Recent Trends in Gene Expression

Buch | Hardcover

403 Seiten

2013
Nova Science Publishers Inc (Verlag)
9781626186804 (ISBN)

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The term "Gene" refers to a segment of DNA present inside the genome that code for a protein. Depending on the organism, a particular genome may encode thousands of diverse types of genes responsible for various functions. These genes are differentially expressed and tightly regulated as needed at different stages of cell and physiological functions including cell differentiation and development. Gene expression may be influenced by various environmental and stimuli such as temperature, nutrients, hormones, stress etc. Though the fundamental mechanism of transcription (production of mRNA from the protein coding genes) is very similar in different organisms, the mechanism of gene regulation and the machineries involved are distinct for different organisms. In the post genomic and epigenomic era, it is increasingly being recognised that gene expression is not only controlled gene sequences but also various other non-genomic factors that include protein and DNA modifications and non-coding RNAs. Various aspects of gene expression in prokaryotes and eukaryotes, the mechanism of transcription and gene regulation and influences of various environmental factors are highlighted in different chapters of this book.

Preface; Mechanism of Transcription in Prokaryotes; How Noisy is RNA Production in Escherichia Coli When Seen in Vivo, One Event at a Time; The Biochemistry of F420 Cofactor Biosynthesis; Regulation of Gene Expression through Mrna Stability: Implications in Cancer Development & Therapeutics; Roles of Small RNAs in Regulation of Signaling & Adaptive Responses in Plants; Nuclear Organization of Cancer Cells; Insect Lipid Metabolism: Insights into Gene Expression Regulation; Blood Based Gene Expression: Useful Biomarkers for Alzheimers & Parkinsons Diseases; Microarray-Based Whole Transcriptome Expression Profiling as a Tool to Understand Human Ageing; Lessons from the Gene Expression Studies of Immunocompetent Cells in Relationship to Type 1 Diabetes Development; Current Technologies for Assessing Epigenetic Marks & their Utilization in the Study of Metal Carcinogenesis; Chromium (III): Bio-Significant or Bio-Toxic?; RMP: From Transcription to Oncogenesis; Index.

Erscheint lt. Verlag	1.7.2013
Verlagsort	New York
Sprache	englisch
Maße	180 x 260 mm
Gewicht	830 g
Themenwelt	Informatik ► Weitere Themen ► Bioinformatik
Themenwelt	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
ISBN-13	9781626186804 / 9781626186804
Zustand	Neuware