Transgenerational Epigenetics
Academic Press Inc (Verlag)
9780124059443 (ISBN)
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Epidemiological studies have suggested that environmental factors may be heritable. In fact, environmental factors often play a role in transgenerational epigenetics, which may have selective or adverse effects on the offspring. This epigenetic information can be transferred through a number of mechanisms including DNA methylation, histone modifications or RNA and the effects can persist for multiple generations.
This book examines the evolution of epigenetic inheritance, its expression in animal and plant models, and how human diseases, such as metabolic disorders and cardiovascular diseases, appear to be affected by transgenerational epigenetic inheritance. It discusses clinical interventions in transgenerational epigenetic inheritance that may be on the horizon to help prevent diseases before the offspring are born, or to reduce the severity of diseases at the very earliest stages of development in utero, and current controversies in this area of study, as well as future directions for research.
Dr. Tollefsbol is a Distinguished Professor at the University of Alabama at Birmingham. He holds doctorates in molecular biology and osteopathic medicine, trained with National Academy of Science members and has over 200 peer-reviewed publications. Reports highlighting the translatability to the lay public of the discoveries made in his laboratory have appeared in international media representing >50 million readers. Dr. Tollefsbol has been featured as an Investigator in the Spotlight by the NIH as well as a Scientist in the Spotlight by ScienceNow. He is an Associate Editor for Frontiers in Genetics, a contributor to Lewin’s GENES classic textbook and Lead Editor for Elsevier’s Translational Epigenetics Series. Dr. Tollefsbol has been named a “Highly Ranked Scholar worldwide (ScholarGPS). He has been invited for numerous endowed keynote presentations, his research has been highlighted in eScience News and ScienceDaily and he has published 20 scholarly books on topics related to his research.
1. Transgenerational Epigenetics
2. Historical Perspective of Transgenerational Epigenetics
3. Epidemiology of Transgenerational Epigenetics
4. Metastable Epiallels
5. Paramutations
6. Epigenetic Silencing of Transgenes
7. Epigenetic Inheritance of Repeat Sequences
8. Histone-mediated Transgenerational Epigenetics
9. Heritable Generational Effects Through RNA
10. Animal Models of Transgenerational Epigenetic Effects
11. Plant Models of Transgnerational Epigenetic Inheritance
12. Transgenerational Epigenetic Effects in Plants
13. Maternal Epigenetic Inheritance
14. Paternal Epigenetic Inheritance
15. Evolution of Transgenerational Epigenetic Inheritance
16. Heritable Epigenetics Over Multiple Generations
17. Maternal Stress Effects on Transgenerational Epigenetics
18. Preimplantation Environment and Epigenetic Transgenerational Inheritance
19. Transgenerational Epigenetic Inheritance and Human Disease
20. Environmental Transgenerational Epigenetic Effects
21. Transgenerational Epigenetics of Endocrine Disruptors
22. Effects of Transgenerational Epigenetics on Longevity
23. Transgenerational Epigenetic Effects of an Environmental Enrichment on Memory Formation
24. Dietary Effects on Transgenerational Epigenetic Inheritance
25. Clinical Applications of Transgenerational Epigenetics
26. Transgenerational Epigenetics: Current Controversies
27. Future Directions of Transgenerational Epigenetic Research
| Verlagsort | San Diego |
|---|---|
| Sprache | englisch |
| Maße | 216 x 276 mm |
| Gewicht | 1450 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete |
| Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| Naturwissenschaften ► Biologie ► Ökologie / Naturschutz | |
| ISBN-13 | 9780124059443 / 9780124059443 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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