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Rapid Clinical Pharmacology (eBook)

A Student Formulary
eBook Download: EPUB
2011
John Wiley & Sons (Verlag)
978-1-118-29306-5 (ISBN)

Lese- und Medienproben

Rapid Clinical Pharmacology - Andrew Batchelder, Charlene Rodrigues, Ziad Alrifai
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This pocket reference guide is a must for all medical students and junior doctors preparing for exams in pharmacology or needing a rapid reminder during a clinical attachment.

In light of the growing pressures on those who prescribe drugs to patients, increasing emphasis has been placed on the importance of pharmacology in the undergraduate medical curriculum. Rapid Clinical Pharmacology, with its concise, easy-to-use approach, offers an appealing format for students to use in both clinical practice and exam preparation and its 'one-page per drug/class' layout easily facilitates the generation of a personal student formulary.

Each chapter of the book mirrors each section of the BNF to allow easy cross-referencing and then each chapter is divided into consistent sections as per other books in the Rapid series.

Rapid Clinical Pharmacology will also be available as a mobile application for iPhone, iPod Touch, iPad and Blackberry. See wiley.com/go/mededapps for further details.



Andrew Batchelder is Core Trainee in Surgery University Hospitals of Leicester NHS Trust

Charlene Rodrigues is Academic Clinical Fellow in Paediatric Infectious Diseases, Imperial College, London

Ziad Alrifai is Core Trainee in Anaesthetics, University Hospitals of Nottingham NHS Trust

Adrian Stanley is Consultant Physician in Cardiovascular Medicine and Honorary Senior Lecturer (Medical Education) at University Hospitals of Leicester NHS Trust


This pocket reference guide is a must for all medical students and junior doctors preparing for exams in pharmacology or needing a rapid reminder during a clinical attachment. In light of the growing pressures on those who prescribe drugs to patients, increasing emphasis has been placed on the importance of pharmacology in the undergraduate medical curriculum. Rapid Clinical Pharmacology, with its concise, easy-to-use approach, offers an appealing format for students to use in both clinical practice and exam preparation and its one-page per drug/class' layout easily facilitates the generation of a personal student formulary. Each chapter of the book mirrors each section of the BNF to allow easy cross-referencing and then each chapter is divided into consistent sections as per other books in the Rapid series. Rapid Clinical Pharmacology will also be available as a mobile application for iPhone, iPod Touch, iPad and Blackberry. See wiley.com/go/mededapps for further details.

Andrew Batchelder is an Academic doctor at University Hospitals of Leicester (UHL). Charlene Rodrigues is an Academic doctor at the London Deanery. Ziad Alrifai is an Academic doctor at University Hospitals of Leicester (UHL). Adrian Stanley is a Consultant Physician in Cardiovascular Medicine and Honorary Senior Lecturer (Medical Education), UHL.

Preface, ix

List of abbreviations, xi

Basic pharmacokinetic concepts

Gastrointestinal system

Histamine type 2 receptor antagonists, 5

Laxatives, 6

Proton pump inhibitors (PPIs), 7

Cardiovascular system

a-adrenoceptor antagonists (a blockers), 8

Adenosine, 9

Aldosterone antagonists, 10

Amiodarone, 11

Angiotensin-converting enzyme inhibitors (ACEIs), 12

Angiotensin II receptor blockers (ARBs), 13

Antimuscarinics, 14

Aspirin, 15

b-adrenoceptor antagonists (b blockers), 16

Calcium channel blockers (CCBs), 18

Cardiac glycosides, 19

Clopidogrel, 20

Dipyridamole, 21

Fibrates, 22

Fibrinolytics, 23

Flecainide, 24

Glycoprotein IIb/IIIa inhibitors, 25

Inotropic sympathomimetics, 26

Loop diuretics, 27

Low molecular weight heparins (LMWH), 28

Nitrates, 29

Potassium channel activators, 30

Statins, 31

Thiazide diuretics, 32

Tranexamic acid, 33

Vasoconstrictor sympathomimetics, 34

Warfarin, 35

Respiratory system

b2 adrenoceptor agonists, 36

Histamine type 1 receptor antagonists, 37

Inhaled antimuscarinics, 38

Leukotriene receptor antagonists, 39

Oxygen, 40

Theophylline, 41

Central nervous system

5-HT1 agonists (triptans), 42

5-HT3 antagonists, 43

Antihistamine anti-emetics, 44

Antipsychotics - atypical, 45

Antipsychotics - typical, 46

Benzodiazepines, 47

Carbamazepine, 48

Dopamine antagonist anti-emetics, 49

Drugs for dementia, 50

Gabapentin and pregabalin, 51

Levodopa (L-dopa), 52

Lithium, 53

Monoamine oxidase inhibitors (MAOIs), 54

Non-steroidal anti-inflammatory drugs (NSAIDs), 55

Opioid analgesia, 56

Other antiepileptics, 57

Other antiparkinsonian drugs, 58

Paracetamol, 59

Phenothiazine anti-emetics, 60

Phenytoin, 61

Selective serotonin reuptake inhibitors (SSRIs), 62

Sodium valproate, 63

Tricyclic antidepressants (TCAs), 64

Infections

Aciclovir, 65

Aminoglycosides, 66

Antifungals, 67

Antiretroviral agents, 68

Antituberculosis drugs, 69

Cephalosporins and other b lactams, 70

Penicillins, 71

Glycopeptide antibiotics, 72

Macrolides, 73

Metronidazole, 74

Nitrofurantoin, 75

Quinolones, 76

Tetracyclines, 77

Trimethoprim, 78

Endocrine system

5a-reductase inhibitors, 79

Antidiuretic hormone (ADH) analogues, 80

Biguanides, 81

Bisphosphonates, 82

Carbimazole, 83

Corticosteroids, 84

Dipeptidylpeptidase-4 (DDP-4) inhibitors, 85

Gonadotrophin-releasing hormone (GnRH) agonists, 86

Hormone replacement therapy (HRT), 87

Incretin mimetics, 88

Insulins, 89

Levothyroxine, 90

Propylthiouracil, 91

Sulfonylureas, 92

Thiazolidinediones, 93

Obstetrics, gynaecology and urinary tract disorders

Contraceptives, 94

Mifepristone, 96

Oxybutynin, 97

Oxytocin, 98

Phosphodiesterase type 5 inhibitors, 99

Malignant disease and immunosuppression

Alkylating agents, 100

Anthracyclines, 101

Anti-androgens, 102

Antimetabolites, 103

Antiproliferative immunosuppressants, 104

Calcineurin inhibitors, 105

Other antineoplastic drugs, 106

Selective oestrogen receptor modulators (SERMs), 107

Trastuzumab (Herceptin), 108

Vinca alkaloids, 109

Musculoskeletal and joint diseases

Allopurinol, 110

Aminosalicylic acid compounds (ASAs), 111

Colchicine, 112

Methotrexate, 113

Contents vii

Eye

Antiglaucoma drugs, 114

Anaesthesia

Depolarising neuromuscular blocking agents, 115

Etomidate, 116

Inhalational anaesthetics, 117

Lidocaine, 118

Non-depolarising blocking agents, 119

Propofol, 120

Thiopental sodium, 121

Intravenous fluids

Blood and transfusion medicine

Index of drugs, 127

"This is an excellent pocket manual on core drugs for medical
practitioners, especially those practicing in a British-oriented
healthcare system." (Doody's, 13 January 2012)



"The book is practical and made more so by its availability for
mobile electronic devices such as iPhones, iPad, and so on. This
book represents an important step in application of medical
knowledge and technology by the bed side." (Journal of Tropical
Pediatrics, 1 November 2011)

List of abbreviations

5-HT 5-hydroxytryptamine (serotonin)
ACEIs Angiotensin-converting enzyme inhibitors
ACh Acetylcholine
ACS Acute coronary syndrome
ADH Antidiuretic hormone
ADP Adenosine diphosphate
AF Atrial fibrillation
AIDS Acquired immunodeficiency syndrome
APTT Activated partial thromboplastin time
ARBs Angiotensin receptor blockers
ASA Aminosalicylic acid
ATP Adenosine triphosphate
AV Atrioventricular
AVNRT AV nodal re-entry tachycardia
BM Boehringer Mannheim (finger-prick blood glucose)
BP Blood pressure
BTS British Thoracic Society
Ca2+ Calcium ion
cAMP Cyclic adenosine monophosphate
CCBs Calcium channel blockers
CCF Congestive cardiac failure
CD4+ Cluster of differentiation 4
cGMP Cyclic guanosine monophosphate
Cl- Chloride ion
CMV Cytomegalovirus
CNS Central nervous system
CO2 Carbon dioxide
COCP Combined oral contraceptive pill
COMT Catechol-O-methyl transferase
COPD Chronic obstructive pulmonary disease
COX Cyclo-oxygenase
CSF Cerebrospinal fluid
CT Computed tomography
CTG Cardiotocography
CTZ Chemoreceptor trigger zone
CVP Central venous pressure
DIC Disseminated intravascular coagulation
DKA Diabetic ketoacidosis
DNA Deoxyribonucleic acid
DVT Deep vein thrombosis
EBV Epstein Barr virus
ECG Electrocardiography
ESR Erythrocyte sedimentation rate
FBC Full blood count
FFP Fresh frozen plasma
FSH Follicule-stimulating hormone
G6PD Glucose-6-phosphate dehydrogenase deficiency
GABA Gamma aminobutyric acid
GFR Glomerular filtration rate
GI Gastrointestinal
GLUT Glucose transporters
GnRH Gonadotrophin-releasing hormone
GPIIb/IIIa Glycoprotein IIb/IIIa
GTN Glyceryl trinitrat
GTP Guanosine triphosphate
GU Genito-urinary
H+ Hydrogen ion
H1 Histamine type 1 receptor
H2 Histamine type 2 receptor
HDL High density lipoproteins
HER2 Human epidermal growth factor receptor 2
HIV Human immunodeficiency virus
HMG CoA 3-hydroxy-3-methylglutaryl coenzyme A
HONK Hyperosmolar non-ketotic state
HRT Hormone replacement therapy
IHD Ischaemic heart disease
IN Intranasal
INR International normalised ratio
ISMN Isosorbide mononitrate
JVP Jugular venous pressure
K+ Potassium ion
L-dopa Levodopa
LDL Low-density lipoproteins
LFTs Liver function tests
LH Luteinising hormone
LMWH Low molecular weight heparin
LRTI Lower respiratory tract infection
LV Left ventricular
LVF Left ventricular failure
M2 Muscarinic type 2 receptors
M3 Muscarinic type 3 receptors
MAO Monoamine oxidase
MAOIs Monoamine oxidase inhibitors
MI Myocardial infarction
MMSE Mini-mental state examination
mRNA Messenger ribonucleic acid
N2O Nitrous oxide
Na+ Sodium ion
NICE National Institute for Health and Clinical Excellence
NMDA N-methyl-D-aspartic acid
NNRTIs Non-nucleoside reverse transcriptase inhibitors
NRTIs Nucleoside reverse transcriptase inhibitors
NSAID Non-steroidal anti-inflammatory drugs
O2 Oxygen
OCP Oral contraceptive pill
PCA Patient-controlled analgesia
PCOS Polycystic ovarian syndrome
PE Pulmonary embolism
PGs Prostaglandins
PIs Protease inhibitors
PO By mouth (per os)
POP Progesterone-only pill
PONV Post-operative nausea and vomiting
PPAR Peroxisome proliferator-activated receptors
PPI Proton pump inhibitor
PR Per rectum
PSA Prostate-specific antigen
QTc Corrected QT interval
RNA Ribonucleic acid
SA Sino-atrial
SERM Selective oestrogen receptor modulator
SLE Systemic lupus erythematosus
SNRIs Serotonin and noradrenaline reuptake inhibitors
SSRIs Selective serotonin reuptake inhibitors
SVT Supraventricular tachycardia
Half-life
T3 Tri-iodothyronine
T4 Tetra-iodothyronine
TCAs Tricyclic antidepressants
TFTs Thyroid function tests
TIA Transient ischaemic attack
TPR Total peripheral resistance
tRNA Transfer ribonucleic acid
TSH Thyroid-stimulating hormone
U&Es Urea and electrolytes
UTI Urinary tract infection
VF Ventricular fibrillation
VLDL Very low-density lipoproteins
VT Ventricular tachycardia
VTE Venous thromboembolism

Abbreviations of routes of...

Erscheint lt. Verlag 28.11.2011
Reihe/Serie Rapid
Rapid
Rapid
Mitarbeit Koordination: Adrian Stanley
Sprache englisch
Themenwelt Medizin / Pharmazie Gesundheitsfachberufe
Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Schlagworte Clinical • concise • doctors • Drug • Drugs • emphasis • Exams • Format • growing • Guide • importance • Junior • Layout • light • Medical • medical curriculum • Medical Science • Medizin • patients • pharmacology • Pharmacology & Pharmaceutical Medicine • Pharmakologie • Pharmakologie u. Pharmazeutische Medizin • pocket • pressures • Reference • Student • students • undergraduate
ISBN-10 1-118-29306-1 / 1118293061
ISBN-13 978-1-118-29306-5 / 9781118293065
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