohol-related problems. Edited by a practicing hepatologist in the UK and a practising specialist in psychiatry/substance abuse in the US, it covers areas such as: Risk factors for alcoholic liver disease Interaction of alcohol with other co-morbidities Clinical assessment of alcohol intake Detoxification and management of withdrawal Psychotherapeutic and pharmaceutical interventions Treatment of liver disease Key points, management diagrams and high-quality images are all be supported by the very latest in clinical guidelines from the major hepatology and psychiatry societies such as the APA, EPA, AASLD and EASL. With increasing emphasis on multi-disciplinary speciality care in this area, this is the ideal tool to consult in order to provide the best care possible care for what are very challenging patients to manage.

James Neuberger MD, is a Consultant Hepatologist and Professor of Hepatology, Queen Elizabeth Hospital, Birmingham and Associate Medical Director at NHS Blood and Transplant. He is Editor-in-Chief of LWW's Transplantation, the journal of the Transplantation Society, and on the board of several liver and transplant journals. He has 295 articles listed on PubMed. Andrea DiMartini is Associate Professor of Psychiatry and Surgery in the Department of Psychiatry in the University of Pittsburgh. She has over 20 years' clinical and research experience of working with transplant surgeons and physicians in the Starzl Transplantation Institute. She was awarded the 2011 Research Award by the Academy of Psychosomatic Medicine and has focused on the natural history and management of patients with alcohol and substance abuse.

List of Contributors vii

Preface xi

1 Epidemiology of alcohol use 1
Ian Gilmore and William Gilmore

2 Epidemiology of alcohol?]related liver disease 11
Ed Britton and Martin Lombard

3 Alcoholism: diagnosis and natural history in the context of medical disease 23
Thomas P. Beresford Narin Wongngamnit and Benjamin A. Temple

4 Alcohol and other substance misuse 35
John B. Saunders

5 Risk factors for alcohol?]related liver disease 47
Stuart Kendrick and Chris Day

6 Mechanisms of alcohol toxicity 55
Guruprasad P. Aithal and Jane I. Grove

7 Extrahepatic manifestations of alcohol excess 65
Karl?]Heinz Schulz Sandra van Eckert and Jens Reimer

8 Patterns of alcohol?]associated liver damage 79
Peter Hayes and Michael Williams

9 Cofactors and alcohol?]related liver disease 87
John G. O'Grady

10 Impact of alcohol and liver disease on prescribing 91
Richard Parker and Amanda Smith

11 Psychiatric examination of liver transplant patients with alcohol use disorders 99
Robert M. Weinrieb and Omair Abbasi

12 Abnormal liver tests in the context of alcohol excess 109
James Ferguson

13 Biochemical determination of alcohol consumption 113
Friedrich Martin Wurst Natasha Thon Wolfgang Weinmann Michel Yegles Jessica Wong and Ulrich W. Preuss

14 The role of histology 123
Desley A.H. Neil

15 General assessment and management 135
Patrizia Burra and Giacomo Germani

16 Brief alcohol interventions 147
Stephanie Scott and Eileen Kaner

17 Alcohol withdrawal syndrome: diagnosis and treatment 155
Julie Taub and Thomas P. Beresford

18 Psychosocial treatments of alcohol use disorders 165
Terry D. Schneekloth

19 Pharmacologic interventions 175
Renata Yang and Marian Fireman

20 Treatment of extrahepatic manifestations of alcohol abuse 187
Joaquim Fernandez?]Sola

21 Treatment of liver disease 197
James Neuberger

22 Treatment of alcoholic hepatitis 203
Mark Thursz and Stephen Atkinson

23 Liver transplantation in people with alcohol?]related liver disease 215
Santiago Tome and Michael R. Lucey

24 Future directions: the need for early identification and intervention for patients with excessive alcohol use 223
Andrea DiMartini Shari Rogal and Stephen Potts

Index 235

List of Contributors


Omair Abbasi MD
Assistant Professor, Department of Psychiatry and Human Behavior
Thomas Jefferson University Hospitals
Sidney Kimmel School of Medicine
Philadelphia, PA, USA

Guruprasad P. Aithal BSc, MBBS, MD, FRCP, PhD
Professor of Hepatology, Director, National Institute for Health Research (NIHR) Nottingham Digestive Diseases
Biomedical Research Unit
Nottingham University Hospitals NHS Trust and the University of Nottingham
Nottingham, UK

Stephen Atkinson MBBS, MA, MRCP
Clinical Research Fellow, Gastroenterology and Hepatology
Department of Medicine, Imperial College London
London, UK

Thomas P. Beresford MD
Professor of Psychiatry
University of Colorado School of Medicine;
Physician, Laboratory for Clinical and Translational Research in Psychiatry
Department of Veterans Affairs Medical Center
Denver, CO, USA

Ed Britton MBBS, MRCP
Fellow in Hepatology
Royal Liverpool University Hospital
Liverpool, UK

Patrizia Burra MD
Head, Multivisceral Transplant Unit
Department of Surgery
Oncology and Gastroenterology
Padova University Hospital
Padova, Italy

Chris Day MA, MBBChir, MD PhD, FRCP
Pro-Vice-Chancellor, Faculty of Medical Sciences;
Consultant Physician, Institute of Cellular Medicine
Newcastle University
Newcastle upon Tyne, UK

James Ferguson MD, FRCPE
Consultant Hepatologist, Liver Unit
Queen Elizabeth Hospital Birmingham
Birmingham;
Associate Medical Director
Organ Donation and Transplantation
NHS Blood and Transplant
Bristol, UK

Joaquim Fernández-Solà MD, PhD
Medical Senior Consultant in Internal Medicine
Alcohol Unit, Hospital Clínic, Institut
d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)
CIBEROBN Fisiopatología de la Obesidad y la Nutrición, Instituto de Salud Carlos III;
Professor of Medicine, University of Barcelona
Barcelona, Spain

Marian Fireman MD
Associate Professor of Psychiatry
Oregon Health and Science University
Portland, OR, USA

Giacomo Germani MD, PhD, FEBTM
Consultant Physician, Multivisceral Transplant Unit
Department of Surgery
Oncology and Gastroenterology
Padova University Hospital
Padova, Italy

Ian Gilmore MD, FRCP
Honorary Professor
Department of Medicine
University of Liverpool
Liverpool, UK;
Adjunct Professor
National Drug Research Institute, Faculty of Health Sciences
Curtin University
Perth, Australia

William Gilmore BSc, MSc
Research Fellow
National Drug Research Institute
Faculty of Health Sciences
Curtin University
Perth, Australia

Jane I. Grove BSc, PhD
Postdoctoral Research Fellow
National Institute for Health Research (NIHR)
Nottingham Digestive Diseases Biomedical Research Unit
Nottingham University Hospitals NHS Trust and the University of Nottingham
Nottingham, UK

Peter Hayes PhD, FRCP(Ed)
Professor of Hepatology
Department of Gastroenterology
Royal Infirmary of Edinburgh
Edinburgh, UK

Eileen Kaner PhD
Professor of Public Health Research
Institute of Health and Society
Newcastle University
Newcastle upon Tyne, UK

Stuart Kendrick MA, BMBCh, PhD, MRCP
Consultant Physician
Institute of Cellular Medicine
Newcastle University
Newcastle upon Tyne, UK

Martin Lombard MB, BCh, BAO, MD, MSc, FRCPI, FRCP
Professor and Consultant Hepatologist and Gastroenterologist
Gastroenterology and Liver Services
Royal Liverpool University Hospital
Liverpool, UK

Michael R. Lucey MD
Professor and Chief of Division
Department of MedicineDivision of Gastroenterology and Hepatology
University of Wisconsin School of Medicine and Public Health
Madison, WI, USA

Andrea DiMartini MD
Associate Professor of Psychiatry
Associate Professor of Surgery
Medical Director, Psychosomatic Medicine Transplant Program
Starzl Transplant Institute
University of Pittsburgh Medical Center
Pittsburgh, PA, USA

Desley A.H. Neil FRCPath, MBBS, PhD, BMedSc
Consultant Histopathologist
Queen Elizabeth Hospital Birmingham
Birmingham, UK

James Neuberger DM, FRCP
Honorary Consultant
Liver Unit
Queen Elizabeth Hospital Birmingham
Birmingham;
Associate Medical Director
Organ Donation and Transplantation
NHS Blood and Transplant
Bristol, UK

John G. O’Grady MD, FRCPI
Professor of Hepatology
Institute of Liver Studies
King’s College Hospital
London, UK

Richard Parker MBChB, MRCP
MRC Clinical Research Training Fellow
NIHR Centre for Liver Research and Biomedical Research Unit
University of Birmingham;
Honorary Hepatology Registrar
University Hospitals Birmingham NHS Foundation Trust
Birmingham, UK

Stephen Potts MA FRCPsych FRCPE
Consultant in Transplant Psychiatry
Department of Psychological Medicine
Royal Infirmary of Edinburgh;
Honorary Senior Clinical Lecturer
University of Edinburgh
Edinburgh, UK

Ulrich W. Preuss MD
Professor of Psychiatry
Kreiskrankenhaus Prignitz, Perleberg;
Department of Psychiatry, Psychotherapy and Psychosomatic Medicine
University of Halle
Halle, Germany

Jens Reimer MD, MBA
Professor
Department of Psychiatry and Psychotherapy
Center for Interdisciplinary Addiction Research
University Medical Center Hamburg-Eppendorf (UKE)
Hamburg, Germany

Shari Rogal MD, MPH
Gastroenterologist and Transplant Hepatologist
VA Pittsburgh Healthcare System;
Center for Health Equity Research and Promotion
VA Pittsburgh Healthcare System;
Visiting Assistant Professor of Surgery
Division of Gastroenterology
Hepatology and Nutrition University of Pittsburgh
Pittsbugh, PA, USA

John B. Saunders MA, MB, BChir, MD, FRACP, FAChAM, FRCP
Professor, Faculty of Medicine and Biomedical Sciences
University of Queensland
Queensland;
Disciplines of Psychiatry and Addiction Medicine
Sydney Medical School, University of Sydney
New South Wales, Australia

Terry D. Schneekloth MD
Assistant Professor of Psychiatry
Mayo Clinic
Rochester, MN, USA

Karl-Heinz Schulz MD, PhD
Professor
Institute of Medical Psychology and Center for Transplantation Medicine
University Medical Center Hamburg-Eppendorf (UKE)
Hamburg, Germany

Stephanie Scott PhD
Research Associate
Human Nutrition Research Centre and Institute of Health and Society
Newcastle University
Newcastle upon Tyne, UK

Amanda Smith BPharm(hons), MRPharmS, DipClinPharm
Lead Pharmacist, Liver and Solid Organ
Transplantation
University Hospitals Birmingham NHS Foundation Trust
Birmingham, UK

Julie Taub MD
Assistant Professor of Medicine
University of Colorado School of Medicine;
Hospitalist, Department of Medicine
Denver Health Medical Center
Denver, CO, USA

Benjamin A. Temple
Professional Research Assistant
University of Colorado School of Medicine;
Laboratory for Clinical and Translational Research in Psychiatry
Department of Veterans Affairs Medical Center
Denver, CO, USA

Natasha Thon MSc
Department for Psychiatry and Psychotherapy II
Christian-Doppler Hospital
Paracelsus Medical University
Salzburg, Austria

Mark Thursz MD, FRCP
Professor of Hepatology
Department of Medicine, Imperial College London
London, UK

Santiago Tomé MD
Professor
Hepatology Unit, Internal Medicine Department
Hospital Universitario de Santiago de Compostela
Santiago de Compostela, Spain

Sandra van Eckert RN, MCommH, MPH, PhD
Research Associate
Institute of Medical Psychology and Center for Transplantation Medicine
University Medical Center Hamburg-Eppendorf (UKE)
Hamburg, Germany

Wolfgang Weinmann PhD
Professor
Institute of Forensic Medicine
University of Berne
Berne, Switzerland

Robert M. Weinrieb MD, FAPM
Director, Psychosomatic Medicine and Psychosomatic Medicine Fellowship
Department of Psychiatry
University of Pennsylvania Health System
Perelman School of Medicine
Philadelphia, PA, USA

Michael Williams BMBCh, PhD, MRCP
Specialist Registrar
Department of Gastroenterology
Royal Infirmary of Edinburgh
Edinburgh, UK

Jessica Wong MD
Kreiskrankenhaus Prignitz
Perleberg, Germany

Narin Wongngamnit MD
Addiction Psychiatrist, Substance Abuse Treatment Program
Department of Veterans Affairs;
Instructor in Psychiatry, School of...

Erscheint lt. Verlag 21.3.2016
Sprache englisch
Themenwelt Medizin / Pharmazie Allgemeines / Lexika
Medizinische Fachgebiete Innere Medizin Gastroenterologie
Medizinische Fachgebiete Innere Medizin Hepatologie
Medizin / Pharmazie Medizinische Fachgebiete Suchtkrankheiten
Schlagworte Addictions • Alcoholism, liver failure, hepatology, substance abuse, alcohol, cirrhosis, alcohol abuse, liver disease, alcoholic liver disease • Gastroenterologie u. Hepatologie • Gastroenterology & Hepatology • Medical Science • Medizin • Psychologie • Psychology • Substance Misuse • Substanzmissbrauch • Sucht
ISBN-13 9781118887295 / 9781118887295
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