Accelerating the Development of Biomarkers for Drug Safety

Workshop Summary

Development Forum on Drug Discovery and Translation, Board on Health Sciences Policy, Institute of Medicine (Autoren)

Robert Giffin, Sally Robinson (Herausgeber)

Buch | Softcover

100 Seiten

2009
National Academies Press (Verlag)
978-0-309-13124-7 (ISBN)

Artikel merken

Biomarkers can be defined as indicators of any biologic state, and they are central to the future of medicine. As the cost of developing drugs has risen in recent years, reducing the number of new drugs approved for use, biomarker development may be a way to cut costs, enhance safety, and provide a more focused and rational pathway to drug development. On October 24, 2008, the IOM's Forum on Drug Discovery, Development, and Translation held "Assessing and Accelerating Development of Biomarkers for Drug Safety," a one-day workshop, summarized in this volume, on the value of biomarkers in helping to determine drug safety during development.

1 Front Matter; 2 1 Introduction; 3 2 Overview of Key Issues; 4 3 Cardiac Safety Biomarkers; 5 4 Assessing and Predicting Kidney Safety; 6 5 Biomarkers of Acute Idiosyncratic Hepatocellular Injury in Clinical Trials; 7 6 Future Considerations; 8 Appendix A: Workshop Agenda; 9 Appendix B: Speaker Biographies

Erscheint lt. Verlag	20.8.2009
Verlagsort	Washington
Sprache	englisch
Maße	152 x 229 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
ISBN-10	0-309-13124-3 / 0309131243
ISBN-13	978-0-309-13124-7 / 9780309131247
Zustand	Neuware