Oxidative DNA Damage

Formation, Measurement and Biochemical Features

Jean Cadet, J. Richard Wagner (Autoren)

Buch | Hardcover

350 Seiten

2013
Imperial College Press (Verlag)
9781848163157 (ISBN)

Infos

Oxidative DNA damage is implicated in several major human diseases including cancer and neurological disorders, together with some forms of diabetes as well as aging. The direction of research in this area needs to keep pace with advances in technology. This textbook contains an account of this field at the interface of chemistry and biology.

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Oxidative DNA damage is implicated in several major human diseases including cancer and neurological disorders, together with some forms of diabetes as well as aging. The direction of research in this area needs to keep pace with advances in technology. However, until now there has been no single book that covers and reviews all of the major chemical and biochemical aspects associated with oxidative DNA damage. This timely textbook therefore contains an up-to-date account of this rapidly developing area at the interface of chemistry and biology.

Inhalt

Reactive Species Toward DNA Components; Characterization of Stable Products; Intermediates and Mechanistic Studies; Measurement of Oxidative DNA Damage; DNA Repair and Mutagenesis of Synthetic Oligonucleotides; Oxidative DNA Damage as Biomarker in Biology and Medicine.

Produkt-Details

• Erscheint lt. Verlag: 31.12.2013
• Verlagsort: London
• Sprache: englisch
• Themenwelt: Informatik ► Weitere Themen ► Bioinformatik
• Themenwelt: Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
• ISBN-13: 9781848163157 / 9781848163157
• Zustand: Neuware