Quantitative Systems Pharmacology
Springer International Publishing (Verlag)
978-3-032-02691-0 (ISBN)
Quantitative Systems Pharmacology as a discipline has matured over the past decade and is being used more frequently in academia and industry; however, dedicated training programs and courses are limited. This book will provide a go-to educational reference for a broad audience with topics including: the technology's history, comparisons to other modeling methods and emerging opportunities to bring methods together, best practice for implementation illustrated by real-world examples, and finally a summary of where the technology is headed in the future.
Part 1 Fundamental Modeling.- What Is QSP and Why Does It Exist A Brief History.- Breadth of Pharmacology Modeling Fundamentals of Pharmacokinetics, Pharmacodynamics, and Mechanistic Modeling.- A Framework for Quantitative Systems Pharmacology Model Execution.- Role of data in development and application of Quantitative Systems Pharmacology models.- Integrating QSP and ML to Facilitate Drug Development and Personalized Medicine.- Part 2 Model Development and Application.- Quantitative Systems Pharmacology Development and Application in Neuroscience.- Quantitative Systems Pharmacology Modeling in Immuno Oncology Hypothesis Testing, Dose Optimization, and Efficacy Prediction.- Application of Mechanistic Mathematical Modeling to Toxicology Quantitative Systems Toxicology (QST).- The Role of Cross Institutional and Interdisciplinary Collaboration in Defining and Executing a Quantitative Systems Pharmacology Strategy.- Part 3 Current Challenges and Future Direction.- Future Directions for Quantitative Systems Pharmacology.
| Erscheinungsdatum | 28.09.2025 |
|---|---|
| Reihe/Serie | Handbook of Experimental Pharmacology |
| Zusatzinfo | VIII, 354 p. 1 illus. |
| Verlagsort | Cham |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Themenwelt | Informatik ► Weitere Themen ► Bioinformatik |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie | |
| Medizin / Pharmazie ► Pharmazie | |
| Schlagworte | Mathematical Models • mechanistic • Pharmaceutics • Pharmacodynamics • pharmacology • Quantitative Systems Pharmacology |
| ISBN-10 | 3-032-02691-1 / 3032026911 |
| ISBN-13 | 978-3-032-02691-0 / 9783032026910 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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