Apolipoproteins
Regulatory Functions, Health Effects & Role in Disease
Seiten
2013
Nova Science Publishers Inc (Verlag)
978-1-62257-484-1 (ISBN)
Nova Science Publishers Inc (Verlag)
978-1-62257-484-1 (ISBN)
Apolipoproteins are proteins that bind lipids (oil-soluble substances such as fat and cholesterol) to form lipoproteins. They transport the lipids through the lymphatic and circulatory systems. Apolipoproteins also serve as enzyme cofactors, receptor ligands, and lipid transfer carriers that regulate the metabolism of lipoproteins and their uptake in tissues. In this book, the authors present current research in the study of the regulatory functions, health effects and role in disease of apolipoproteins. Topics include macrophages, apolipoproteins, steroid hormones and molecular mechanisms of cell proliferation; formation of discoidal apolipoprotein A-1 lipid bound complexes; the role of apolipoprotein E in cardiovascular and renal disease; the functional variants and mutations of the apolipoprotein A5 gene in human pathology; and regulation of FGF-1 of ApoE/HDL generation in astrocytes.
Preface; Macrophages, Lipo(Apo)Proteins, Steroid Hormones, & Molecular Mechanisms of Cell Proliferation; Current Concepts on the Formation of Discoidal Apolipoprotein A-I Lipid Bound Complexes: From Picket Fences to a Double-Belt Model via Inter-Ring Rotation of Apolipoprotein A-I Monomers; Understanding the Role of Apolipoprotein E in Cardiovascular & Renal Diseases; Role of Functional Variants & Mutations of the Apolipoprotein A5 Gene in Human Pathology; Mechanism of Antiinflammatory Action of the High Density Lipoproteins & Apolipoprotein A-I; Apolipoprotein A-I Motifs in Discoidal High Density Lipoproteins Influence Lecithin: Cholesterol Acyltransferase Activity; Regulation by FGF-1 of ApoE/HDL Generation in Astrocytes; Index.
| Verlagsort | New York |
|---|---|
| Sprache | englisch |
| Maße | 155 x 230 mm |
| Gewicht | 496 g |
| Themenwelt | Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie |
| ISBN-10 | 1-62257-484-2 / 1622574842 |
| ISBN-13 | 978-1-62257-484-1 / 9781622574841 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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