Engineering Biosensors (eBook)

Kinetics and Design Applications

Ajit Sadana (Autor)

eBook Download: PDF

2001 | 1. Auflage
404 Seiten
Elsevier Science (Verlag)
978-0-08-052363-7 (ISBN)

Infos

Biosensors are becoming increasingly important bioanalytical tools in the pharmaceutical, biotechnology, food, and other consumer oriented industries. The technology, though well developed in Europe, is slowly developing and has begun to generate interest in the United States only over the past couple of years. Research is now being directed toward the development of biosensors that are versatile, economical, and simple to use.

Engineering Biosensors is a comprehensive introduction to biosensors that includes numerous illustrations to further explain the main concepts and practical examples from existing literature. It describes what biosensors are, where they are used, and how their performance is affected by existing surface characteristics.

A better understanding of biosensors, as provided by this book, will greatly assist in the design of new as well as the improvement of existing biosensors. Readers are also provided with invaluable and hard-to-find data on the economics of the biosensor market to assist them in better understanding the market and where it is heading.

Inhalt

Cover 1
Contents 8
Preface 12
Chapter 1. Introduction 16
1.1 Background, Definition, and the Need for Biosensors 16
1.2 Assay Formats 25
1.3 Difficulties with Biosensor Applications 27
1.4 Newer Applications for Biosensors 28
1.5 Commercially Avialable Biosoensors 32
1.6 Biomedical Applications 32
1.7 Overview 34
Chapter 2. Influence of Diffusional Limitations and Reaction Order on Antigen–Antibody Binding Kinetics 38
2.1 Introduction 38
2.2 Theory 39
Chapter 3. Influence of Diffusional Limitations and Lateral Interactions on Antigen–Antibody Binding Kinetics 60
3.1 Introduction 60
3.2 Theory 61
3.3 Conclusions 78
Chapter 4. Fractal Reaction Kinetics 82
4.1 Introduction 82
4.2 Fractal Kinetics 84
Chapter 5. Influence of Different Parameters on Fractal Dimension Values During the Binding Phase 98
5.1 Introduction 98
5.2 Theory 100
5.3 Results 104
5.4 Summary and Conclusions 137
Chapter 6. Fractal Dimension and the Binding Rate Coefficient 142
6.1 Introduction 142
6.2 Theory 145
6.3 Results 148
6.4 Conclusions 198
Chapter 7. Fractal Dimension and the Dissociation Rate Coefficient 202
7.1 Introduction 202
7.2 Theory 205
7.3 Results 210
7.4 Conclusions 231
Chapter 8. Influence of Nonspecific Binding on the Rate and Amount of Specific Binding: A classical analysis 236
8.1 Introduction 236
8.2 Theory 245
Chapter 9. Influence of Nonspecific Binding on the Rate and Amount of Specific Binding: A Fractal Analysis 268
9.1 Introduction 268
9.2 Theory 270
9.3 Results 272
9.4 Other Examples of Interest 280
9.5 Conclusions 284
Chapter 10. Fractal Dimension and Hybridization 288
10.1 Introduction 288
10.2 Theory 290
10.3 Results 291
10.4 Conclusions 322
Chapter 11. Fractal Dimension and Analyte-Receptor Binding in Cells 326
11.1 Introduction 326
11.2 Theory 328
11.3 Results 330
11.4 Conclusions 356
Chapter 12. Surface Plasmon Resonance Biosensors 360
12.1 Introduction 360
12.2 Theory 362
12.3 Results 364
12.4 Conclusions 394
Chapter 13. Economics and Market for Biosensors 400
13.1 Introduction 400
13.2 Market Size and Economics 401
13.3 Development Cost of a Biosensor 408
13.4 Cost Reduction Methods 410
Index 414

Produkt-Details

• Erscheint lt. Verlag: 4.10.2001
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Pflege
• Themenwelt: Medizin / Pharmazie ► Physiotherapie / Ergotherapie ► Orthopädie
• Themenwelt: Naturwissenschaften ► Chemie
• Themenwelt: Technik ► Maschinenbau
• Themenwelt: Technik ► Medizintechnik
• Themenwelt: Technik ► Umwelttechnik / Biotechnologie
• ISBN-10: 0-08-052363-3 / 0080523633
• ISBN-13: 978-0-08-052363-7 / 9780080523637