Preparation of Solutions Isoosmotic with Blood, Tears, and Tissue (eBook)

C. G. Lund, E. Peulicke Nielsen, K. Pedersen-Bjergaard (Autoren)

eBook Download: PDF

2013 | 1. Auflage
174 Seiten
Elsevier Science (Verlag)
978-1-4832-8122-3 (ISBN)

Infos

The Preparation of Solutions Isoosmotic with Blood, Tears, and Tissue provides the data needed to establish rules in the formulation of extemporaneous isoosmotic eye preparations for use in the new Danish Pharmacopoeia. The book provides a large number of freezing point and vapor pressure determinations of solutions of appropriate drugs. From the data obtained, proposals were made for the correction of prescriptions relating to eye preparations in the Dispensatorium Danicum. It was also shown how isoosmotic solutions can easily be obtained for extemporaneous preparations in general. By using curves in the present work it will be possible to prepare isotonic solutions of a large number of the commonly employed remedies in therapeutics, both for injection and for application to the eyes. They enable the pharmacist to prepare extemporaneously described fluids of the correct osmotic concentration. It is hoped that this text may also be of value to the work in other pharmaceutical laboratories in Denmark, and abroad.

Inhalt

Front Cover 1
The Preparation of Solutions Isoosmotic with Blood, Tears, and Tissue 4
Copyright Page 5
Table of Contents 10
Chapter 1. Introduction 16
Chapter 2. Osmotic pressure, vapour pressure, boiling point elevation, and freezing point depression 17
2. Available methods of determination 21
3. Experimental technique 22
4. Discussion of the errors 24
Chapter 3. The preparation of isoosmotic eye drops 38
1. Previous investigations of the composition of lachrymal fluid, and the requirements that ideal eye drops should fulfil 38
2. Own investigations 40
3. Substances examined 40
4. Double logarithmic system of coordinates 46
5. Results 52
6. Activity relations 74
7. Control of the eye drops described in Dispensatorium Danicum 75
8. Eye lotions 76
9. Summary 77
10. References 83
Chapter 4. The preparation of isoosmotic solutions for injection and for local treatment of tissues 85
1. Previous investigations of the osmotic pressure of blood 85
2. Substances examined 87
3. Results 94
4. Activity relations 157
5. Discussion 159
6. Control of the official solutions for injection 163
7. Control of the official solutions for local application to tissues 166
8. Summary 167
9. References 169
Chapter 5. Abbreviations 170
Chapter 6. Index Latin 171
Chapter 7. Index English 173

Produkt-Details

• Erscheint lt. Verlag: 22.10.2013
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• ISBN-10: 1-4832-8122-1 / 1483281221
• ISBN-13: 978-1-4832-8122-3 / 9781483281223