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Evidence-Based Cardiology (eBook)

eBook Download: PDF
2008 | 2. Auflage
John Wiley & Sons (Verlag)
978-0-470-98687-5 (ISBN)

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This second editionis a ground-breaking clinical text with a strong emphasis on rigorous evidence. Leaders in the field discuss best practice in the light of systematic reviews and randomised control trials, and how best to treat where the information is less clear. Case histories provide intriguing discussions on how to apply the evidence in real life situations.

Evidence-based Cardiology also includes free access to the latest evidence, which is automatically posted on a companion website.



Salim Yusuf, OC FRSC is an Indian-born Canadian physician, the Marion W. Burke Chair in Cardiovascular Disease at McMaster University Medical School. He is a cardiologist and epidemiologist.

John A. Cairns, Dean, Faculty of Medicine, University of British Columbia.

A. John Camm, Professor of Clinical Cardiology and Head of the Department of Cardiac & Vascular Sciences at St George's, University of London.

Ernest L. Fallen, Professor Emeritus in Cardiology and Tutor in Cardiology Residency Program, McMaster University, Hamilton, Ontario.

Bernard J. Gersh, Professor of Medicine, Department of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota.


This second editionis a ground-breaking clinical text with a strong emphasis on rigorous evidence. Leaders in the field discuss best practice in the light of systematic reviews and randomised control trials, and how best to treat where the information is less clear. Case histories provide intriguing discussions on how to apply the evidence in real life situations. Evidence-based Cardiology also includes free access to the latest evidence, which is automatically posted on a companion website.

Salim Yusuf, OC FRSC is an Indian-born Canadian physician, the Marion W. Burke Chair in Cardiovascular Disease at McMaster University Medical School. He is a cardiologist and epidemiologist. John A. Cairns, Dean, Faculty of Medicine, University of British Columbia. A. John Camm, Professor of Clinical Cardiology and Head of the Department of Cardiac & Vascular Sciences at St George's, University of London. Ernest L. Fallen, Professor Emeritus in Cardiology and Tutor in Cardiology Residency Program, McMaster University, Hamilton, Ontario. Bernard J. Gersh, Professor of Medicine, Department of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota.

Evidence-based Cardiology 1
Contents 7
Contributors 13
Preface to the Second edition 19
Preface to the First edition 21
Glossary 23
Part I : General concepts and critical appraisal 27
1 What is evidence-based cardiology? 29
2 A critical appraisal of the cardiovascular history and physical examination 40
3 Obtaining incremental information from diagnostic tests 49
4 Clinical trials and meta-analysis 60
5 Finding current best evidence to practice evidence-based cardiology 66
6 Understanding concepts related to health economics 72
7 Introduction to decision analysis 82
8 Assessing and changing cardiovascular clinical practices 97
Part II : Prevention of cardiovascular diseases 115
9 Global perspective on cardiovascular disease 117
10 Tobacco: global burden and community solutions 129
11 Tobacco and cardiovascular disease: achieving smoking cessation 140
12 Lipids and cardiovascular disease 147
13 Use of lipid lowering agents in the prevention of cardiovascular disease 156
14 Blood pressure and cardiovascular disease 172
15 Glucose abnormalities and cardiovascular disease: “dysglycemia” as an emerging cardiovascular risk factor 187
16 Physical activity and exercise in cardiovascular disease prevention and rehabilitation 196
17 Psychosocial factors in the primary and secondary prevention of coronary heart disease: an updated systematic review of prospective cohort studies 207
18 Emerging approaches in cardiovascular prevention 245
19 Obesity 257
20 Postmenopausal hormone therapy and cardiovascular disease 270
21 Ethnicity and cardiovascular disease 285
22 The fetal origins of coronary heart disease 305
23 Molecular genetics of cardiovascular disorders 313
24 Cost effectiveness of prevention of cardiovascular disease 326
25 Diet and cardiovascular disease 335
Part IIIa : Specific cardiovascular disorders: Stable coronary artery disease 353
26 Anti-ischemic drugs 355
27 Impact of revascularization procedures in chronic coronary artery disease on clinical outcomes: a critical review of the evidence 365
28 Adjunctive medical therapy in percutaneous coronary intervention 386
29 Restenosis: etiologies and prevention 397
Part IIIb Specific cardiovascular disorders: Acute ischemic syndromes and acute myocardial infarction 421
30 Acute non-ST-segment elevation coronary syndromes: unstable angina and non-ST-segment elevation myocardial infarction 423
31 Fibrinolytic therapy 452
32 Mechanical reperfusion strategies in patients presenting with acute myocardial infarction 470
33 Adjunctive antithrombotic therapy for ST-elevation acute myocardial infarction 482
34 Pain relief, general management, and other adjunctive treatments 503
35 Complications after myocardial infarction 514
36 An integrated approach to the management of patients after the early phase of the acute coronary syndromes 533
Part IIIc : Specific cardiovascular disorders: Atrial fibrillation and supraventricular tachycardia 543
37 Atrial fibrillation: antiarrhythmic therapy 545
38 Atrial fibrillation: antithrombotic therapy 574
39 Atrial fibrillation: non-pharmacologic therapies 582
40 Supraventricular tachycardia: drugs v ablation 593
Part IIId : Specific cardiovascular disorders: Ventricular arrhythmias, bradyarrhythmias and cardiac arrest 601
41 Prevention and treatment of life-threatening ventricular arrhythmia and sudden death 603
42 Impact of pacemakers: when and what kind? 613
43 Syncope 645
44 Cardiopulmonary resuscitation 660
Part IIIe : Specific cardiovascular disorders: Left ventricular dysfunction 667
45 Prevention of congestive heart failure and treatment of asymptomatic left ventricular dysfunction 669
46 Management of overt heart failure 685
47 Acute myocarditis and dilated cardiomyopathy 707
48 Hypertrophic cardiomyopathy 729
49 Other cardiomyopathies 744
Part IIIf : Specific cardiovascular disorders: Pericardial disease 759
50 Pericardial disease: an evidence-based approach to diagnosis and treatment 761
Part IIIg : Specific cardiovascular disorders: Valvular heart disease 775
51 Rheumatic heart disease: prevention and acute treatment 777
52 Mitral valve disease: indications for surgery 784
53 Indications for surgery in aortic valve disease 793
54 Balloon valvuloplasty: aortic valve 808
55 Balloon valvuloplasty: mitral valve 822
56 Valve repair and choice of valves 835
57 Diagnosis and management of infective endocarditis 843
58 Antithrombotic therapy after heart valve replacement 858
Part IIIh : Specific cardiovascular disorders: Other conditions 863
59 Treatment of patients with stroke 865
60 Heart disease and pregnancy 879
61 Venous thromboembolic disease 890
62 Peripheral vascular disease 903
Part IV : Clinical applications 913
63 Clinical applications of external evidence 915
64 Stable angina: choice of PCI v CABG v drugs 918
65 Acute coronary syndromes 922
66 Acute myocardial infarction 928
67 Postmyocardial infarction: preventive measures 932
68 Metabolic risk and secondary prevention of coronary disease 935
69 Peripheral vascular disease with suspect coronary artery disease 938
70 Heart failure 941
71 Atrial fibrillation 947
72 Ventricular dysrhythmias: pharmacologic v non-pharmacologic treatment 951
73 Bradyarrhythmias: choice of pacemaker 957
74 Valvular heart disease: timing of surgery 960
Index 965

Erscheint lt. Verlag 15.4.2008
Reihe/Serie Evidence-Based Medicine
Evidence-Based Medicine
Evidence-Based Medicine
Sprache englisch
Themenwelt Medizin / Pharmazie Allgemeines / Lexika
Medizinische Fachgebiete Innere Medizin Kardiologie / Angiologie
Schlagworte Best • Cardiovascular Disease • CASE • clear • Clinical • Control • discuss • discussions • emphasis • Evidence • Field • groundbreaking • Histories • Information • Kardiovaskuläre Erkrankungen • Kardiovaskuläre Erkrankungen • Latest • LESS • Life • light • Medical Science • Medizin • Practice • provide • Real • Rigorous • situations • strong • Systematic
ISBN-10 0-470-98687-5 / 0470986875
ISBN-13 978-0-470-98687-5 / 9780470986875
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