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Basic Neurochemistry

Molecular, Cellular and Medical Aspects
Buch | Hardcover
1104 Seiten
1993 | 5th Revised edition
Lippincott Williams and Wilkins (Verlag)
9780781701044 (ISBN)
CHF 98,35 inkl. MwSt
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The fifth edition of this reference textbook on basic neurochemistry. Most chapters have been revised to provide features such as all-new accounts of olfaction and taste, expanded coverage of histamine and serotonin, and approaches to inherited neurological degenerative disorders.
Virtually all the chapters have been rewritten for this edition, many by new, internationally recognized contributors. This text is a reference and textbook on basic neurochemistry. Highlights include: all-new accounts of olfaction and taste, glutamate and aspartate, GABA, glycine, purinergic transmitter systems, neuropeptides, G-proteins and cyclic nucleotides in the nervous system, molecular targets of abused drugs, neurotransmitter uptake systems, neurotoxicity, and fluid and solute regulation; revised and strategically expanded coverage of histamine and serotonin; significantly expanded coverage of neurotransmitters, receptor families, and second messenger systems; timely updates on molecular genetic approaches to inherited neurological degenerative disorders and mitochondrial diseases; extensive references to the current literature including citations of 1993 publications.

Part 1 Neural membranes: neurocellular anatomy; cell membrane structure and functions; membrane transport; electrical excitability and ion channels; lipids; myelin formation, structure and biochemistry; molecular biology of vision; olfaction and taste in vertebrates - molecular and organizational strategies underlying perception. Part 2 Synaptic function: chemically mediated synaptic transmission - an overview; receptors and signal transduction - classification and quantitation; acetylcholine; catecholamines; serotonin; histamine; opioid peptides and opioid receptors; neuropeptides; excitatory amino acid transmitters; GABA and glycine; purinergic systems; phosphoinositides; G-proteins and cyclic nucleotides in the nervous system; protein phosphorylation and the regulation of neuronal function; eicosanoids. Part 3 Molecular neurobiology: gene expression in the mammalian nervous system; molecular probes for gene expression; molecular genetic approaches to inherited neurological. Part 4 Cellular neurochemistry: degenerative disorders; axonal transport and the neuronal cytoskeleton; development of the nervous system; neural plasticity and regeneration; biochemistry of aging in the mammaliam brain; circulation and energy metabolism of the brain; blood-brain-cerebrospinal fluid barrier. Part 5 Medical neurochemistry: the muscle fibre and disorders of muscle excitability; diseases of carbohydrate, fatty acid, and mitochondrial metabolism; vitamin and nutritional deficiencies; biochemistry of neuropathy; diseases involving myelin; genetic disorders of lipid, glycoprotein, and mucopolysaccharide metabolism; disorders of amino acid metabolism; metabolic encephalopathies and coma; molecular targets of abused drugs; ischemia and hypoxia; epileptic seizures; neurotransmitters and disorders of the basal ganglia; biochemistry of Alzheimer's disease; positron emission tomography. Part 6 Behavioural neurochemistry: biochemical aspects of the psychotic disorders; biochemical hypotheses of mood and anxiety; endocrine effects on the brain and their relationships to behaviour; learning and memory.

Erscheint lt. Verlag 1.11.1993
Zusatzinfo 99 halftones, 238 illustrations, 77 tables, references
Verlagsort Philadelphia
Sprache englisch
Maße 178 x 254 mm
Gewicht 2100 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Naturwissenschaften Biologie Humanbiologie
Naturwissenschaften Biologie Zoologie
ISBN-13 9780781701044 / 9780781701044
Zustand Neuware
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