Zum Hauptinhalt springen
Nicht aus der Schweiz? Besuchen Sie lehmanns.de

Textbook of Influenza (eBook)

eBook Download: EPUB
2014 | 2. Auflage
John Wiley & Sons (Verlag)
978-1-118-63683-1 (ISBN)

Lese- und Medienproben

Textbook of Influenza - Robert G. Webster, Arnold S. Monto, Thomas J. Braciale, Robert A. Lamb
Systemvoraussetzungen
173,99 inkl. MwSt
(CHF 169,95)
Der eBook-Verkauf erfolgt durch die Lehmanns Media GmbH (Berlin) zum Preis in Euro inkl. MwSt.
  • Download sofort lieferbar
  • Zahlungsarten anzeigen

The Textbook of Influenza is a comprehensive resource covering all aspects of influenza, from the genetic and molecular biology of the virus through to clinical aspects of the disease and the latest drug developments and treatments. This new edition has been completely revised and reflects the integration of disciplines concerning the emergence, evolution, pathogenesis and control of influenza viruses in the field of human and veterinary public health.

Textbook of Influenza examines the lessons learnt from the latest pandemic and provides the current state of knowledge for many yet unresolved issues related to virus origin, spread, pathogenesis and disease severity to better prepare for future pandemics. It covers the background to recent advances in influenza genomics and reverse genetics which have allowed the identification of virus virulence factors and the analysis and reconstruction of influenza viruses such as the 1918 Spanish flu strain.

This new edition is divided into eight key sections, containing chapters co-written by international experts from both the clinical and scientific communities, covering:
• Influenza Perspectives
• Structure and Replication
• Evolution and Ecology
• Epidemiology and Surveillance
• Immunology
• Vaccines and Vaccine Development
• Clinical Aspects and Antivirals
• Public Health

Textbook of Influenza is for all those working in the area of influenza including clinical and basic scientists, immunologists, molecular and structural virologists, public health officials and global pandemic control planners.



Edited by:
Robert G. Webster, Division of Virology, Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis
Arnold S. Monto, School of Public Health, University of Michigan, Ann Arbor, Michigan
Thomas J. Braciale, University of Virginia School of Medicine, Charlottesville, Virginia
Robert A. Lamb, Howard Hughes Medical Institute, Department of Molecular Biosciences, Northwestern University, Evanston, Illinois

Edited by: Robert G. Webster, Division of Virology, Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis Arnold S. Monto, School of Public Health, University of Michigan, Ann Arbor, Michigan Thomas J. Braciale, University of Virginia School of Medicine, Charlottesville, Virginia Robert A. Lamb, Howard Hughes Medical Institute, Department of Molecular Biosciences, Northwestern University, Evanston, Illinois

List of contributors, ix

Foreword to the second edition, xiv

Preface to the second edition, xvi

Acknowledgments, xvii

PART 1 Influenza: Perspective

1 Human influenza: One health, one world, 3
Daniel B. Jernigan and Nancy J. Cox

2 Influenza pandemics: History and lessons learned, 20
Arnold S. Monto and Robert G. Webster

PART 2 Structure and replication

3 Structure, disassembly, assembly, and budding of influenzaviruses, 37
Debiprosad Nayak, Sakar Shivakoti, Rilwan A. Balogun, GwendolynLee, and Z. Hong Zhou

4 The virus genome and its replication, 57
Robert M. Krug and Ervin Fodor

5 Influenza glycoproteins: Hemagglutinin and neuraminidase,67
Rupert J. Russell, Steven J. Gamblin, and John J. Skehel

6 Proton channels of influenza A and B viruses, 101
Chunlong Ma, Lawrence H. Pinto, and Robert A. Lamb

7 The NS1 protein: A master regulator of host and viralfunctions, 114
Robert M. Krug and Adolfo García-Sastre

8 Structure and function of the influenza virus replicationmachinery and PB1-F2, 133
Andrew Mehle and Jonathan A McCullers

9 The genome and its manipulation: Recovery of the 1918 virusand vaccine virus generation, 146
Gabriele Neumann and Yoshihiro Kawaoka

10 Pathogenesis, 157
Hans Dieter Klenk, Wolfgang Garten, and MikhailMatrosovich

PART 3 Evolution and ecology of influenza viruses

11 Ecology and evolution of influenza viruses in wild anddomestic birds, 175
Ron A.M. Fouchier and Yi Guan

12 Influenza in swine, 190
Richard Webby and Juergen Richt

13 Equine/Canine/Feline/Seal influenza, 203
Thomas M. Chambers, Edward J. Dubovi, and Ruben O. Donis

14 Emergence and Evolution of the 1918, 1957, 1968, and 2009pandemic virus strains, 218
Taia T. Wang and Peter Palese

PART 4 Epidemiology and surveillance

15 Influenza surveillance and laboratory diagnosis, 231
Maria Zambon

16 Epidemiology of influenza, 250
Marc-Alain Widdowson and Arnold S. Monto

PART 5 Immunology of influenza

17 Innate immunity, 269
Akiko Iwasaki and Malik Peiris

18 Antibody-mediated immunity, 283
Nicole Baumgarth,Michael C. Carroll, and SantiagoGonzalez

19 Cell-mediated immunity, 298
Stephen J. Turner, Peter C. Doherty, and Anne Kelso

PART 6 Vaccines and vaccine development

20 Immunogenicity, efficacy of inactivated/live virus seasonaland pandemic vaccines, 313
Wendy A. Keitel, Kathleen M. Neuzil, and John Treanor

21 New approaches to vaccination, 327
Chih-Jen Wei, Damian C. Ekiert, Gary J. Nabel, and Ian A.Wilson

22 Control of influenza in animals, 337
Ilaria Capua and Dennis J. Alexander

23 Influenza vaccine production, 352
Klaus Stöhr

PART 7 Clinical aspects and antivirals

24 Human influenza: Pathogenesis, clinical features, andmanagement, 373
Frederick G. Hayden and Menno D. de Jong

25 Antivirals: Targets and use, 392
Michael G. Ison and Alan Hay

26 The control of influenza and cost-effectiveness ofinterventions, 419
Carolyn B. Bridges, Samuel K. Peasah, and Martin I.Meltzer

27 Applications of quantitative modeling to influenza virustransmission dynamics, antigenic and genetic evolution, andmolecular structure, 434
Marc Lipsitch and Derek Smith

28 Pandemic preparedness and response, 453
Jonathan S. Nguyen-Van-Tam and Joseph Bresee

29 Influenza: The future, 470
Thomas J. Braciale

PART 8 The outbreak of H7N9

30 Appendix, 479
Thomas J. Bracial

List of Contributors

Dennis J. Alexander, OBE, PhD, FSB, FRCPath, DSc

Formerly Head, Virology Department

Animal Health and Veterinary Laboratories

Weybridge, Addlestone, Surrey, UK

 

Rilwan A. Balogun

Microbiology, Immunology and Molecular Genetics

David Geffen School of Medicine

University of California, Los Angeles; and

California NanoSystems Institute (CNSI)

Los Angeles, CA, USA

 

Nicole Baumgarth, DVM, PhD

Professor, Center for Comparative Medicine and

Department of Pathology, Microbiology and

Immunology, University of California

Davis, CA, USA

 

Thomas J. Braciale, MD, PhD

Director, Beirne B. Carter Center for Immunology

Research, Beirne B. Carter Professor in Immunology

Professor of Pathology and Microbiology, Immunology, and Cancer Biology

University of Virginia School of Medicine

Charlottesville, VA, USA

 

Joseph Bresee, MD

Chief, Epidemiology and Prevention Branch

Influenza Division

Centers for Disease Control and Prevention

Atlanta, GA, USA

 

Carolyn B. Bridges, MD, FACP

CAPT USPHS, Associate Director for Adult

Immunizations, Immunization Services Division

National Center for Immunizations and Respiratory Diseases

Centers for Disease Control and Prevention

Atlanta, GA, USA

 

Ilaria Capua, DVM, PhD

Director, OIE/FAO Reference Laboratory for Avian

Influenza and Newcastle Disease

OIE Collaborating Center for Diseases

at the Human-Animal Interface

Istituto Zooprofilattico Sperimentale delle Venezie

Padua, Italy

 

Michael C. Carroll, PhD

Professor, Department of Pediatrics

Harvard Medical School; and

Program in Cellular and Molecular Medicine

Children's Hospital, Boston, MA, USA

 

Thomas M. Chambers, PhD

Professor, Gluck Equine Research Center

Department of Veterinary Science

University of Kentucky

Lexington, KY, USA

 

Nancy J. Cox, PhD

Director, Influenza Division

National Center for Immunization and Respiratory Diseases

Centers for Disease Control and Prevention

Atlanta, GA, USA

 

Menno D. de Jong, MD, PhD

Professor in Clinical Virology

Head of Department of Medical Microbiology

Academic Medical Center

University of Amsterdam, Amsterdam

The Netherlands

 

Peter C. Doherty, PhD, FRS

Department of Microbiology and Immunology

The University of Melbourne, Melbourne, VIC, Australia; and

Department of Immunology

St Jude Children's Research Hospital

Memphis, TN, USA

 

Ruben O. Donis, DVM, PhD

Centers for Disease Control and Prevention

Atlanta, GA, USA

 

Edward J. Dubovi, PhD

Director, Virology Section

Animal Health Diagnostic Center

College of Veterinary Medicine

Cornell University

Ithaca, NY, USA

 

Damian C. Ekiert, PhD

Department of Integrative Structural and

Computational Biology

The Scripps Research Institute

La Jolla, CA, USA

 

Ervin Fodor, DPhil

Professor of Virology

Sir William Dunn School of Pathology

University of Oxford, Oxford, UK

 

Ron A. M. Fouchier, PhD

Professor in Molecular Virology

Department of Viroscience

Erasmus MC Rotterdam, The Netherlands

 

Steven J. Gamblin, PhD, FRS, FMedSci

MRC, National Institute for Medical Research

London, UK

 

Adolfo García-Sastre, PhD

Professor, Department of Microbiology

Fishberg Professor, Department of Medicine

Division of Infectious Diseases; and

Director Global Health and Emerging Pathogens Institute

Icahn School of Medicine at Mount Sinai

New York, NY, USA

 

Wolfgang Garten, PhD

Professor, Institut für Virologie

Philipps-Universität Marburg

Marburg, Germany

 

Santiago Gonzalez, PhD

Institute for Research in Biomedicine

Bellinzona, Switzerland

 

Yi Guan, PhD, MD

Director, State Key Laboratory of Emerging

Infectious Diseases

The University of Hong Kong; and

Professor, Centre of Influenza Research

and School of Public Health

Li Ka Shing Faculty of Medicine

The University of Hong Kong

Hong Kong SAR, China

 

Alan J. Hay, PhD

Virology Division, MRC National Institute

for Medical Research, London, UK

 

Frederick G. Hayden, MD

Professor of Medicine

Stuart S. Richardson Professor of Clinical Virology

University of Virginia School of Medicine

Charlottesville, VA, USA

 

Michael G. Ison, MD, MS, FIDSA

Associate Professor of Medicine and Surgery

Divisions of Infectious Diseases and Organ

Transplantation, Northwestern University

Feinberg School of Medicine

Chicago, IL, USA

 

Akiko Iwasaki, PhD

Professor, Department of Immunobiology

Howard Hughes Medical Institute

Yale University School of Medicine

New Haven, CT, USA

 

Daniel B. Jernigan, MD, MPH

Deputy Director, Influenza Division, National

Center for Immunization and Respiratory Diseases

Centers for Disease Control and Prevention

Atlanta, GA, USA

 

Yoshihiro Kawaoka, DVM, PhD

Professor of Virology, Influenza Research Institute

Department of Pathobiological Sciences

School of Veterinary Medicine

University of Wisconsin-Madison, Madison WI, USA; and

Department of Special Pathogens

International Research Center for Infectious Diseases

Institute of Medical Science

University of Tokyo; and

Division of Virology

Department of Microbiology and Immunology

Institute of Medical Science

University of Tokyo; and

ERATO Infection-Induced Host Responses Project

Saitama, Japan

 

Wendy A. Keitel, MD

Kyle and Josephine Morrow Chair in Molecular

Virology and Microbiology; and

Professor, Molecular Virology and Microbiology

and Medicine, Baylor College of Medicine

Houston, TX, USA

 

Anne Kelso, PhD

Director, WHO Collaborating Centre for

Reference and Research on Influenza

North Melbourne, VIC, Australia

 

Hans-Dieter Klenk, MD

Professor Emeritus, Institut für Virologie

Philipps-Universität Marburg

Marburg, Germany

 

Robert M. Krug, PhD

Professor and Chair

Department of Molecular Genetics and Microbiology

Fellow, Mr. and Mrs. Corbin J. Robertson

Sr. Regents Chair in Molecular Biology

Institute for Cellular and Molecular Biology

University of Texas at Austin

Austin, TX, USA

 

Robert A. Lamb, PhD, ScD

John Evans Professor of Molecular and Cellular

Biology, Howard Hughes Medical Institute

Department of Molecular Biosciences

Northwestern University

Evanston, IL, USA

 

Gwendolyn Lee

Microbiology, Immunology and Molecular Genetics

David Geffen School of Medicine

University of California, Los Angeles; and

California NanoSystems Institute (CNSI)

Los Angeles, CA, USA

 

Marc Lipsitch, DPhil

Professor of Epidemiology

Center for Communicable Disease Dynamics

Harvard School of Public Health

Boston, MA, USA

 

Chunlong Ma, PhD

Research Associate, Department of Neurobiology

Department of Molecular Biosciences

Northwestern University, Evanston, IL, USA

 

Mikhail Matrosovich, PhD

Group Leader, Institut für Virologie

Philipps-Universität Marburg

Marburg, Germany

 

Jonathan A. McCullers, MD

Dunavant Professor and Chair

Department of Pediatrics

University of Tennessee Health Sciences Center; and

Pediatrician-in-Chief

Le Bonheur Children's Hospital, Memphis; and

Member, Department of Infectious Diseases

St. Jude Children's Research Hospital

Memphis, TN, USA

 

Andrew Mehle, PhD

Assistant Professor

Department of Medical Microbiology and Immunology

University of Wisconsin Madison

Madison, WI, USA

 

Martin I. Meltzer, MS, PhD

Senior Health Economist and

Distinguished Consultant

Lead, Health...

Erscheint lt. Verlag 6.1.2014
Sprache englisch
Themenwelt Medizin / Pharmazie Allgemeines / Lexika
Medizinische Fachgebiete Innere Medizin Pneumologie
Studium Querschnittsbereiche Infektiologie / Immunologie
Schlagworte Aspects • Clinical • comprehensive resource • Control • disciplines • Disease • Edition • Emergence • Field • Genetic • Grippe • Health • infectious disease • Infektionskrankheiten • Influenza • Integration • Latest • latest drug • Medical Science • Medizin • molecular • New • Public • State • Textbook • Virus • Viruses
ISBN-10 1-118-63683-X / 111863683X
ISBN-13 978-1-118-63683-1 / 9781118636831
Informationen gemäß Produktsicherheitsverordnung (GPSR)
Haben Sie eine Frage zum Produkt?
EPUBEPUB (Adobe DRM)

Kopierschutz: Adobe-DRM
Adobe-DRM ist ein Kopierschutz, der das eBook vor Mißbrauch schützen soll. Dabei wird das eBook bereits beim Download auf Ihre persönliche Adobe-ID autorisiert. Lesen können Sie das eBook dann nur auf den Geräten, welche ebenfalls auf Ihre Adobe-ID registriert sind.
Details zum Adobe-DRM

Dateiformat: EPUB (Electronic Publication)
EPUB ist ein offener Standard für eBooks und eignet sich besonders zur Darstellung von Belle­tristik und Sach­büchern. Der Fließ­text wird dynamisch an die Display- und Schrift­größe ange­passt. Auch für mobile Lese­geräte ist EPUB daher gut geeignet.

Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen eine Adobe-ID und die Software Adobe Digital Editions (kostenlos). Von der Benutzung der OverDrive Media Console raten wir Ihnen ab. Erfahrungsgemäß treten hier gehäuft Probleme mit dem Adobe DRM auf.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen eine Adobe-ID sowie eine kostenlose App.
Geräteliste und zusätzliche Hinweise

Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.

Mehr entdecken
aus dem Bereich
interdisziplinäre Diagnostik und Therapie bei Erwachsenen und Kindern

von Boris A. Stuck; Anna Heidbreder; Joachim T. Maurer …

eBook Download (2025)
Springer Berlin Heidelberg (Verlag)
CHF 68,35
Vorbereitung anhand von Fällen, Fragen und Antworten

von Gerrit Montag

eBook Download (2024)
Springer Berlin Heidelberg (Verlag)
CHF 38,95