Cancer Diagnostics with DNA Microarrays (eBook)

Steen Knudsen (Autor)

eBook Download: PDF

2006 | 1. Auflage
204 Seiten
John Wiley & Sons (Verlag)
978-0-470-04109-3 (ISBN)

Infos

Authored by an international authority in the field,Cancer
Diagnostics with DNA Microarrays is a complete reference
work on the rapidly growing use of DNA microarray data in the
diagnosis of and treatment planning for a large number of human
cancers.

* Uniquely deals with direct clinical application of microarray
data to oncology diagnosis, leading to more effective diagnosis of
and clearer treatment regimens for a wide range of
human cancers

* Offers clinicians summary presentation of state-of-the-art
science of DNA microarrays

* Each chapter includes bibliographic and further reading
suggestions

* Easily accessible, assuming no special training in statistics
or bioinformatics

Replete with examples and mini-cases, Cancer Diagnostics
with DNA Microarrays offers cancer researchers in private,
pharmacologic, and governmental institutions, biomedical
statisticians, and practicing oncologists concise,
thoughtfully authored guidance on the use of microarray data and
analysis as clinical tools. The text carefully addresses the needs
of end users - researchers and physicians -
using microarrays as a tool to be applied in common
clinical situations, and is of interest for students in medicine
and biology and professionals in health care as well.

Autor

STEEN KNUDSEN, PhD, is Director of Research at the Medical Prognosis Institute where he is now taking DNA microarrays into the clinic. Dr. Knudsen is a pioneer in the field of bioinformatics, having published a groundbreaking paper in Nature in 1990. He is also author of the critically acclaimed Guide to the Analysis of DNA Microarray Data (Wiley).

Inhalt

Preface.

Acnowldegments.

1. Introduction to DNA Microarray Technology.

2. Image Analysis.

3. Basic Data Analysis.

4. Visualization by Reduction of Dimensionality.

5. Cluster Analysis.

6. Molecular Classifiers for Cancer.

7. Survival Analysis.

8. Meta-Analysis.

9. The Design of Probes.

10. Software Issues and Data Formats.

11. Breast Cancer.

12. Leukemia.

13. Lymphoma.

14. Lung Cancer.

15. Bladder Cancer.

16. Colon Cancer.

17. Ovarian Cancer.

18. Prostate Cancer.

19. Melanoma.

20. Brain Tumors.

21. Organ or Tissue Specific Classification.

22. Sample Collection and Stability.

References.

Index.

Rezensionen

"...a ground-breaking addition...the best manual presently available on the use of DNA Microarrays in frontline cancer research." (Electric Review, February/March 2007)

Produkt-Details

• Erscheint lt. Verlag: 3.11.2006
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Anamnese / Körperliche Untersuchung
• Themenwelt: Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
• Themenwelt: Technik
• Schlagworte: Bioinformatics & Computational Biology • Bioinformatik • Bioinformatik u. Computersimulationen in der Biowissenschaften • Biotechnologie • Biotechnologie i. d. Biowissenschaften • Biotechnology • Biowissenschaften • Cell & Molecular Biology • Diagnostik • Krebs (Medizin) • Life Sciences • Zell- u. Molekularbiologie
• ISBN-10: 0-470-04109-9 / 0470041099
• ISBN-13: 978-0-470-04109-3 / 9780470041093