Injectable Drug Development

Techniques to Reduce Pain and Irritation

Pramod K. Gupta, Gayle A. Brazeau (Herausgeber)

Buch | Hardcover

472 Seiten

1999
Crc Press Inc (Verlag)
978-1-57491-095-7 (ISBN)

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Filled with strategies to minimize the adverse effects of injectable drugs, this book provides the scientific background and techniques required to evaluate parenteral formulations with respect to their potential to cause pain, irritation, and muscle damage. Using a unique, interdisciplinary approach, the book's editors and contributors represent the areas of pharmaceutics, physiology, anatomy, toxicology, and product formulation. The chapters cover topics such as muscle damage with injectables, in vitro and in vivo cystolic enzyme release, histological and morphological methods, assessing pain, cosolvents in injectables, biodegradable microparticles, and more.

Pramod K. Gupta, Gayle A. Brazeau

Challenges. Pain, Irritation & Damage. Muscle Damage with Injectables. In Vitro Evaluation of Intravascular Hemolysis. Lesion & Edema Models. Rat Paw-Lick Model. Radiopharmaceuticals for Noninvasive Evaluation. In Vitro & In Vivo Cytosolic Enzyme Release. Histological & Morphological Methods. Assessing Pain. Cosolvents in Injectables. Prodrugs. Complexation-Cyclodextrins. Liposomal Formulations. Biodegradable Microparticles. Emulsions. Minimizing Injection Pain & Damage.

Erscheint lt. Verlag	31.5.1999
Verlagsort	Bosa Roca
Sprache	englisch
Maße	178 x 254 mm
Gewicht	1030 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
ISBN-10	1-57491-095-7 / 1574910957
ISBN-13	978-1-57491-095-7 / 9781574910957
Zustand	Neuware