Schizophrenia (eBook)

Paul Harrison, Daniel R. Weinberger (Herausgeber)

eBook Download: EPUB

2011 | 3. Auflage
736 Seiten
Wiley (Verlag)
978-1-4443-4774-6 (ISBN)

Infos

Schizophrenia is one of the most complex and disabling diseases to affect mankind. Relatively little is known about its nature and its origins, and available treatments are inadequate for most patients. As a result, there are inevitable controversies about what causes it, how to diagnose it, and how best to treat it. However, in the past decade, there has been an explosion of new research, with dramatic discoveries involving genetic etiology and epidemiological risk factors. There has also been a catalog of new drugs coming to market, and controversy about the relative advantages and disadvantages of newer compared with older therapies. In addition, developing technologies in genomics, molecular biology and neuroimaging provide streams of new information. This book represents a definitive, essential, and up-to-date reference text on schizophrenia. It extensively and critically digests and clarifies recent advances and places them within a clinical context. The Editors (one American and one British), highly respected clinical psychiatrists and researchers and acknowledged experts on schizophrenia, have again assembled an outstanding group of contributors from the USA, UK, Europe and Australia, It will be of value to practising psychiatrists and to trainees, as well as to clinical and neuroscience researchers interested in keeping up with this field or coming into it. The book consists of four sections: descriptive aspects, biological aspects, physical treatments, and psychological and social aspects. It reviews the theoretical controversies over symptomatology, classification and aetiology (particularly pertinent as DSM-V is being developed), the relationship of schizophrenia to the other psychoses, the significance of positive and negative symptoms and pre-morbid personality. It describes a variety of approaches to integrating the vast research data about schizophrenia, including neurodevelopmental, genetic, pharmacological, brain imaging and psychological findings. The biological treatment section reviews the comparative efficacy of various drugs, the management of drug-resistant patients and both neurological and metabolic complications. The final section looks at psychological therapies, social outcomes, and the economics of schizophrenia. Highly Commended in the Psychiatry section of the 2012 BMA Book Awards.

Autor

Daniel R. Weinberger, Director: Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institute of Health, Bethesda, USA Paul J. Harrison, University Department of Psychiatry, Warneford Hospital, Oxford, UK

Inhalt

Contributors.

Editor's note.

Preface to the 3rd Edition.

Preface to the First Edition.

Part 1 Descriptive Aspects.

1. The concept of schizophrenia: past, present, and future(Nancy C. Andreasen).

2. The schizophrenia construct: symptomatic presentation(Celso Arango and William T. Carpenter).

3. Child and adolescent schizophrenia (Chris Hollis andJudith Rapoport).

4. Late onset schizophrenia (Robert Howard and Dilip V.Jeste).

5. The Schizophrenia Spectrum Personality Disorders (EranChemerinski and Larry J. Siever).

6. The prodome of schizophrenia (Shôn Lewis and JeanAddington).

7. Course and outcome (Wolfram an der Heiden and HeinzHäfner).

8. Neurocognitive Impairments in Schizophrenia: Their Characterand Their Role in Symptom Formation (Terry E. Goldberg, AnthonyDavid, James. M. Gold).

Part 2 BIOLOGICAL ASPECTS.

9. The secondary schizophrenias (Thomas M. Hyde and Maria A.Ron).

10. Schizophrenia: The epidemiological horizon (AssenJablensky, James B. Kirkbride and Peter B. Jones).

11. Environmental risk factors for schizophrenia (John J.McGrath and Robin M. Murray).

12. Classical Genetic Studies of Schizophrenia (Brien Rileyand Kenneth S. Kendler).

13. Genetic Associations in Schizophrenia (Michael CO'Donovan and Michael J. Owen).

14 . Intermediate phenotypes and genetic origins (TyroneCannon).

15. Electrophysiology of schizophrenia (Georg Winterer andRobert W. McCarley).

16. Structural Brain Imaging in schizophrenia and relatedpopulations (Stephen M. Lawrie and Christos Pantelis).

17. Functional Brain Imaging in schizophrenia (AndreasMeyer-Lindenberg).

18. Neuropathology of schizophrenia (Paul J. Harrison, DavidA. Lewis and Joel E. Kleinman).

19. Schizophrenia as a neurodevelopmental disorder (Daniel R.Weinberger).

20. Dopamine and Schizophrenia (Anissa Abi-Dargham andAnthony Grace).

21. Contributions of glutamate and GABA systems to theneurobiology and treatment of schizophrenia (John H. Krystal,M.D. and Bita Moghaddam).

22. Animal Models of schizophrenia (Barbara K. Lipska andJoseph A. Gogos).

Part 3 BIOLOGICAL TREATMENTS.

23. The pharmacology and neuroscience of antipsychotic drugs(John L. Waddington, Colm O'Tuathaigh and Gary J.Remington).

24. Principles of pharmacological treatment in schizophrenia(Thomas R. E. Barnes and Stephen R. Marder).

25. Comparative efficacy and effectiveness in the drug treatmentof schizophrenia (John Geddes, Mark Weiser, John M Davis andGrigori Joffe).

26. Approaches to treatment resistant patients (StefanLeucht, Cristoph U. Correll and John M. Kane).

27. Neurological complications of antipsychotic drugs (PeterM. Haddad and Venkata S. Mattay).

28. Metabolic and other side effects (John W. Newcomer andStefan Leucht).

Part 4 PSYCHOSOCIAL ASPECTS.

29. Schizophrenia and psychosocial stress (Paul E. Bebbingtonand Elizabeth Kuipers).

30. Mental health services for schizophrenia patients (TomBurns and Bob Drake).

31. Societal Outcomes in Schizophrenia (Ian Kooyman andElizabeth Walsh).

32. Psychological treatment of psychosis (Gillian Haddock andWiliam Spaulding).

33. Economics of the treatment of schizophrenia (Nancy H.Covell, Susan M. Essock, and Linda K. Frisman).

Index.

Colour plates are found facing page 338.

Rezensionen

"I thoroughly recommend this book as a well-integrated
collection of thoughtful and up-to-date expositions on every aspect
of schizophrenia, by some of the best scientists in the
field. " (Psychological Medicine, 2012)

"It will be of valuable to practising psychiatrists and to
trainees, as well as to the clinical and neuroscience researchers
interested in keeping up with this field or coming into
it." (Buchtipps, September 2012)

"The contributing authors and editors constitute an
international list of '"who's who" in contemporary schizophrenia
research. Overall this book represents a highly systematic,
comprehensive, scholarly, and critical appraisal of a core
component of modern psychiatry and a major publice health
challenge. It ably summarizes and evalutates efforts to better
understand the nature, diagnosis, biology, psychology, sociology
and clinical treatment of the group of largely "nonaffective"
psychotic disorders currently considered within the nosological
domain of schizophrenia. As such, it is an essential volume for
students, researchers, clinicians, and administrators interested in
improved understanding and care of persons diagnosed with psychotic
disorders." (Journal of Clinical Psychiatry, 2012)

Produkt-Details

• Erscheint lt. Verlag: 13.7.2011
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Psychiatrie / Psychotherapie
• Schlagworte: Abnormal Psychology • Krankenpflege • Krankenpflege i. d. Psychologie • Medical Science • Medizin • Mental Health Nursing • nursing • Psychiatrie • Psychiatry • Psychologie • Psychology • Psychopathologie • Schizophrenie
• ISBN-10: 1-4443-4774-8 / 1444347748
• ISBN-13: 978-1-4443-4774-6 / 9781444347746