De novo Molecular Design

Gisbert Schneider (Herausgeber)

Software / Digital Media

576 Seiten

2013
Wiley-VCH Verlag GmbH (Hersteller)
978-3-527-67701-6 (ISBN)

Infos

Systematically examining current methods and strategies, this ready reference covers a wide range of molecular structures, from organic-chemical drugs to peptides, proteins and nucleic acids, in line with emerging new drug classes derived from biomacromolecules.A leader in the field and one of the pioneers of this young discipline has assembled here the most prominent experts from across the world to provide first-hand knowledge. While most of their methods and examples come from the area of pharmaceutical discovery and development, the approaches are equally applicable for molecular probes and diagnostics, pesticides, and any other molecule designed to interact with a biological system. Hundreds of images and screenshots, many of them in full color, illustrate the examples and method descriptions.With its broad and balanced coverage, this will be the first-stop resource for medicinal chemists, biochemists and biotechnologists for many years to come.

Autor

Gisbert Schneider is full professor of computer-assisted drug design at ETH Zurich, Switzerland. He studied biochemistry and computer science at the Free University of Berlin, Germany. After several international postdoctoral research activities he joined F. Hoffmann-La Roche Pharmaceuticals in Basel, Switzerland, where he headed the cheminformatics group. From 2002-2009 he was full professor of cheminformatics and bioinformatics (Beilstein Endowed Chair) at Goethe-University Frankfurt, Germany. Professor Schneider coined the terms "scaffold-hopping" and "frequent hitter" in drug design. His research activities concentrate on method development for adaptive molecular design and their tight integration with innovative chemical and biophysical techniques in drug discovery.

Produkt-Details

• Verlagsort: Weinheim
• Sprache: englisch
• Maße: 150 x 250 mm
• Gewicht: 666 g
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• ISBN-10: 3-527-67701-1 / 3527677011
• ISBN-13: 978-3-527-67701-6 / 9783527677016
• Zustand: Neuware