Cirrhosis (eBook)
John Wiley & Sons (Verlag)
978-1-118-41267-1 (ISBN)
Cirrhosis: a practical guide to management providesgastroenterologists and hepatologists with an up-to-date clinicalguide presenting the very best evidence-based practice in thediagnosis, treatment and management of liver cirrhosis and its manycomplications. Designed to offer practical guidance at alltimes, it provides doctors with an extremely useful tool in theclinical setting, with each chapter featuring diagnostic/managementalgorithms, key points and other pedagogic features.
Divided into 2 parts, a diagnosis and pathophysiology section and amanagement of complications section, key topics include:
- Diagnostic laboratory tests
- Diagnostic imaging modalities
- Acute-on chronic liver failure
- Agents and drugs to avoid
- End stage liver failure: liver transplant evaluation
- Hepatocellular carcinoma
Aimed at the specialist, as well as the practicing trainee at thetop-end of specialty training, the emphasis throughout is onproviding optimum clinical management guidance most relevant topracticing hepatologists and gastroenterologists, and is aninvaluable guide to this increasingly common condition.
Samuel S. Lee, MD, Professor, Department of Medicine and Head,Division of Gastroenterology, University of Calgary, Canada. SamLee is one of the world’s leading lights on cirrhosis and iseditor-in-chief of the Wiley journal Liver International,the official journal of the International Association for the Study of theLiver.
Richard Moreau, MD, Head and Director of Research at theNational Institute of Health (Inserm), Paris, France.
Cirrhosis: a practical guide to management provides gastroenterologists and hepatologists with an up-to-date clinical guide presenting the very best evidence-based practice in the diagnosis, treatment and management of liver cirrhosis and its many complications. Designed to offer practical guidance at all times, it provides doctors with an extremely useful tool in the clinical setting, with each chapter featuring diagnostic/management algorithms, key points and other pedagogic features. Divided into 2 parts, a diagnosis and pathophysiology section and a management of complications section, key topics include: - Diagnostic laboratory tests - Diagnostic imaging modalities - Acute-on chronic liver failure - Agents and drugs to avoid - End stage liver failure: liver transplant evaluation - Hepatocellular carcinoma Aimed at the specialist, as well as the practicing trainee at the top-end of specialty training, the emphasis throughout is on providing optimum clinical management guidance most relevant to practicing hepatologists and gastroenterologists, and is an invaluable guide to this increasingly common condition.
Samuel S. Lee, MD, Professor, Department of Medicine and Head, Division of Gastroenterology, University of Calgary, Canada. Sam Lee is one of the world's leading lights on cirrhosis and is editor-in-chief of the Wiley journal Liver International, the official journal of the International Association for the Study of the Liver. Richard Moreau, MD, Head and Director of Research at the National Institute of Health (Inserm), Paris, France.
List of contributors vii
Foreword xi
List of abbreviations xiii
Part 1: Diagnosis and pathophysiology
1 Clinical clues to the diagnosis of cirrhosis 3
Y.K. Chawla and Vijay Bodh
2 Diagnostic laboratory tests 12
Ying-Ying Yang and Han-Chieh Lin
3 Diagnostic imaging modalities 21
Soon Koo Baik Moon Young Kim and Woo Kyoung Jeong
4 Histology/pathology 35
Valérie Paradis
5 Fibrosis and fibrogenesis 46
Namiki Izumi Nobuharu Tamaki Yasuhiro Asahina and Masayuki Kurosaki
6 Non-invasive diagnosis tests 53
Laurent Castera
7 Evaluating prognosis 63
Sumeet K. Asrani and Patrick S. Kamath
8 End-stage liver failure: liver transplant evaluation 75
Sebastián Marciano and Adrián Gadano
Part 2: Complications of cirrhosis
9 Acute-on-chronic liver failure 87
Danielle Adebayo Vincenzo Morabito and Rajiv Jalan
10 Hepatocellular carcinoma 94
Kwang-Hyub Han and Do Young Kim
11 Hepatic encephalopathy 105
Piero Amodio
12 Malnutrition and nutritional support 124
Jian-Gao Fan and Hai-Xia Cao
13 Varices portal hypertensive gastropathy and GAVE 137
Isabelle Colle Xavier Verhelst Anja Geerts and Hans Van Vlierberghe
14 Ascites 151
Andrés Cárdenas Isabel Graupera and Pere Ginès
15 Spontaneous bacterial peritonitis and other infections 164
Thierry Gustot and Richard Moreau
16 Hepatorenal syndrome and acute kidney injury 175
Florence Wong
17 The hepatopulmonary syndrome 189
Moises Ilan Nevah Rubin and Michael B. Fallon
18 Hyponatremia and other electrolyte/ion disorders 199
Salvatore Piano Filippo Morando and Paolo Angeli
19 Portopulmonary hypertension 212
Rodrigo Cartin-Ceba and Michael J. Krowka
20 Cirrhotic cardiomyopathy 225
Hongqun Liu and Samuel S. Lee
21 Adrenal insufficiency 236
Emily Dannhorn and James O'Beirne
22 Coagulopathy and clotting disorders 249
Marco Senzolo and A.K. Burroughs
23 Agents and drugs: precautions in patients with cirrhosis 261
Felix Stickel
24 Changing outcomes with antiviral or antifibrotic therapies 274
Gamal Esmat and Maissa El Raziky
25 Bone disorders 283
Jane Collier
26 Pruritus 291
Nora V. Bergasa
27 Quality of life and symptom management 301
Ayman A. Abdo and Faisal M. Sanai
28 Special considerations in children 311
Alejandro Costaguta and Fernando Alvarez
Index 323
List of Contributors
Ayman A. Abdo, MD, FRCPC
Professor, Division of Gastroenterology, Department of Medicine, College of Medicine, King Saud University;
King Saud University Liver Disease Research Center, Riyadh, Saudi Arabia
Danielle Adebayo, BSc, MBBS, MRCP
Hepatology Research Fellow, Liver Failure Group, UCL Institute for Liver and Digestive Health,
UCL Medical School, Royal Free Hospital, London, UK
Fernando Alvarez, MD
Professor of Pediatrics, Department of Pediatrics, CHU- Sainte Justine, University of Montreal, Quebec, Canada
Piero Amodio, MD
Professor of Internal Medicine, Department of Medicine (DIMED), University of Padova, Padova, Italy
Paolo Angeli, MD, PhD
Professor of Medicine, Department of Medicine (DIMED), Unit of Hepatic Emergencies and Liver Transplantation, University of Padova, Padova, Italy
Yasuhiro Asahina, MD, PhD
Professor, Department of Hepatitis Investigation, Tokyo Medical and Dental University, Tokyo, Japan
Sumeet K. Asrani, MD, MSc
Hepatology Fellow, Baylor University Medical Center, Dallas, Texas, USA
Soon Koo Baik, MD, PhD
Professor of Internal Medicine, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea
Nora V. Bergasa, MD
Chief, Department of Medicine, Metropolitan Hospital Center, New York, NY, USA;
Professor of Medicine, New York Medical College, Valhalla, New York, NY, USA
Vijay Bodh, MD
Fellow in DM (Heptology), Department of Hepatology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
A.K. Burroughs, MD (deceased)
The Royal Free Sheila Sherlock Liver Centre and University Department of Surgery, Department of Intensive Care, Royal Free Hospital, London, UK
Hai-Xia Cao, PhD, MD
Department of Gastroenterology, Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition,
Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China
Andrés Cárdenas, MD, MMSc, AGAF
Faculty Member, Senior Specialist, GI Unit, Hospital Clínic and University of Barcelona, Institut d'Investigacions Biomèdiques August Pi-Sunyer (IDIBAPS), Ciber de Enfermedades Hepaticas y Digestivas (CIBERHED)
Rodrigo Cartin-Ceba, MD
Assistant Professor of Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA
Laurent Castera, MD, PhD
Senior Consultant in Hepatology, Department of Hepatology, Hopital Beaujon, Assistance Publique-Hôpitaux de Paris, INSERM U773, Clichy, France
Y.K. Chawla, MD, DM (Gastroenterology), FAMS
Professor, Department of Hepatology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
Isabelle Colle, MD, PhD
Full Professor, Ghent University, Belgium;
Department of Hepatology and Gastroenterology, Algemeen Stedelijk Ziekenhuis (ASZ), Aalst, Belgium and Ghent University
Jane Collier, MD, MBChB, FRCP
Consultant in Hepatology, John Radcliffe Hospital, Oxford, UK
Alejandro Costaguta, MD
Jefe, Servicio de Gastroenterología, Hepatología y Nutrición, Sanatorio de Niños, Rosario, Santa Fe, Argentina
Emily Dannhorn, MBBS, MRCP
Specialist Registrar in Hepatology, Sheila Sherlock Liver Centre, Royal Free Hospital, London, UK
Maissa El Raziky, MD
Professor of Endemic Medicine and Hepatology, Director of the Hepatic Schistosomiasis Research Unit, Faculty of Medicine, Cairo University, Cairo, Egypt
Gamal Esmat, MD
Vice President for Graduate Studies and Research Cairo University, Professor of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Cairo, Egypt
Michael B. Fallon, MD
Professor of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, The University of Texas, Health Science Center at Houston, Houston, TX, USA
Jian-Gao Fan, PhD, MD
Professor and Director, Department of Gastroenterology, Shanghai Key Laboratory of Pediatric, Gastroenterology and Nutrition, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China
Adrián Gadano, MD, PhD
Associate Professor and Chief, Department of Medicine and Liver Unit, Hospital Italiano, Buenos Aires, Argentina
Anja Geerts, MD, PhD
Professor, Ghent University, Belgium;
Department of Hepatology and Gastroenterology, Ghent University Hospital, Ghent, Belgium
Pere Ginès, MD, PhD
Chairman – Liver Unit, Professor of Medicine, Liver Unit, Hospital Clínic and University of Barcelona; Institut d'Investigacions Biomèdiques August Pi-Sunyer (IDIBAPS);
Ciber de Enfermedades Hepaticas y Digestivas (CIBERHED);
Instituto Reina Sofía de Investigación Nefrológica (IRSIN), Barcelona, Spain
Isabel Graupera, MD
Liver Unit, Hospital Clínic and University of Barcelona;
Institut d'Investigacions Biomèdiques August Pi-Sunyer (IDIBAPS), Ciber de Enfermedades Hepaticas y Digestivas (CIBERHED), Instituto Reina Sofía de Investigación Nefrológica (IRSIN), Barcelona, Spain
Thierry Gustot, MD, PhD
Associate Professor, Department of Gastroenterology and Hepato-Pancreatology, Erasme Hospital, Brussels, Belgium
Laboratory of Experimental Gastroenterology, Université Libre de Bruxelles, Brussels, Belgium;
INSERM, U773, Centre de Recherche Biomédicale Bichat-Beaujon CRB3, Paris, France
Kwang-Hyub Han, MD
Professor and Chairman, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
Namiki Izumi, MD, PhD
Chief, Vice President, Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
Rajiv Jalan, MBBS, MD, PhD, FRCPE, FRCP
Professor of Hepatology, Liver Failure Group, UCL Institute for Liver and Digestive Health, UCL Medical School, Royal Free Hospital, London, UK
Woo Kyoung Jeong, MD, PhD
Assistant Professor of Radiology, Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
Patrick S. Kamath, MD
Professor of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN, USA
Do Young Kim, MD, PhD
Associate Professor, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
Moon Young Kim, MD, PhD
Associate Professor of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea
Michael J. Krowka, MD
Professor of Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA
Masayuki Kurosaki, MD, PhD
Director, Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
Samuel S. Lee, MD, FRCPC
Professor of Medicine, University of Calgary Cumming School of Medicine, Calgary, Canada
Han-Chieh Lin, MD, FAGG
Professor and Chief, Department of Gastroenterology and Hepatology, Taipei Veterans General Hospital and National Yang-Ming University School of Medicine, Taipei, Taiwan
Hongqun Liu, MD, PhD
Research Assistant Professor, University of Calgary Cumming School of Medicine, Calgary, Canada
Sebastián Marciano, MD
Assistant Professor, Liver Unit, Hospital Italiano, Buenos Aires, Argentina
Vincenzo Morabito, MBBS
Clinical Research Fellow, Liver Failure Group, UCL Institute for Liver and Digestive Health, UCL Medical School Royal Free Hospital, London, UK
Filippo Morando, MD
Hepatology Fellow, Department of Medicine (DIMED), University of Padova, Padova, Italy
Richard Moreau, MD
INSERM, U1149, Centre de Recherche sur l'Inflammation (CRI);
UMR S 1149, Université Paris Diderot-Paris 7, Faculté de Médecine Bichat;
Département Hospitalo-Universitaire (DHU) UNITY, Service d'Hépatologie, Hôpital Beaujon, Assistance Publique-Hôpitaux de Paris, Clichy, France
James O'Beirne, MBBS (Hons), MD, FRCP, EDIC
Consultant Hepatologist, Sheila Sherlock Liver Centre, Royal Free Hospital, London, UK
Valérie Paradis, MD, PhD
Professor, Pathology Department, Beaujon Hospital, INSERM URM 1149, Paris, France
Salvatore Piano, MD
Hepatology Fellow, Department of Medicine (DIMED), University of Padova, Padova, Italy
Moises Ilan Nevah Rubin, MD
Assistant Professor of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA
Faisal M. Sanai, MD, ABIM, SBG
Consultant Transplant Hepatologist, Department of Hepatobiliary Science and Liver Transplantation, King Abdul Aziz Medical City;
King Saud University Liver Disease Research Center, Riyadh, Saudi Arabia
Marco Senzolo, MD
Multivisceral Transplant Unit, Gastroenterology, Department of...
| Erscheint lt. Verlag | 22.1.2015 |
|---|---|
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Allgemeines / Lexika |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Chirurgie | |
| Medizinische Fachgebiete ► Innere Medizin ► Gastroenterologie | |
| Medizinische Fachgebiete ► Innere Medizin ► Hepatologie | |
| Schlagworte | addiction • Alcohol • alcoholic liver disease • Cirrhosis • Gastrointestinal surgery • Gesundheits- u. Sozialwesen • Health & Social Care • Hepatologie • hepatologist • hepatology • Leberzirrhose • Liver • liver disease • Liver failure • Magen-Darm-Chirurgie • Medical Science • Medizin • Suchtforschung • Zirrhose |
| ISBN-10 | 1-118-41267-2 / 1118412672 |
| ISBN-13 | 978-1-118-41267-1 / 9781118412671 |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
| Haben Sie eine Frage zum Produkt? |
Kopierschutz: Adobe-DRM
Adobe-DRM ist ein Kopierschutz, der das eBook vor Mißbrauch schützen soll. Dabei wird das eBook bereits beim Download auf Ihre persönliche Adobe-ID autorisiert. Lesen können Sie das eBook dann nur auf den Geräten, welche ebenfalls auf Ihre Adobe-ID registriert sind.
Details zum Adobe-DRM
Dateiformat: EPUB (Electronic Publication)
EPUB ist ein offener Standard für eBooks und eignet sich besonders zur Darstellung von Belletristik und Sachbüchern. Der Fließtext wird dynamisch an die Display- und Schriftgröße angepasst. Auch für mobile Lesegeräte ist EPUB daher gut geeignet.
Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen eine
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen eine
Geräteliste und zusätzliche Hinweise
Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.
aus dem Bereich