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Handbook of Biosensors and Biosensor Kinetics -  Ajit Sadana,  Neeti Sadana

Handbook of Biosensors and Biosensor Kinetics (eBook)

eBook Download: EPUB
2010 | 1. Auflage
536 Seiten
Elsevier Science (Verlag)
978-0-08-093285-9 (ISBN)
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Biosensors are essential to an ever-expanding range of applications, including healthcare; drug design; detection of biological, chemical, and toxic agents; environmental monitoring; biotechnology; aviation; physics; oceanography; and the protection of civilian and engineering infrastructures. This book, like the previous five books on biosensors by this author (and one by the co-author), addresses the neglected areas of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces.

Topics are covered in a comprehensive fashion, with homogeneous presentation for the benefit of the reader. The contributors address the economic aspects of biosensors and incorporate coverage of biosensor fabrication and nanobiosensors, among other topics. The comments, comparison, and discussion presented provides a better perspective of where the field of biosensors is heading.


  • Serves as a comprehensive resource on biosensor analysis
  • Examines timely topics such as biosensor fabrication and nanobiosensors
  • Covers economic aspects and medical applications (e.g., the role of analytes in controlling diabetes)

Biosensors are essential to an ever-expanding range of applications, including healthcare; drug design; detection of biological, chemical, and toxic agents; environmental monitoring; biotechnology; aviation; physics; oceanography; and the protection of civilian and engineering infrastructures. This book, like the previous five books on biosensors by this author (and one by the co-author), addresses the neglected areas of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces. Topics are covered in a comprehensive fashion, with homogeneous presentation for the benefit of the reader. The contributors address the economic aspects of biosensors and incorporate coverage of biosensor fabrication and nanobiosensors, among other topics. The comments, comparison, and discussion presented provides a better perspective of where the field of biosensors is heading. - Serves as a comprehensive resource on biosensor analysis- Examines timely topics such as biosensor fabrication and nanobiosensors- Covers economic aspects and medical applications (e.g., the role of analytes in controlling diabetes)

Front cover 1
Handbook of Biosensors and Biosensor Kinetics 4
Copyright page 5
Contents 6
Preface 12
Chapter 1: Introduction 13
1.1. Introduction 13
1.2. Biosensor Markets and Economics 21
1.3. Chapter Contents 23
Chapter 2: Modeling and Theory 27
2.1. Introduction 27
2.2. Theory 31
Chapter 3: Fabrication of Biosensors 47
3.1. Introduction 48
3.2. Different Methods of Biosensor Fabrication 49
3.3. Conclusions 67
Chapter 4: Biosensors Involved in Drug Discovery 73
4.1. Introduction 73
4.2. Theory 74
4.3. Results 76
4.4. Conclusions 104
Chapter 5: Nanobiosensors 107
5.1. Introduction 107
5.2. Optical Dna Detection By Multifunctional Cross-Linked Au Nanoaggregates (Li Et al., 2009) 109
5.3. High-Performance Multiplexed Determination of Proteins: Determinations of Cancer Biomarkers in Serum and Saliva Using Qd 111
5.4. Carbon Nanofiber Paste Electrode Nonenzymatic Glucose Sensor (Liu Et al., 2009) 113
5.5. Use of Gold Nanoparticles in a Sensitive Immunochromatographic Assay for the Detection of Psa in Serum (Nagatani Et al., 116
5.6. In Vitro Characterization of an Intracellular Nanosensor For Ros (Henderson Et al., 2009) 117
5.7. Combined Fluorescence and Sers Molecular Beacon Assay To Detect Human Viral Rna (Sha Et al., 2007) 119
5.8. Nanotube-Based Biosensor for the Detection of Disease-Specific Autoantibodies in Human Serum (Drouvalakis Et al., 2008). 121
5.9. Gold Nanoparticle Amperometric Immunosensor (Biosensor) For Opg (Singh Et al., 2008) 123
5.10. Label-Free Antigen-Antibody Binding on a Gold Nanoparticle Sensor Array (Olkhov and Shaw, 2008) 125
5.11. Electrochemical Immunosensing Using Magnetic Beads and Gold Nanocatalysts (Selvaraju Et al., 2007) 128
5.12. Conclusions 130
Chapter 6: Binding of the Same Analyte to Different Biosensor Surfaces 141
6.1. Introduction 141
6.2. Theory 143
6.3. Results 144
6.5. Conclusions 171
Chapter 7: Binding of the Same Analyte (Glucose) to Different Biosensor Surfaces 181
7.1. Introduction 181
7.2. Theory 182
7.3. Results 184
7.4. Conclusions 205
Chapter 8: Medical Applications of Biosensors 209
8.1. Introduction 209
8.2. Theory 210
8.3. Results 212
8.4. Conclusions 232
Chapter 9: Physiological Cellular Reactions Detection on Biosensor Surfaces 235
9.1. Introduction 235
9.2 Theory 236
9.3. Results 238
9.4. Conclusions 264
Chapter 10: Detection of Gases on Biosensor Surfaces 267
10.1. Introduction 267
10.2. Theory 268
10.3. Results 270
10.4. Conclusions 304
Chapter 11: Detection of Analytes on Arrays/Microarrays/Dna Chips 309
11.1. Introduction 309
11.2. Theory 310
11.3. Results 311
11.4. Conclusions 344
Chapter 12: Binding and Dissociation Kinetics of Different Analytes on Novel Biosensing Surfaces 347
12.1. Introduction 347
12.2 Theory 348
12.3 Results 350
12.4 Conclusions 373
Chapter 13: Binding of Different Analytes on Biosensor Surfaces 377
13.1. Introduction 377
13.2. Theory 378
13.3. Results 380
13.4. Conclusions 396
Chapter 14: Toxins and Pollutants Detection on Biosensor Surfaces 401
14.1. Introduction 401
14.2. Theory 405
14.3. Results 406
14.4. Conclusions 430
Chapter 15: Fractal Analysis of the Binding and Dissociation Kinetics of Protein Biomarkers and Other Medically Oriented Anal 435
15.1. Introduction 435
15.2. Theory 436
15.3. Results 438
15.4 Conclusions 455
Chapter 16: Binding and Dissociation Kinetics During Hybridization on Biosensor Surfaces 461
16.1. Introduction 461
16.2. Theory 462
16.3. Results 464
16.4. Conclusions 494
Chapter 17: Economics of Biosensors 499
17.1. Introduction 499
17.2. Market Reports and Trends 500
17.3. Examples of Investment/Financing in Biosensor Companies 512
Index 519

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