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Precision Medicine, AI and the Science of Personalized Healthcare - James Wallace

Precision Medicine, AI and the Science of Personalized Healthcare

(Autor)

Buch | Hardcover
352 Seiten
2025
John Wiley & Sons Inc (Verlag)
978-1-394-34158-0 (ISBN)
CHF 54,10 inkl. MwSt
A fascinating combination of patient stories and scientific explanation shedding light on the most promising trend in healthcare today: precision medicine

In Precision Medicine, AI and the Science of Personalized Healthcare, senior researcher at Harvard Business School and former CEO of DecisionRx, a pioneering medication therapy optimization company, James Wallace, delivers an eye-opening new discussion of how cutting-edge precision medicine is transforming the cost, access, and outcomes of modern healthcare. The author relies on real-world experiences that showcase the practical, human benefits of precision medicine and how those benefits can accrue to people from all walks of life.

You'll discover how personalized treatments—those based on a patient's genetic, environmental, and lifestyle attributes—can do more than traditional medicine to combat a wide variety of genetic disorders, chronic illnesses, and treatment inefficiencies. You'll also learn about precision medicine's potential to lower healthcare costs for everyone while improving outcomes.

Inside the book:



Explorations of how precision medicine can address the triple crisis of cost, access, and quality that currently plagues the US healthcare system
Unique combinations of compelling human stories and accessible scientific explanations that render a complex subject approachable and relatable
A compelling argument for how the precision medicine movement can transform the healthcare system and the lives of the people who navigate it every day


Perfect for healthcare, technology, and business professionals grappling with the skyrocketing costs of patient care, Precision Medicine, AI and the Science of Personalized Healthcare is also a must-read for healthcare consumers frustrated by the current, “one-size-fits-all” approach to medicine.

JAMES WALLACE is the former CEO of DecisionRx, a medication therapy optimization company. He is a Senior Researcher at Harvard Business School. Wallace was previously the Head of Strategy for Anthem, the President of AmeriPlus, a combat pilot with the United States Army, and a strategy consultant with Bain & Company.

Foreword xvii

Preface xix

Introduction: The Dawn of a New Era xxi

Chapter 1 Michael and Jennifer: A Family’s Fight Against Obesity 1

Michael: The Silent Fighter 3

Jennifer: The Hopeful Realist 6

The Wearable Catalyst 10

A Hopeful Future 19

Chapter 2 Wearable Devices 21

Chronic Conditions: A Growing Concern 22

Wearables and Precision Medicine: Tailoring Health Solutions 28

Costs and Outcomes of Wearable Devices: Traditional vs. Precision Medicine 42

Notes 53

Chapter 3 The Science of Hope 59

Simplifying Precision Medicine 60

How It Works: From Data to Decisions 60

The Patient Perspective: Benefits Made Simple 62

Understanding the Impact of Wearables, Pharmacogenomics, Big Data Analytics, and Artificial Intelligence 65

Macro-Level Cost and Outcomes 70

The Universal Benefits of Precision Medicine 75

Notes 80

Chapter 4 Emily’s Unrest 85

A Life of Contrasts 85

Breaking Point 93

Pharmacogenomics: A Tailored Solution 100

A Renewed Emily 103

Chapter 5 Genetics and Medication Management 107

Medication Failure in Traditional Care 108

Precision Medicine’s Approach: Eliminating Trial and Error 113

The Role of Pharmacogenomics in Precision Medicine 122

Comparison of Cost and Outcomes: Traditional vs. Precision Medicine 129

Notes 134

Chapter 6 Through the Lens Clearly 141

Assembling the Pieces: The History of Medical Innovation 142

Implementing the Insights: From Bloodletting to Precision Medicine 152

Integrating the Outcomes: The Rise of Individualized Care 158

Notes 164

Chapter 7 The Joy and Pain of Being Amy 167

The Value of Work 168

A Lifetime of Shrugged Shoulders 172

A Voice of Concern 175

Treating the Person, Not the Symptoms 176

The Power of Knowing Why 177

It Takes a Village 180

Chapter 8 Pain and Personalized Therapy 185

The Hidden Epidemic of Pain 186

Data as Cure 191

Precision Pain Management in Action 198

Cost and Outcomes of Precision Pain Management 200

Notes 205

Chapter 9 Barriers to Access 209

The Challenges of Precision Medicine 210

Social Determinants of Health and Access to Care 217

Notes 221

Chapter 10 Susan, Family, and Cancer 223

Peggy Sue Got Married 223

The Family Years 225

Tuesday Afternoon 226

A Different Kind of Doctor 228

The Machine That Thinks 229

Moving the Mountain 232

A Life Reclaimed 234

Chapter 11 Artificial Intelligence and the Human Genome 237

The Intersection of Information and Artificial Intelligence 238

Genetic and Genomic Medicine 242

Cost and Outcomes: Advanced Personalized Treatments 252

Companies Shaping the Future of AI-Enabled Medicine 259

Notes 263

Chapter 12 A Vision for the Future 271

What’s Next for Precision Medicine 272

Implications for Traditional Medicine 277

How Precision Medicine Will Shape Personalized Healthcare 283

Notes 287

Conclusion: Making Medicine Personal 291

The Personal Healthcare Journey 291

Common Themes from our Guides: What We Can Learn 294

How You Can Explore Precision Medicine for Yourself 296

Call to Action: A Roadmap for Leaders, Investors, and Policymakers 299

Notes 302

Acknowledgments 303

About the Author 305

Index 307

Erscheinungsdatum
Verlagsort New York
Sprache englisch
Maße 160 x 231 mm
Gewicht 544 g
Themenwelt Informatik Weitere Themen Bioinformatik
Medizin / Pharmazie Medizinische Fachgebiete
Medizin / Pharmazie Physiotherapie / Ergotherapie Orthopädie
Technik Medizintechnik
Technik Umwelttechnik / Biotechnologie
ISBN-10 1-394-34158-X / 139434158X
ISBN-13 978-1-394-34158-0 / 9781394341580
Zustand Neuware
Informationen gemäß Produktsicherheitsverordnung (GPSR)
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