Mathematical Properties of Population-Genetic Statistics (eBook)

Quadratic Forms Most Beautiful

Noah A. Rosenberg (Autor)

eBook Download: PDF

2025
Princeton University Press (Verlag)
978-0-691-26157-7 (ISBN)

Infos

A powerful new approach to interpreting population-genetic data in evolution and ecologyPopulation genetics uses statistical analysis to catalog genetic variation among populations and species. Summary statistics computed from allele frequenciesmathematical functions that measure features of genetic similarity and diversityare key to this global effort. Yet despite their widespread use in evolutionary biology, ecology, and conservation biology, their mathematical properties have largely been overlooked. This book shows how to use the mathematical bounds on summary statistics to make better interpretations of population-genetic data.Noah Rosenberg discusses how the behavior of these statistics depends not only on the biology of the populations they seek to describe but also on the mathematical properties of the functions used to compute them, properties that produce constraints on the values of the statistics and influence their interpretation. Focusing on the concept of homozygositya quadratic function of allele frequencies in a populationhe demonstrates how to account for mathematical constraints when measuring genetic similarity and diversity. Rosenberg illustrates the results using examples from empirical data and shares strategies that readers can use to apply this mathematical perspective to different kinds of summary statistics, including those for measuring biodiversity in ecological communities.Drawing inspiration from Charles Darwin, who marveled at evolution's ';endless forms most beautiful and most wonderful,' this book presents a groundbreaking approach to the study of genetic variation. It is sure to stimulate new research in population biology and deeper thinking about the meaning and interpretation of essential measurements of the world's genomes.

Produkt-Details

• Erscheint lt. Verlag: 20.5.2025
• Reihe/Serie: Princeton Series in Theoretical and Computational Biology
• Zusatzinfo: 63 b/w illus.
• Sprache: englisch
• Themenwelt: Mathematik / Informatik ► Mathematik ► Statistik
• Themenwelt: Naturwissenschaften ► Biologie ► Evolution
• Themenwelt: Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
• Schlagworte: Applied mathematics • Computational Biology • conservation genetics • diversity indices • Diversity statistics • Evolution • Evolutionary genetics • Genetic data analysis • genetic diversity • Human genetics • Inequalities • Mathematical Biology • Mathematical Genetics • Mathematical Properties of Population-Genetic Statistics • molecular ecology • Natural selection • Noah Rosenberg • Population biology • Population Genetics • species diversity • Statistical genetics • summary statistics • Theoretical Biology
• ISBN-10: 0-691-26157-1 / 0691261571
• ISBN-13: 978-0-691-26157-7 / 9780691261577