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Genetic Diversity in European Populations: Evolutionary Evidence and Medical Implications

Special Topic Issue: Human Heredity 2013, Vol. 76, No. 3-4

A. Sanchez-Mazas, G. Barbujani (Herausgeber)

Buch | Softcover

88 Seiten

2014
Karger, S (Verlag)
978-3-318-02679-5 (ISBN)

Lese- und Medienproben

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Although it is the continent with the lowest genomic diversity, Europe embraces a significant degree of variation, shaped by complex demographic events and locus-specific selective factors linked to environmental conditions. The European genetic diversity observed today has also important clinical and epidemiological implications. Different questions related to these topics are addressed in this special topic issue of eight excellent papers written by specialized European teams. The papers document the remarkable progress achieved in the last years in exploring human genomic diversity, both in past and present populations, in reconstructing complex scenarios of European peopling history using sophisticated data analyses and computer simulations, in identifying signatures of adaptive selection in milk digestion- and immune-related genes, and in applying this knowledge to crucial health issues, from tissue transplantation to disease associations. Genetic Diversity in European Populations: Evolutionary Evidence and Medical Implications is of special interest to researchers and students in biological and medical sciences and clinicians, who wish to update their knowledge in the field of European genetic diversity for basic research and medical applications.

Erscheint lt. Verlag	23.6.2014
Zusatzinfo	18 fig., 4 in color, 11 tab.
Verlagsort	Basel
Sprache	englisch
Maße	210 x 280 mm
Gewicht	322 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
Schlagworte	Anthropology • epidemiology • evolutionary biology • Genetics • Genetik • Genetik / Erblehre • Human genetics • immunology • Transplantation
ISBN-10	3-318-02679-4 / 3318026794
ISBN-13	978-3-318-02679-5 / 9783318026795
Zustand	Neuware