Trace Elements in Health (eBook)

A Review of Current Issues

J. Rose (Herausgeber)

eBook Download: PDF

2016 | 1. Auflage
334 Seiten
Elsevier Science (Verlag)
9781483191959 (ISBN)

Infos

Trace Elements in Health: A Review of Current Issues presents how some metals affect health, growth, and well-being of man and animals in a variety of ways, when the amounts involved are excessive or deficient. This book discusses the various aspects of trace elements in three points of view. First, the toxicological and beneficial properties are described in eleven chapters. Chapter 1 deals with general toxicological properties, while Chapters 2 to 11 reviews advances in the field of elements that include cadmium, copper, indium, thallium, lead, mercury, molybdenum, selenium, zinc, and transuranic series. The next chapters focus on the genetic effects, health of children, and birth rate problems related to trace elements. Finally, this text concludes with a discussion on the role of trace elements in agriculture, focusing on requirements of plants and animals, consequences of excesses and imbalances of trace elements in soils, and animal diets. This publication is valuable to veterinarians and practitioners of disciplines such as physiology, dietetics, and medicine.

Inhalt

Front Cover 1
Trace Elements in Health: A Review of Current Issues 4
Copyright Page 5
Table of Contents 16
Dedication 3
Preface 6
List of contributors 8
Chapter summaries 10
Chapter 1. Toxicological properties of trace elements 
18 
Introduction 18
Biological response to metals 18
Local toxicity of metals 20
Systemic toxicity of metals 24
Biochemical mechanisms underlying metal toxicity 30
Conclusions 33
References 34
Chapter 2. Cadmium in animal and human health 38
Introduction 38
Cadmium in man 39
Effect of cadmium on animals 45
References 57
Chapter 3. Copper in human and animal health 
61 
Introduction 61
History 61
Copper in tissues and fluids 62
Metabolism of copper 68
Biological function of copper 71
Copper toxicity 76
Diseases of copper metabolism 78
Copper medicinals 80
Chapter 4. Indium and thallium in health 91
Introduction 91
Indium 91
Thallium 93
References 97
Chapter 5. Sources and effects of environmental lead 100
Introduction 100
Sources of environmental lead 101
Effects of lead on the central nervous system: neurobehavioural effects of lead 118
Lead toxicity and nutritional status 131
Conclusion 133
References 134
Chapter 6. Mercury in human and animal health 149
Introduction 149
Pathological effects on the nervous system 149
Pathological effects on the kidney 153
Pathological effects on the liver 154
Congenital methylmercury poisoning 156
References 163
Chapter 7. Molybdenum in animal and human health 167
Introduction 167
The distribution of molybdenum in animal tissues and fluids 167
Biochemistry of molybdenum 170
Pathologic states of molybdenum intake 176
Areas of interest for the future 179
References 180
Chapter 8. Selenium and health 184
Introduction 184
Selenium deficiency states in animals 184
Toxicity 190
Selenium and human related diseases 192
Recommended daily intake in man 194
References 195
Chapter 9. Zinc in animal and human health 199
Introduction 199
Zinc deficiency effects 200
Functions and mechanisms of action of zinc 201
Zinc toxicity 201
Zinc metabolism and homeostasis 202
Zinc requirements and effect of other factors on zinc metabolism 203
Zinc content and availability in foods and feeds 204
Other practical aspects 204
References 205
Chapter 10. Transuranic elements in animal and human health 210
Introduction 210
Sources of transuranic elements in the environment 211
Distribution and potential transport to animals and humans 214
Health effects on animals and humans 218
Conclusions 221
References 222
Chapter 11. Genetic aspects and trace element tolerance in man and animals 226
Introduction 226
Reproduction and growth 226
Sex-linked responses 228
Variable gene expression 229
Mutagenic, teratogenic and carcinogenic effects 229
Mutagenic studies (in vitro) 229
Mutagenic studies (in vivo) 232
Teratogenic effect 232
Carcinogenic effects 232
Inherited trace element diseases 233
Resistance to xenobiotics 234
Mechanism of trace element tolerance 236
Intracellular inclusion bodies 238
Metal—protein complexes 241
References 243
Chapter 12. Trace elements and the unborn: review and preliminary implications for policy 248
Introduction 248
History 250
Sources of trace elements during pregnancy 251
Toxicity considerations 252
Specific elements 253
Discussion 261
References 263
Chapter 13. Trace elements in pregnancy 267
Introduction 267
Trace elements and disease 268
Essential trace elements in pregnancy and development 272
Toxic trace elements 279
Conclusions 282
References 285
Chapter 14. Trace elements and the birth rate 288
Introduction 288
Materials and methods 289
Results 290
Discussion 300
References 301
Chapter 15. Trace elements in agriculture 303
Introduction 303
Trace element requirements of plants and animals 303
Function of trace elements in living organisms 306
Trace element problems in agriculture 309
Conclusion 317
References 318
Index 324

Produkt-Details

• Erscheint lt. Verlag: 29.7.2016
• Sprache: englisch
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Humanbiologie
• Themenwelt: Naturwissenschaften ► Chemie
• Themenwelt: Technik
• ISBN-13: 9781483191959 / 9781483191959